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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CEP78
Full Name:
Centrosomal protein of 78 kDa
Alias:
Type:
Mass (Da):
76396
Number AA:
689
UniProt ID:
Q5JTW2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
S
V
K
L
R
R
D
S
A
A
D
F
F
S
H
Site 2
Y21
D
F
F
S
H
Y
E
Y
L
C
A
L
Q
N
S
Site 3
S72
N
K
D
L
P
L
V
S
I
K
S
F
F
Q
P
Site 4
T84
F
Q
P
W
L
G
D
T
G
S
D
M
N
K
F
Site 5
Y101
S
R
V
P
A
I
R
Y
K
D
V
T
F
Q
L
Site 6
S174
I
I
C
Q
G
I
K
S
S
I
T
L
K
T
V
Site 7
S175
I
C
Q
G
I
K
S
S
I
T
L
K
T
V
N
Site 8
T180
K
S
S
I
T
L
K
T
V
N
F
T
G
C
N
Site 9
Y202
H
M
A
K
I
L
K
Y
Q
T
M
R
R
H
E
Site 10
T204
A
K
I
L
K
Y
Q
T
M
R
R
H
E
E
T
Site 11
T211
T
M
R
R
H
E
E
T
W
A
E
S
L
R
Y
Site 12
S215
H
E
E
T
W
A
E
S
L
R
Y
R
R
P
D
Site 13
Y218
T
W
A
E
S
L
R
Y
R
R
P
D
L
D
C
Site 14
S315
K
V
L
Q
N
G
R
S
A
K
S
E
Y
Q
W
Site 15
S318
Q
N
G
R
S
A
K
S
E
Y
Q
W
I
T
S
Site 16
Y320
G
R
S
A
K
S
E
Y
Q
W
I
T
S
P
S
Site 17
S325
S
E
Y
Q
W
I
T
S
P
S
V
K
E
P
S
Site 18
S327
Y
Q
W
I
T
S
P
S
V
K
E
P
S
K
T
Site 19
S332
S
P
S
V
K
E
P
S
K
T
A
K
Q
K
R
Site 20
T334
S
V
K
E
P
S
K
T
A
K
Q
K
R
R
T
Site 21
T341
T
A
K
Q
K
R
R
T
I
I
L
G
S
G
H
Site 22
T353
S
G
H
K
G
K
A
T
I
R
I
G
L
A
T
Site 23
T360
T
I
R
I
G
L
A
T
K
K
P
V
S
S
G
Site 24
S365
L
A
T
K
K
P
V
S
S
G
R
K
H
S
L
Site 25
S366
A
T
K
K
P
V
S
S
G
R
K
H
S
L
G
Site 26
S371
V
S
S
G
R
K
H
S
L
G
K
E
Y
Y
A
Site 27
Y376
K
H
S
L
G
K
E
Y
Y
A
P
A
P
L
P
Site 28
Y377
H
S
L
G
K
E
Y
Y
A
P
A
P
L
P
P
Site 29
T424
Q
Q
P
G
F
P
V
T
V
T
V
E
S
P
S
Site 30
T426
P
G
F
P
V
T
V
T
V
E
S
P
S
S
S
Site 31
S429
P
V
T
V
T
V
E
S
P
S
S
S
E
V
E
Site 32
S432
V
T
V
E
S
P
S
S
S
E
V
E
E
V
D
Site 33
S433
T
V
E
S
P
S
S
S
E
V
E
E
V
D
D
Site 34
S441
E
V
E
E
V
D
D
S
S
E
S
V
H
E
V
Site 35
S442
V
E
E
V
D
D
S
S
E
S
V
H
E
V
P
Site 36
S444
E
V
D
D
S
S
E
S
V
H
E
V
P
E
K
Site 37
S485
L
K
V
D
K
R
V
S
E
L
E
H
E
N
A
Site 38
S500
Q
L
R
N
I
N
F
S
L
S
E
A
L
H
A
Site 39
S502
R
N
I
N
F
S
L
S
E
A
L
H
A
Q
S
Site 40
S509
S
E
A
L
H
A
Q
S
L
T
N
M
I
L
D
Site 41
S523
D
D
E
G
V
L
G
S
I
E
N
S
F
Q
K
Site 42
S555
T
M
A
G
I
D
Q
S
D
F
Q
L
L
G
H
Site 43
S567
L
G
H
P
Q
M
T
S
T
V
S
N
P
P
K
Site 44
T568
G
H
P
Q
M
T
S
T
V
S
N
P
P
K
E
Site 45
S621
D
S
F
P
V
P
V
S
T
P
E
G
L
G
T
Site 46
T622
S
F
P
V
P
V
S
T
P
E
G
L
G
T
S
Site 47
T628
S
T
P
E
G
L
G
T
S
S
N
N
L
G
V
Site 48
T638
N
N
L
G
V
P
A
T
E
Q
R
Q
E
S
F
Site 49
S644
A
T
E
Q
R
Q
E
S
F
E
G
F
I
A
R
Site 50
S654
G
F
I
A
R
M
C
S
P
S
P
D
A
T
S
Site 51
S656
I
A
R
M
C
S
P
S
P
D
A
T
S
G
T
Site 52
T660
C
S
P
S
P
D
A
T
S
G
T
G
S
Q
R
Site 53
S661
S
P
S
P
D
A
T
S
G
T
G
S
Q
R
K
Site 54
S665
D
A
T
S
G
T
G
S
Q
R
K
E
E
E
L
Site 55
S673
Q
R
K
E
E
E
L
S
R
N
S
R
S
S
S
Site 56
S676
E
E
E
L
S
R
N
S
R
S
S
S
E
K
K
Site 57
S678
E
L
S
R
N
S
R
S
S
S
E
K
K
T
K
Site 58
S679
L
S
R
N
S
R
S
S
S
E
K
K
T
K
T
Site 59
S680
S
R
N
S
R
S
S
S
E
K
K
T
K
T
E
Site 60
T684
R
S
S
S
E
K
K
T
K
T
E
S
H
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation