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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WIPI1
Full Name:
WD repeat domain phosphoinositide-interacting protein 1
Alias:
Atg18 protein homolog;WD40 repeat protein interacting with phosphoinositides of 49 kDa
Type:
Mass (Da):
48673
Number AA:
446
UniProt ID:
Q5MNZ9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
G
G
V
E
S
A
L
S
C
F
S
F
N
Q
D
Site 2
S21
E
S
A
L
S
C
F
S
F
N
Q
D
C
T
S
Site 3
T27
F
S
F
N
Q
D
C
T
S
L
A
T
G
T
K
Site 4
S28
S
F
N
Q
D
C
T
S
L
A
T
G
T
K
A
Site 5
Y37
A
T
G
T
K
A
G
Y
K
L
F
S
L
S
S
Site 6
S41
K
A
G
Y
K
L
F
S
L
S
S
V
E
Q
L
Site 7
S43
G
Y
K
L
F
S
L
S
S
V
E
Q
L
D
Q
Site 8
S44
Y
K
L
F
S
L
S
S
V
E
Q
L
D
Q
V
Site 9
Y61
S
N
E
I
P
D
V
Y
I
V
E
R
L
F
S
Site 10
S76
S
S
L
V
V
V
V
S
H
T
K
P
R
Q
M
Site 11
Y86
K
P
R
Q
M
N
V
Y
H
F
K
K
G
T
E
Site 12
Y97
K
G
T
E
I
C
N
Y
S
Y
S
S
N
I
L
Site 13
S98
G
T
E
I
C
N
Y
S
Y
S
S
N
I
L
S
Site 14
Y99
T
E
I
C
N
Y
S
Y
S
S
N
I
L
S
I
Site 15
S100
E
I
C
N
Y
S
Y
S
S
N
I
L
S
I
R
Site 16
S105
S
Y
S
S
N
I
L
S
I
R
L
N
R
Q
R
Site 17
T134
K
D
M
K
L
L
K
T
L
L
D
I
P
A
N
Site 18
T143
L
D
I
P
A
N
P
T
G
L
C
A
L
S
I
Site 19
S149
P
T
G
L
C
A
L
S
I
N
H
S
N
S
Y
Site 20
S153
C
A
L
S
I
N
H
S
N
S
Y
L
A
Y
P
Site 21
S155
L
S
I
N
H
S
N
S
Y
L
A
Y
P
G
S
Site 22
Y156
S
I
N
H
S
N
S
Y
L
A
Y
P
G
S
L
Site 23
Y159
H
S
N
S
Y
L
A
Y
P
G
S
L
T
S
G
Site 24
Y171
T
S
G
E
I
V
L
Y
D
G
N
S
L
K
T
Site 25
T178
Y
D
G
N
S
L
K
T
V
C
T
I
A
A
H
Site 26
T193
E
G
T
L
A
A
I
T
F
N
A
S
G
S
K
Site 27
S199
I
T
F
N
A
S
G
S
K
L
A
S
A
S
E
Site 28
S203
A
S
G
S
K
L
A
S
A
S
E
K
G
T
V
Site 29
S205
G
S
K
L
A
S
A
S
E
K
G
T
V
I
R
Site 30
Y223
V
P
D
G
Q
K
L
Y
E
F
R
R
G
M
K
Site 31
Y232
F
R
R
G
M
K
R
Y
V
T
I
S
S
L
V
Site 32
T255
C
A
S
S
N
T
E
T
V
H
I
F
K
L
E
Site 33
S267
K
L
E
Q
V
T
N
S
R
P
E
E
P
S
T
Site 34
S273
N
S
R
P
E
E
P
S
T
W
S
G
Y
M
G
Site 35
T274
S
R
P
E
E
P
S
T
W
S
G
Y
M
G
K
Site 36
T319
S
G
Q
R
N
I
C
T
L
S
T
I
Q
K
L
Site 37
S321
Q
R
N
I
C
T
L
S
T
I
Q
K
L
P
R
Site 38
T322
R
N
I
C
T
L
S
T
I
Q
K
L
P
R
L
Site 39
S335
R
L
L
V
A
S
S
S
G
H
L
Y
M
Y
N
Site 40
Y339
A
S
S
S
G
H
L
Y
M
Y
N
L
D
P
Q
Site 41
Y341
S
S
G
H
L
Y
M
Y
N
L
D
P
Q
D
G
Site 42
S362
K
T
H
S
L
L
G
S
G
T
T
E
E
N
K
Site 43
S376
K
E
N
D
L
R
P
S
L
P
Q
S
Y
A
A
Site 44
S380
L
R
P
S
L
P
Q
S
Y
A
A
T
V
A
R
Site 45
T384
L
P
Q
S
Y
A
A
T
V
A
R
P
S
A
S
Site 46
S391
T
V
A
R
P
S
A
S
S
A
S
T
V
P
G
Site 47
S392
V
A
R
P
S
A
S
S
A
S
T
V
P
G
Y
Site 48
S394
R
P
S
A
S
S
A
S
T
V
P
G
Y
S
E
Site 49
T395
P
S
A
S
S
A
S
T
V
P
G
Y
S
E
D
Site 50
Y399
S
A
S
T
V
P
G
Y
S
E
D
G
G
A
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation