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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PPM1L
Full Name:
Protein phosphatase 1L
Alias:
Protein phosphatase 1-like;Protein phosphatase 2C isoform epsilon
Type:
Mass (Da):
41053
Number AA:
360
UniProt ID:
Q5SGD2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T47
F
H
T
D
E
V
K
T
I
V
K
S
S
R
D
Site 2
S51
E
V
K
T
I
V
K
S
S
R
D
A
V
K
M
Site 3
S83
D
V
L
E
A
E
F
S
K
T
W
E
F
K
N
Site 4
T85
L
E
A
E
F
S
K
T
W
E
F
K
N
H
N
Site 5
T113
E
D
R
F
E
V
L
T
D
L
A
N
K
T
H
Site 6
Y138
G
G
E
T
A
A
E
Y
V
K
S
R
L
P
E
Site 7
S141
T
A
A
E
Y
V
K
S
R
L
P
E
A
L
K
Site 8
Y154
L
K
Q
H
L
Q
D
Y
E
K
D
K
E
N
S
Site 9
Y165
K
E
N
S
V
L
S
Y
Q
T
I
L
E
Q
Q
Site 10
S175
I
L
E
Q
Q
I
L
S
I
D
R
E
M
L
E
Site 11
T185
R
E
M
L
E
K
L
T
V
S
Y
D
E
A
G
Site 12
S187
M
L
E
K
L
T
V
S
Y
D
E
A
G
T
T
Site 13
Y188
L
E
K
L
T
V
S
Y
D
E
A
G
T
T
C
Site 14
T206
L
L
S
D
K
D
L
T
V
A
N
V
G
D
S
Site 15
S228
D
G
N
A
I
P
L
S
H
D
H
K
P
Y
Q
Site 16
S250
K
R
A
G
G
F
I
S
F
N
G
S
W
R
V
Site 17
Y270
M
S
R
S
L
G
D
Y
P
L
K
N
L
N
V
Site 18
T286
I
P
D
P
D
I
L
T
F
D
L
D
K
L
Q
Site 19
S309
D
G
L
W
D
A
F
S
N
E
E
A
V
R
F
Site 20
S330
E
P
H
F
G
A
K
S
I
V
L
Q
S
F
Y
Site 21
S335
A
K
S
I
V
L
Q
S
F
Y
R
G
C
P
D
Site 22
S354
M
V
V
K
F
R
N
S
S
K
T
E
E
Q
_
Site 23
S355
V
V
K
F
R
N
S
S
K
T
E
E
Q
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation