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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LDLRAP1
Full Name:
Low density lipoprotein receptor adapter protein 1
Alias:
ARH; ARH1; ARH2; Autosomal recessive hypercholesterolemia protein; DKFZp586D0624; FHCB1; FHCB2; Low density lipoprotein receptor adaptor protein 1; MGC34705
Type:
Mass (Da):
33885
Number AA:
308
UniProt ID:
Q5SW96
International Prot ID:
IPI00004758
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0009925
GO:0005829
GO:0005769
Uniprot
OncoNet
Molecular Function:
GO:0030276
GO:0001784
GO:0008022
PhosphoSite+
KinaseNET
Biological Process:
GO:0042632
GO:0008203
GO:0006897
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
A
G
R
A
L
I
R
S
P
S
L
A
K
Q
S
Site 2
S16
R
A
L
I
R
S
P
S
L
A
K
Q
S
W
G
Site 3
S21
S
P
S
L
A
K
Q
S
W
G
G
G
G
R
H
Site 4
T36
R
K
L
P
E
N
W
T
D
T
R
E
T
L
L
Site 5
T38
L
P
E
N
W
T
D
T
R
E
T
L
L
E
G
Site 6
T41
N
W
T
D
T
R
E
T
L
L
E
G
M
L
F
Site 7
T56
S
L
K
Y
L
G
M
T
L
V
E
Q
P
K
G
Site 8
S67
Q
P
K
G
E
E
L
S
A
A
A
I
K
R
I
Site 9
T89
G
K
K
L
Q
K
V
T
L
K
V
S
P
R
G
Site 10
T100
S
P
R
G
I
I
L
T
D
N
L
T
N
Q
L
Site 11
Y118
V
S
I
Y
R
I
S
Y
C
T
A
D
K
M
H
Site 12
Y131
M
H
D
K
V
F
A
Y
I
A
Q
S
Q
H
N
Site 13
S135
V
F
A
Y
I
A
Q
S
Q
H
N
Q
S
L
E
Site 14
S140
A
Q
S
Q
H
N
Q
S
L
E
C
H
A
F
L
Site 15
S175
A
F
E
F
W
Q
V
S
K
E
E
K
E
K
R
Site 16
S186
K
E
K
R
D
K
A
S
Q
E
G
G
D
V
L
Site 17
T200
L
G
A
R
Q
D
C
T
P
S
L
K
S
L
V
Site 18
S202
A
R
Q
D
C
T
P
S
L
K
S
L
V
A
T
Site 19
S224
E
T
A
K
A
P
L
S
T
V
S
A
N
T
T
Site 20
T231
S
T
V
S
A
N
T
T
N
M
D
E
V
P
R
Site 21
S243
V
P
R
P
Q
A
L
S
G
S
S
V
V
W
E
Site 22
S260
D
G
L
D
E
A
F
S
R
L
A
Q
S
R
T
Site 23
T267
S
R
L
A
Q
S
R
T
N
P
Q
V
L
D
T
Site 24
S297
V
D
W
D
K
P
D
S
S
G
T
E
Q
D
D
Site 25
S298
D
W
D
K
P
D
S
S
G
T
E
Q
D
D
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation