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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA1904
Full Name:
Leucine-rich repeat and fibronectin type-III domain-containing protein 6
Alias:
DJ63G5.3; Extracellular leucine-rich repeat and fibronectin type III domain containing 2; Extracellular leucine-rich repeat and fibronectin type III domain-containing protein 2; Leucine-rich repeat and fibronectin type-III domain-containing protein 6; Leucine-rich repeat-containing protein 62; LRFN6; LRRC62
Type:
Membrane protein, integral
Mass (Da):
89687
Number AA:
820
UniProt ID:
Q5R3F8
International Prot ID:
IPI00289849
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0009986
GO:0016021
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y72
N
K
L
K
A
V
L
Y
S
S
L
N
R
F
G
Site 2
Y210
F
N
N
V
T
K
N
Y
D
R
L
Q
C
E
S
Site 3
Y224
S
P
R
E
F
A
G
Y
P
L
L
V
P
R
P
Site 4
Y232
P
L
L
V
P
R
P
Y
H
S
L
N
A
I
T
Site 5
S431
M
Q
E
E
K
Q
K
S
V
N
V
K
K
T
I
Site 6
S472
L
P
V
S
R
M
A
S
I
P
S
M
I
G
E
Site 7
S475
S
R
M
A
S
I
P
S
M
I
G
E
K
L
P
Site 8
T483
M
I
G
E
K
L
P
T
A
K
G
L
E
A
G
Site 9
T493
G
L
E
A
G
L
D
T
P
K
V
A
T
K
G
Site 10
Y502
K
V
A
T
K
G
N
Y
I
E
V
R
T
G
A
Site 11
S567
A
S
F
L
G
G
G
S
S
S
G
D
P
E
L
Site 12
S568
S
F
L
G
G
G
S
S
S
G
D
P
E
L
A
Site 13
S569
F
L
G
G
G
S
S
S
G
D
P
E
L
A
F
Site 14
S600
P
G
A
L
E
R
P
S
F
L
S
P
P
Y
K
Site 15
S603
L
E
R
P
S
F
L
S
P
P
Y
K
E
S
S
Site 16
Y606
P
S
F
L
S
P
P
Y
K
E
S
S
H
H
P
Site 17
S609
L
S
P
P
Y
K
E
S
S
H
H
P
L
Q
R
Site 18
S610
S
P
P
Y
K
E
S
S
H
H
P
L
Q
R
Q
Site 19
S619
H
P
L
Q
R
Q
L
S
A
D
A
A
V
T
R
Site 20
T628
D
A
A
V
T
R
K
T
C
S
V
S
S
S
G
Site 21
S630
A
V
T
R
K
T
C
S
V
S
S
S
G
S
I
Site 22
S632
T
R
K
T
C
S
V
S
S
S
G
S
I
K
S
Site 23
S634
K
T
C
S
V
S
S
S
G
S
I
K
S
A
K
Site 24
S639
S
S
S
G
S
I
K
S
A
K
V
F
S
L
D
Site 25
S644
I
K
S
A
K
V
F
S
L
D
V
P
D
H
P
Site 26
T654
V
P
D
H
P
A
A
T
G
L
A
K
G
D
S
Site 27
S661
T
G
L
A
K
G
D
S
K
Y
I
E
K
G
S
Site 28
Y663
L
A
K
G
D
S
K
Y
I
E
K
G
S
P
L
Site 29
S668
S
K
Y
I
E
K
G
S
P
L
N
S
P
L
D
Site 30
S672
E
K
G
S
P
L
N
S
P
L
D
R
L
P
L
Site 31
S688
P
A
G
S
G
G
G
S
G
G
G
G
G
I
H
Site 32
Y703
H
L
E
V
K
P
A
Y
H
C
S
E
H
R
H
Site 33
Y716
R
H
S
F
P
A
L
Y
Y
E
E
G
A
D
S
Site 34
Y717
H
S
F
P
A
L
Y
Y
E
E
G
A
D
S
L
Site 35
S723
Y
Y
E
E
G
A
D
S
L
S
Q
R
V
S
F
Site 36
S725
E
E
G
A
D
S
L
S
Q
R
V
S
F
L
K
Site 37
S729
D
S
L
S
Q
R
V
S
F
L
K
P
L
T
R
Site 38
T735
V
S
F
L
K
P
L
T
R
S
K
R
D
S
T
Site 39
S737
F
L
K
P
L
T
R
S
K
R
D
S
T
Y
S
Site 40
S741
L
T
R
S
K
R
D
S
T
Y
S
Q
L
S
P
Site 41
T742
T
R
S
K
R
D
S
T
Y
S
Q
L
S
P
R
Site 42
Y743
R
S
K
R
D
S
T
Y
S
Q
L
S
P
R
H
Site 43
S744
S
K
R
D
S
T
Y
S
Q
L
S
P
R
H
Y
Site 44
S747
D
S
T
Y
S
Q
L
S
P
R
H
Y
Y
S
G
Site 45
Y751
S
Q
L
S
P
R
H
Y
Y
S
G
Y
S
S
S
Site 46
Y752
Q
L
S
P
R
H
Y
Y
S
G
Y
S
S
S
P
Site 47
S753
L
S
P
R
H
Y
Y
S
G
Y
S
S
S
P
E
Site 48
Y755
P
R
H
Y
Y
S
G
Y
S
S
S
P
E
Y
S
Site 49
S756
R
H
Y
Y
S
G
Y
S
S
S
P
E
Y
S
S
Site 50
S757
H
Y
Y
S
G
Y
S
S
S
P
E
Y
S
S
E
Site 51
S758
Y
Y
S
G
Y
S
S
S
P
E
Y
S
S
E
S
Site 52
Y761
G
Y
S
S
S
P
E
Y
S
S
E
S
T
H
K
Site 53
S762
Y
S
S
S
P
E
Y
S
S
E
S
T
H
K
I
Site 54
S763
S
S
S
P
E
Y
S
S
E
S
T
H
K
I
W
Site 55
T766
P
E
Y
S
S
E
S
T
H
K
I
W
E
R
F
Site 56
Y776
I
W
E
R
F
R
P
Y
K
K
H
H
R
E
E
Site 57
Y785
K
H
H
R
E
E
V
Y
M
A
A
G
H
A
L
Site 58
Y810
D
L
H
D
I
L
D
Y
W
K
G
V
S
A
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation