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Updated November 2019
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Protein Info
Short Name:
C1orf173
Full Name:
Uncharacterized protein C1orf173
Alias:
Type:
Mass (Da):
168466
Number AA:
1530
UniProt ID:
Q5RHP9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y13
P
A
G
L
L
A
A
Y
N
S
L
M
D
K
H
Site 2
Y24
M
D
K
H
L
A
G
Y
F
N
N
T
R
I
R
Site 3
S37
I
R
R
H
L
L
R
S
G
L
I
T
R
S
G
Site 4
S43
R
S
G
L
I
T
R
S
G
R
I
L
S
E
K
Site 5
S48
T
R
S
G
R
I
L
S
E
K
E
Y
K
L
N
Site 6
Y52
R
I
L
S
E
K
E
Y
K
L
N
M
M
K
R
Site 7
Y64
M
K
R
D
H
Q
K
Y
I
R
E
C
L
A
Q
Site 8
Y83
K
V
L
D
M
E
R
Y
H
Q
L
E
I
K
K
Site 9
T109
Q
R
F
K
G
E
H
T
R
R
S
V
E
N
N
Site 10
S112
K
G
E
H
T
R
R
S
V
E
N
N
M
P
I
Site 11
S121
E
N
N
M
P
I
L
S
P
H
P
P
V
G
P
Site 12
S130
H
P
P
V
G
P
K
S
N
R
G
H
S
V
L
Site 13
S135
P
K
S
N
R
G
H
S
V
L
V
D
E
G
H
Site 14
Y154
A
L
T
A
P
R
P
Y
T
A
P
G
N
M
Q
Site 15
T155
L
T
A
P
R
P
Y
T
A
P
G
N
M
Q
P
Site 16
S171
I
R
L
Q
P
L
P
S
N
P
A
V
E
T
V
Site 17
T177
P
S
N
P
A
V
E
T
V
P
K
V
T
S
R
Site 18
S183
E
T
V
P
K
V
T
S
R
S
R
S
K
T
S
Site 19
S185
V
P
K
V
T
S
R
S
R
S
K
T
S
L
L
Site 20
S187
K
V
T
S
R
S
R
S
K
T
S
L
L
E
N
Site 21
T189
T
S
R
S
R
S
K
T
S
L
L
E
N
E
A
Site 22
S190
S
R
S
R
S
K
T
S
L
L
E
N
E
A
L
Site 23
S212
A
V
M
K
F
R
N
S
I
G
N
S
Q
R
M
Site 24
S216
F
R
N
S
I
G
N
S
Q
R
M
N
S
Y
Q
Site 25
S221
G
N
S
Q
R
M
N
S
Y
Q
L
P
N
I
N
Site 26
Y222
N
S
Q
R
M
N
S
Y
Q
L
P
N
I
N
S
Site 27
Y230
Q
L
P
N
I
N
S
Y
M
M
P
I
P
P
P
Site 28
T252
T
R
E
N
R
S
E
T
W
R
R
R
R
F
R
Site 29
T261
R
R
R
R
F
R
P
T
T
A
P
N
G
L
E
Site 30
T262
R
R
R
F
R
P
T
T
A
P
N
G
L
E
P
Site 31
T272
N
G
L
E
P
L
L
T
K
D
S
R
R
I
H
Site 32
S275
E
P
L
L
T
K
D
S
R
R
I
H
K
T
S
Site 33
T281
D
S
R
R
I
H
K
T
S
L
H
S
N
A
A
Site 34
S282
S
R
R
I
H
K
T
S
L
H
S
N
A
A
I
Site 35
S302
G
K
N
V
H
L
S
S
D
N
P
D
F
R
D
Site 36
Y314
F
R
D
E
I
K
V
Y
Q
Q
H
C
G
G
E
Site 37
Y326
G
G
E
N
L
C
V
Y
K
G
K
L
L
E
K
Site 38
T335
G
K
L
L
E
K
E
T
F
Q
F
I
S
K
R
Site 39
Y368
R
L
S
S
C
C
E
Y
K
H
R
K
G
S
R
Site 40
S374
E
Y
K
H
R
K
G
S
R
L
G
G
K
R
G
Site 41
S408
M
G
L
D
K
K
P
S
L
P
K
S
R
K
E
Site 42
S412
K
K
P
S
L
P
K
S
R
K
E
K
S
T
E
Site 43
S417
P
K
S
R
K
E
K
S
T
E
K
G
E
E
L
Site 44
T418
K
S
R
K
E
K
S
T
E
K
G
E
E
L
K
Site 45
Y437
K
V
R
K
E
R
E
Y
V
I
P
K
R
N
E
Site 46
S451
E
I
K
E
N
K
T
S
V
S
A
K
F
S
A
Site 47
S453
K
E
N
K
T
S
V
S
A
K
F
S
A
Q
E
Site 48
S457
T
S
V
S
A
K
F
S
A
Q
E
I
K
T
G
Site 49
S477
T
A
V
E
E
M
T
S
K
G
K
P
G
Q
E
Site 50
Y496
D
Q
E
N
T
L
K
Y
E
Y
E
E
D
F
E
Site 51
Y498
E
N
T
L
K
Y
E
Y
E
E
D
F
E
V
D
Site 52
S513
E
E
K
Q
G
E
K
S
N
E
E
G
Q
A
D
Site 53
S529
Q
M
N
G
I
P
Q
S
P
L
D
D
K
K
D
Site 54
S544
N
L
D
P
E
K
E
S
E
T
S
S
Q
K
A
Site 55
S548
E
K
E
S
E
T
S
S
Q
K
A
P
D
A
R
Site 56
S566
K
D
E
N
D
G
C
S
E
S
E
L
E
E
D
Site 57
T579
E
D
K
Q
D
M
K
T
A
S
S
T
S
S
R
Site 58
S581
K
Q
D
M
K
T
A
S
S
T
S
S
R
S
H
Site 59
S582
Q
D
M
K
T
A
S
S
T
S
S
R
S
H
P
Site 60
T583
D
M
K
T
A
S
S
T
S
S
R
S
H
P
Y
Site 61
S584
M
K
T
A
S
S
T
S
S
R
S
H
P
Y
S
Site 62
S585
K
T
A
S
S
T
S
S
R
S
H
P
Y
S
S
Site 63
S587
A
S
S
T
S
S
R
S
H
P
Y
S
S
D
S
Site 64
S591
S
S
R
S
H
P
Y
S
S
D
S
E
D
E
S
Site 65
S592
S
R
S
H
P
Y
S
S
D
S
E
D
E
S
A
Site 66
S594
S
H
P
Y
S
S
D
S
E
D
E
S
A
V
G
Site 67
S598
S
S
D
S
E
D
E
S
A
V
G
D
R
E
A
Site 68
T607
V
G
D
R
E
A
H
T
D
S
S
T
D
E
S
Site 69
S609
D
R
E
A
H
T
D
S
S
T
D
E
S
A
R
Site 70
S610
R
E
A
H
T
D
S
S
T
D
E
S
A
R
R
Site 71
T611
E
A
H
T
D
S
S
T
D
E
S
A
R
R
S
Site 72
S614
T
D
S
S
T
D
E
S
A
R
R
S
S
S
Q
Site 73
S618
T
D
E
S
A
R
R
S
S
S
Q
E
L
S
E
Site 74
S619
D
E
S
A
R
R
S
S
S
Q
E
L
S
E
N
Site 75
S620
E
S
A
R
R
S
S
S
Q
E
L
S
E
N
D
Site 76
S624
R
S
S
S
Q
E
L
S
E
N
D
K
P
R
K
Site 77
S632
E
N
D
K
P
R
K
S
H
L
P
I
E
E
S
Site 78
S639
S
H
L
P
I
E
E
S
L
E
I
E
I
E
D
Site 79
S664
K
P
M
P
I
D
E
S
F
E
N
V
L
K
E
Site 80
S685
Q
E
I
A
E
G
L
S
E
K
S
G
K
H
V
Site 81
S688
A
E
G
L
S
E
K
S
G
K
H
V
S
A
E
Site 82
S693
E
K
S
G
K
H
V
S
A
E
E
K
E
K
D
Site 83
S702
E
E
K
E
K
D
K
S
K
L
W
E
E
S
T
Site 84
S759
A
I
N
S
N
K
E
S
Q
Q
L
V
Q
K
T
Site 85
S856
R
R
L
G
E
G
G
S
D
P
I
G
Q
A
A
Site 86
S871
A
K
D
A
V
G
L
S
K
D
E
A
P
E
K
Site 87
T884
E
K
Q
A
L
M
L
T
V
L
E
T
D
K
A
Site 88
S928
A
L
R
E
A
A
T
S
E
E
G
E
A
E
G
Site 89
S940
A
E
G
G
V
A
V
S
D
V
G
E
S
E
E
Site 90
S950
G
E
S
E
E
E
A
S
I
D
L
E
D
T
G
Site 91
T962
D
T
G
P
M
E
D
T
A
S
K
R
E
D
G
Site 92
S964
G
P
M
E
D
T
A
S
K
R
E
D
G
S
E
Site 93
S970
A
S
K
R
E
D
G
S
E
E
A
I
L
G
G
Site 94
T990
E
R
K
E
V
M
R
T
E
T
R
L
S
P
F
Site 95
T992
K
E
V
M
R
T
E
T
R
L
S
P
F
T
G
Site 96
S995
M
R
T
E
T
R
L
S
P
F
T
G
E
A
E
Site 97
T998
E
T
R
L
S
P
F
T
G
E
A
E
A
S
R
Site 98
S1004
F
T
G
E
A
E
A
S
R
M
Q
V
S
E
G
Site 99
S1009
E
A
S
R
M
Q
V
S
E
G
S
P
E
E
G
Site 100
S1012
R
M
Q
V
S
E
G
S
P
E
E
G
S
L
A
Site 101
S1017
E
G
S
P
E
E
G
S
L
A
K
E
A
F
L
Site 102
T1036
V
E
G
E
E
M
V
T
E
A
E
A
N
R
E
Site 103
T1068
R
K
A
E
R
P
K
T
S
L
R
K
T
D
S
Site 104
S1069
K
A
E
R
P
K
T
S
L
R
K
T
D
S
E
Site 105
T1073
P
K
T
S
L
R
K
T
D
S
E
R
E
E
V
Site 106
S1075
T
S
L
R
K
T
D
S
E
R
E
E
V
T
R
Site 107
T1115
E
V
R
A
E
E
E
T
K
A
P
P
N
E
M
Site 108
S1124
A
P
P
N
E
M
G
S
D
A
E
N
E
A
P
Site 109
S1138
P
V
E
A
S
E
L
S
D
N
P
G
L
L
G
Site 110
S1148
P
G
L
L
G
E
D
S
L
K
E
T
V
V
P
Site 111
T1152
G
E
D
S
L
K
E
T
V
V
P
I
F
E
A
Site 112
S1166
A
T
P
G
F
E
K
S
L
E
N
I
T
A
L
Site 113
S1183
E
G
G
G
E
R
L
S
E
A
R
D
T
E
H
Site 114
T1188
R
L
S
E
A
R
D
T
E
H
K
D
R
E
E
Site 115
S1197
H
K
D
R
E
E
L
S
S
R
E
N
R
A
L
Site 116
S1198
K
D
R
E
E
L
S
S
R
E
N
R
A
L
K
Site 117
S1250
L
A
A
K
D
H
D
S
C
A
G
L
E
G
R
Site 118
S1314
E
A
M
Q
D
R
N
S
E
G
D
G
D
M
E
Site 119
T1352
G
G
G
E
T
A
E
T
A
A
E
E
R
E
V
Site 120
S1377
T
I
A
N
K
A
S
S
F
S
D
V
A
E
E
Site 121
S1411
V
V
E
E
L
A
R
S
G
E
E
V
P
A
A
Site 122
T1433
T
T
E
A
G
V
G
T
P
G
A
L
E
R
K
Site 123
T1441
P
G
A
L
E
R
K
T
S
G
L
G
Q
E
Q
Site 124
S1442
G
A
L
E
R
K
T
S
G
L
G
Q
E
Q
E
Site 125
T1468
S
G
D
G
R
Q
E
T
G
A
A
E
K
F
R
Site 126
S1479
E
K
F
R
L
G
L
S
R
E
G
E
R
E
L
Site 127
S1487
R
E
G
E
R
E
L
S
P
E
S
L
Q
A
M
Site 128
S1490
E
R
E
L
S
P
E
S
L
Q
A
M
A
T
L
Site 129
T1496
E
S
L
Q
A
M
A
T
L
P
V
K
P
D
F
Site 130
T1504
L
P
V
K
P
D
F
T
E
T
R
E
K
Q
Q
Site 131
T1520
M
V
Q
G
E
S
E
T
A
D
V
S
P
N
N
Site 132
S1524
E
S
E
T
A
D
V
S
P
N
N
V
Q
V
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation