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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RNFT1
Full Name:
RING finger and transmembrane domain-containing protein 1
Alias:
Protein PTD016
Type:
Mass (Da):
49710
Number AA:
435
UniProt ID:
Q5M7Z0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
L
S
L
P
T
P
P
S
A
S
G
H
E
R
R
Site 2
T27
R
Q
R
P
E
A
K
T
S
G
S
E
K
K
Y
Site 3
S28
Q
R
P
E
A
K
T
S
G
S
E
K
K
Y
L
Site 4
S30
P
E
A
K
T
S
G
S
E
K
K
Y
L
R
A
Site 5
Y34
T
S
G
S
E
K
K
Y
L
R
A
M
Q
A
N
Site 6
S43
R
A
M
Q
A
N
R
S
Q
L
H
S
P
P
G
Site 7
S47
A
N
R
S
Q
L
H
S
P
P
G
T
G
S
S
Site 8
T51
Q
L
H
S
P
P
G
T
G
S
S
E
D
A
S
Site 9
S53
H
S
P
P
G
T
G
S
S
E
D
A
S
T
P
Site 10
S54
S
P
P
G
T
G
S
S
E
D
A
S
T
P
Q
Site 11
S58
T
G
S
S
E
D
A
S
T
P
Q
C
V
H
T
Site 12
T59
G
S
S
E
D
A
S
T
P
Q
C
V
H
T
R
Site 13
T68
Q
C
V
H
T
R
L
T
G
E
G
S
C
P
H
Site 14
S72
T
R
L
T
G
E
G
S
C
P
H
S
G
D
V
Site 15
S76
G
E
G
S
C
P
H
S
G
D
V
H
I
Q
I
Site 16
S95
K
E
C
A
E
N
A
S
S
R
N
I
R
S
G
Site 17
S96
E
C
A
E
N
A
S
S
R
N
I
R
S
G
V
Site 18
S101
A
S
S
R
N
I
R
S
G
V
H
S
C
A
H
Site 19
S119
H
S
R
L
R
G
H
S
H
S
E
A
R
L
T
Site 20
S121
R
L
R
G
H
S
H
S
E
A
R
L
T
D
D
Site 21
T126
S
H
S
E
A
R
L
T
D
D
T
A
A
E
S
Site 22
T129
E
A
R
L
T
D
D
T
A
A
E
S
G
D
H
Site 23
S133
T
D
D
T
A
A
E
S
G
D
H
G
S
S
S
Site 24
S138
A
E
S
G
D
H
G
S
S
S
F
S
E
F
R
Site 25
S139
E
S
G
D
H
G
S
S
S
F
S
E
F
R
Y
Site 26
S140
S
G
D
H
G
S
S
S
F
S
E
F
R
Y
L
Site 27
S142
D
H
G
S
S
S
F
S
E
F
R
Y
L
F
K
Site 28
Y146
S
S
F
S
E
F
R
Y
L
F
K
W
L
Q
K
Site 29
S200
Q
V
F
L
R
E
R
S
S
K
I
Q
C
A
W
Site 30
S201
V
F
L
R
E
R
S
S
K
I
Q
C
A
W
L
Site 31
Y220
A
G
S
S
V
L
L
Y
Y
T
F
H
S
Q
S
Site 32
S231
H
S
Q
S
L
Y
Y
S
L
I
F
L
N
P
T
Site 33
Y296
L
E
E
L
C
Q
Y
Y
R
T
F
V
P
I
P
Site 34
Y312
W
F
R
Y
L
I
S
Y
G
E
F
G
N
V
T
Site 35
T345
E
F
F
G
H
L
R
T
F
R
Q
V
L
R
I
Site 36
Y359
I
F
F
T
Q
P
S
Y
G
V
A
A
S
K
R
Site 37
S364
P
S
Y
G
V
A
A
S
K
R
Q
C
S
D
V
Site 38
S369
A
A
S
K
R
Q
C
S
D
V
D
D
I
C
S
Site 39
T428
N
K
W
K
D
G
A
T
S
S
H
L
Q
I
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation