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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AARS2
Full Name:
Alanyl-tRNA synthetase, mitochondrial
Alias:
Alanine--tRNA ligase
Type:
Mass (Da):
107322
Number AA:
985
UniProt ID:
Q5JTZ9
International Prot ID:
IPI00394788
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005739
GO:0005759
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0003824
GO:0004812
PhosphoSite+
KinaseNET
Biological Process:
GO:0006082
GO:0006139
GO:0006399
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
L
R
R
A
I
R
R
S
P
A
W
R
G
L
S
Site 2
S26
S
P
A
W
R
G
L
S
H
R
P
L
S
S
E
Site 3
S31
G
L
S
H
R
P
L
S
S
E
P
P
A
A
K
Site 4
S32
L
S
H
R
P
L
S
S
E
P
P
A
A
K
A
Site 5
S61
H
G
H
R
L
V
P
S
A
S
V
R
P
R
G
Site 6
S63
H
R
L
V
P
S
A
S
V
R
P
R
G
D
P
Site 7
S71
V
R
P
R
G
D
P
S
L
L
F
V
N
A
G
Site 8
T89
F
K
P
I
F
L
G
T
V
D
P
R
S
E
M
Site 9
S94
L
G
T
V
D
P
R
S
E
M
A
G
F
R
R
Site 10
S105
G
F
R
R
V
A
N
S
Q
K
C
V
R
A
G
Site 11
S126
E
D
V
G
R
D
L
S
H
H
T
F
F
E
M
Site 12
T129
G
R
D
L
S
H
H
T
F
F
E
M
L
G
N
Site 13
Y143
N
W
A
F
G
G
E
Y
F
K
E
E
A
C
N
Site 14
Y160
W
E
L
L
T
Q
V
Y
G
I
P
E
E
R
L
Site 15
Y171
E
E
R
L
W
I
S
Y
F
D
G
D
P
K
A
Site 16
T186
G
L
D
P
D
L
E
T
R
D
I
W
L
S
L
Site 17
S192
E
T
R
D
I
W
L
S
L
G
V
P
A
S
R
Site 18
S202
V
P
A
S
R
V
L
S
F
G
P
Q
E
N
F
Site 19
S255
H
N
R
E
A
D
G
S
L
Q
P
L
P
Q
R
Site 20
S282
A
V
L
Q
G
K
H
S
T
Y
D
T
D
L
F
Site 21
Y284
L
Q
G
K
H
S
T
Y
D
T
D
L
F
S
P
Site 22
T286
G
K
H
S
T
Y
D
T
D
L
F
S
P
L
L
Site 23
Y305
Q
G
C
R
A
P
P
Y
L
G
R
V
G
V
A
Site 24
T319
A
D
E
G
R
T
D
T
A
Y
R
V
V
A
D
Site 25
Y321
E
G
R
T
D
T
A
Y
R
V
V
A
D
H
I
Site 26
S344
D
G
I
F
P
G
M
S
G
P
P
L
V
L
R
Site 27
S361
L
R
R
A
V
R
F
S
M
E
I
L
K
A
P
Site 28
S374
A
P
P
G
F
L
G
S
L
V
P
V
V
V
E
Site 29
T382
L
V
P
V
V
V
E
T
L
G
D
A
Y
P
E
Site 30
Y387
V
E
T
L
G
D
A
Y
P
E
L
Q
R
N
S
Site 31
S394
Y
P
E
L
Q
R
N
S
A
Q
I
A
N
L
V
Site 32
T422
G
R
R
I
I
D
R
T
L
R
T
L
G
P
S
Site 33
T425
I
I
D
R
T
L
R
T
L
G
P
S
D
M
F
Site 34
S429
T
L
R
T
L
G
P
S
D
M
F
P
A
E
V
Site 35
S466
E
K
G
V
Q
L
D
S
A
G
L
E
R
L
A
Site 36
T510
Q
R
Q
G
V
P
P
T
D
D
S
P
K
Y
N
Site 37
S513
G
V
P
P
T
D
D
S
P
K
Y
N
Y
S
L
Site 38
Y516
P
T
D
D
S
P
K
Y
N
Y
S
L
R
P
S
Site 39
S519
D
S
P
K
Y
N
Y
S
L
R
P
S
G
S
Y
Site 40
S523
Y
N
Y
S
L
R
P
S
G
S
Y
E
F
G
T
Site 41
S525
Y
S
L
R
P
S
G
S
Y
E
F
G
T
C
E
Site 42
Y526
S
L
R
P
S
G
S
Y
E
F
G
T
C
E
A
Site 43
T530
S
G
S
Y
E
F
G
T
C
E
A
Q
V
L
Q
Site 44
Y539
E
A
Q
V
L
Q
L
Y
T
E
D
G
T
A
V
Site 45
T544
Q
L
Y
T
E
D
G
T
A
V
A
S
V
G
K
Site 46
S548
E
D
G
T
A
V
A
S
V
G
K
G
Q
R
C
Site 47
T562
C
G
L
L
L
D
R
T
N
F
Y
A
E
Q
G
Site 48
Y565
L
L
D
R
T
N
F
Y
A
E
Q
G
G
Q
A
Site 49
S573
A
E
Q
G
G
Q
A
S
D
R
G
Y
L
V
R
Site 50
Y577
G
Q
A
S
D
R
G
Y
L
V
R
A
G
Q
E
Site 51
T645
L
N
W
A
L
R
Q
T
L
G
P
G
T
E
Q
Site 52
T650
R
Q
T
L
G
P
G
T
E
Q
Q
G
S
H
L
Site 53
S655
P
G
T
E
Q
Q
G
S
H
L
N
P
E
Q
L
Site 54
T668
Q
L
R
L
D
V
T
T
Q
T
P
L
T
P
E
Site 55
T670
R
L
D
V
T
T
Q
T
P
L
T
P
E
Q
L
Site 56
T673
V
T
T
Q
T
P
L
T
P
E
Q
L
R
A
V
Site 57
T683
Q
L
R
A
V
E
N
T
V
Q
E
A
V
G
Q
Site 58
S712
A
Q
V
P
G
L
R
S
L
D
E
V
Y
P
D
Site 59
Y717
L
R
S
L
D
E
V
Y
P
D
P
V
R
V
V
Site 60
S738
A
H
A
L
D
P
A
S
Q
A
A
L
Q
T
S
Site 61
S772
I
I
G
D
R
Q
L
S
K
G
T
T
R
L
L
Site 62
S795
Q
A
R
E
L
G
Q
S
L
A
Q
E
V
K
A
Site 63
T804
A
Q
E
V
K
A
A
T
E
R
L
S
L
G
S
Site 64
S808
K
A
A
T
E
R
L
S
L
G
S
R
D
V
A
Site 65
S811
T
E
R
L
S
L
G
S
R
D
V
A
E
A
L
Site 66
T833
R
L
I
E
A
V
E
T
A
V
M
P
Q
W
Q
Site 67
T847
Q
R
R
E
L
L
A
T
V
K
M
L
Q
R
R
Site 68
T857
M
L
Q
R
R
A
N
T
A
I
R
K
L
Q
M
Site 69
S879
Q
E
L
L
E
R
H
S
K
G
P
L
I
V
D
Site 70
S892
V
D
T
V
S
A
E
S
L
S
V
L
V
K
V
Site 71
S894
T
V
S
A
E
S
L
S
V
L
V
K
V
V
R
Site 72
S957
M
G
G
K
A
W
G
S
R
V
V
A
Q
G
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation