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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EFHC1
Full Name:
EF-hand domain-containing protein 1
Alias:
Myoclonin-1
Type:
Mass (Da):
73990
Number AA:
640
UniProt ID:
Q5JVL4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
G
L
P
F
L
P
G
T
S
F
K
D
S
T
K
Site 2
S16
L
P
F
L
P
G
T
S
F
K
D
S
T
K
T
Site 3
S20
P
G
T
S
F
K
D
S
T
K
T
A
F
H
R
Site 4
T23
S
F
K
D
S
T
K
T
A
F
H
R
S
Q
T
Site 5
S28
T
K
T
A
F
H
R
S
Q
T
L
S
Y
R
N
Site 6
T30
T
A
F
H
R
S
Q
T
L
S
Y
R
N
G
Y
Site 7
S32
F
H
R
S
Q
T
L
S
Y
R
N
G
Y
A
I
Site 8
Y37
T
L
S
Y
R
N
G
Y
A
I
V
R
R
P
T
Site 9
T44
Y
A
I
V
R
R
P
T
V
G
I
G
G
D
R
Site 10
S58
R
L
Q
F
N
Q
L
S
Q
A
E
L
D
E
L
Site 11
Y74
S
K
A
P
V
L
T
Y
G
Q
P
K
Q
A
P
Site 12
Y102
K
V
L
K
F
D
A
Y
F
Q
E
D
V
P
M
Site 13
S110
F
Q
E
D
V
P
M
S
T
E
E
Q
Y
R
I
Site 14
T111
Q
E
D
V
P
M
S
T
E
E
Q
Y
R
I
R
Site 15
Y115
P
M
S
T
E
E
Q
Y
R
I
R
Q
V
N
I
Site 16
Y123
R
I
R
Q
V
N
I
Y
Y
Y
L
E
D
D
S
Site 17
Y125
R
Q
V
N
I
Y
Y
Y
L
E
D
D
S
M
S
Site 18
S130
Y
Y
Y
L
E
D
D
S
M
S
V
I
E
P
V
Site 19
S132
Y
L
E
D
D
S
M
S
V
I
E
P
V
V
E
Site 20
Y163
K
N
D
R
G
D
H
Y
H
W
K
D
L
N
R
Site 21
T175
L
N
R
G
I
N
I
T
I
Y
G
K
T
F
R
Site 22
S196
F
T
Q
V
F
L
E
S
Q
G
I
E
L
N
P
Site 23
Y212
E
K
M
A
L
D
P
Y
T
E
L
R
K
Q
P
Site 24
T213
K
M
A
L
D
P
Y
T
E
L
R
K
Q
P
L
Site 25
Y223
R
K
Q
P
L
R
K
Y
V
T
P
S
D
F
D
Site 26
T225
Q
P
L
R
K
Y
V
T
P
S
D
F
D
Q
L
Site 27
T237
D
Q
L
K
Q
F
L
T
F
D
K
Q
V
L
R
Site 28
Y246
D
K
Q
V
L
R
F
Y
A
I
W
D
D
T
D
Site 29
Y256
W
D
D
T
D
S
M
Y
G
E
C
R
T
Y
I
Site 30
Y267
R
T
Y
I
I
H
Y
Y
L
M
D
D
T
V
E
Site 31
S316
P
Q
C
V
L
E
I
S
D
Q
E
V
L
E
W
Site 32
T341
S
L
T
I
L
G
R
T
F
F
I
Y
D
C
D
Site 33
Y345
L
G
R
T
F
F
I
Y
D
C
D
P
F
T
R
Site 34
T351
I
Y
D
C
D
P
F
T
R
R
Y
Y
K
E
K
Site 35
Y354
C
D
P
F
T
R
R
Y
Y
K
E
K
F
G
I
Site 36
Y355
D
P
F
T
R
R
Y
Y
K
E
K
F
G
I
T
Site 37
S370
D
L
P
R
I
D
V
S
K
R
E
P
P
P
V
Site 38
Y384
V
K
Q
E
L
P
P
Y
N
G
F
G
L
V
E
Site 39
Y422
N
D
N
K
V
L
R
Y
L
A
V
L
E
S
P
Site 40
S428
R
Y
L
A
V
L
E
S
P
I
P
E
D
K
D
Site 41
S441
K
D
R
R
F
V
F
S
Y
F
L
A
T
D
M
Site 42
S459
F
E
P
P
V
R
N
S
G
I
I
G
G
K
Y
Site 43
T470
G
G
K
Y
L
G
R
T
K
V
V
K
P
Y
S
Site 44
S477
T
K
V
V
K
P
Y
S
T
V
D
N
P
V
Y
Site 45
T478
K
V
V
K
P
Y
S
T
V
D
N
P
V
Y
Y
Site 46
Y484
S
T
V
D
N
P
V
Y
Y
G
P
S
D
F
F
Site 47
T508
H
R
F
I
I
L
D
T
D
E
Y
V
L
K
Y
Site 48
Y511
I
I
L
D
T
D
E
Y
V
L
K
Y
M
E
S
Site 49
Y515
T
D
E
Y
V
L
K
Y
M
E
S
N
A
A
Q
Site 50
S518
Y
V
L
K
Y
M
E
S
N
A
A
Q
Y
S
P
Site 51
S524
E
S
N
A
A
Q
Y
S
P
E
A
L
A
S
I
Site 52
S530
Y
S
P
E
A
L
A
S
I
Q
N
H
V
R
K
Site 53
T550
P
E
A
E
S
K
Q
T
E
K
D
P
G
V
Q
Site 54
T565
E
L
E
A
L
I
D
T
I
Q
K
Q
L
K
D
Site 55
Y586
I
R
E
A
F
Q
I
Y
D
K
E
A
S
G
Y
Site 56
Y593
Y
D
K
E
A
S
G
Y
V
D
R
D
M
F
F
Site 57
S623
K
E
L
I
R
M
C
S
H
G
E
G
K
I
N
Site 58
Y631
H
G
E
G
K
I
N
Y
Y
N
F
V
R
A
F
Site 59
Y632
G
E
G
K
I
N
Y
Y
N
F
V
R
A
F
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation