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Updated November 2019
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Protein Info
Short Name:
C6orf186
Full Name:
UPF0624 protein C6orf186
Alias:
Type:
Mass (Da):
41330
Number AA:
366
UniProt ID:
Q5JXM2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S40
L
R
R
A
G
P
G
S
P
T
R
S
A
P
P
Site 2
T42
R
A
G
P
G
S
P
T
R
S
A
P
P
G
P
Site 3
S44
G
P
G
S
P
T
R
S
A
P
P
G
P
A
W
Site 4
S69
P
G
Q
P
R
G
A
S
R
R
Q
V
T
Y
V
Site 5
T74
G
A
S
R
R
Q
V
T
Y
V
R
S
G
R
R
Site 6
Y75
A
S
R
R
Q
V
T
Y
V
R
S
G
R
R
A
Site 7
S78
R
Q
V
T
Y
V
R
S
G
R
R
A
P
P
G
Site 8
S89
A
P
P
G
G
G
G
S
G
T
P
E
P
G
C
Site 9
T91
P
G
G
G
G
S
G
T
P
E
P
G
C
C
A
Site 10
S123
P
W
A
G
S
A
Q
S
L
D
E
E
A
W
R
Site 11
S149
C
N
H
M
N
T
D
S
L
A
T
D
S
S
P
Site 12
S154
T
D
S
L
A
T
D
S
S
P
T
H
K
P
W
Site 13
S155
D
S
L
A
T
D
S
S
P
T
H
K
P
W
S
Site 14
Y183
R
N
K
Q
C
R
L
Y
S
L
G
L
G
S
D
Site 15
S184
N
K
Q
C
R
L
Y
S
L
G
L
G
S
D
D
Site 16
S189
L
Y
S
L
G
L
G
S
D
D
T
H
F
E
V
Site 17
T192
L
G
L
G
S
D
D
T
H
F
E
V
S
M
A
Site 18
S211
E
V
H
R
F
D
P
S
V
K
S
A
H
I
L
Site 19
S214
R
F
D
P
S
V
K
S
A
H
I
L
E
S
Q
Site 20
Y225
L
E
S
Q
H
L
W
Y
H
R
L
S
I
D
W
Site 21
S246
V
A
A
Q
K
P
H
S
N
T
R
K
L
G
S
Site 22
S253
S
N
T
R
K
L
G
S
I
L
N
E
F
G
H
Site 23
S307
H
W
P
G
F
E
V
S
G
S
D
S
S
V
V
Site 24
S309
P
G
F
E
V
S
G
S
D
S
S
V
V
R
F
Site 25
S311
F
E
V
S
G
S
D
S
S
V
V
R
F
W
Y
Site 26
S312
E
V
S
G
S
D
S
S
V
V
R
F
W
Y
S
Site 27
Y318
S
S
V
V
R
F
W
Y
S
L
L
K
E
L
E
Site 28
S319
S
V
V
R
F
W
Y
S
L
L
K
E
L
E
Q
Site 29
S334
K
D
F
R
L
F
H
S
Y
K
D
L
S
K
P
Site 30
Y335
D
F
R
L
F
H
S
Y
K
D
L
S
K
P
Q
Site 31
S339
F
H
S
Y
K
D
L
S
K
P
Q
L
F
L
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation