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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SPIN3
Full Name:
Spindlin-3
Alias:
Spindlin-like protein 3
Type:
Nucleus, Cytoplasm protein
Mass (Da):
29207
Number AA:
258
UniProt ID:
Q5JUX0
International Prot ID:
IPI00174535
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0007276
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
K
A
A
A
G
Q
R
S
R
T
G
A
G
H
G
Site 2
T16
A
A
G
Q
R
S
R
T
G
A
G
H
G
S
V
Site 3
S22
R
T
G
A
G
H
G
S
V
S
V
T
M
I
K
Site 4
S24
G
A
G
H
G
S
V
S
V
T
M
I
K
R
K
Site 5
T26
G
H
G
S
V
S
V
T
M
I
K
R
K
A
A
Site 6
S39
A
A
H
K
K
H
R
S
R
P
T
S
Q
P
R
Site 7
T42
K
K
H
R
S
R
P
T
S
Q
P
R
G
N
I
Site 8
S43
K
H
R
S
R
P
T
S
Q
P
R
G
N
I
V
Site 9
T66
K
D
G
D
E
P
L
T
Q
W
K
G
T
V
L
Site 10
Y94
Y
D
G
F
D
C
V
Y
G
L
E
L
H
R
D
Site 11
S105
L
H
R
D
E
R
V
S
S
L
E
V
L
P
N
Site 12
S106
H
R
D
E
R
V
S
S
L
E
V
L
P
N
R
Site 13
S116
V
L
P
N
R
V
A
S
S
R
I
S
D
T
H
Site 14
S120
R
V
A
S
S
R
I
S
D
T
H
L
A
E
I
Site 15
Y173
Y
E
K
D
P
V
L
Y
M
Y
Q
L
L
D
D
Site 16
Y175
K
D
P
V
L
Y
M
Y
Q
L
L
D
D
Y
K
Site 17
Y181
M
Y
Q
L
L
D
D
Y
K
D
G
D
L
R
I
Site 18
S192
D
L
R
I
L
Q
D
S
N
D
S
P
L
A
E
Site 19
S195
I
L
Q
D
S
N
D
S
P
L
A
E
R
E
P
Site 20
S208
E
P
G
E
V
I
D
S
L
V
G
K
Q
V
E
Site 21
Y216
L
V
G
K
Q
V
E
Y
A
K
D
D
G
S
K
Site 22
S222
E
Y
A
K
D
D
G
S
K
R
T
G
M
V
I
Site 23
Y239
V
E
A
K
P
S
V
Y
F
I
K
F
D
D
D
Site 24
Y250
F
D
D
D
F
H
I
Y
V
Y
D
L
V
K
T
Site 25
Y252
D
D
F
H
I
Y
V
Y
D
L
V
K
T
S
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation