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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF678
Full Name:
Zinc finger protein 678
Alias:
Type:
Mass (Da):
61411
Number AA:
525
UniProt ID:
Q5SXM1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T18
C
A
F
E
G
A
N
T
S
T
S
F
Y
K
L
Site 2
S19
A
F
E
G
A
N
T
S
T
S
F
Y
K
L
V
Site 3
S21
E
G
A
N
T
S
T
S
F
Y
K
L
V
Y
T
Site 4
T52
K
D
L
C
Q
K
V
T
L
T
R
H
R
S
W
Site 5
T54
L
C
Q
K
V
T
L
T
R
H
R
S
W
G
L
Site 6
S58
V
T
L
T
R
H
R
S
W
G
L
D
N
L
H
Site 7
T72
H
L
V
K
D
W
R
T
V
N
E
G
K
G
Q
Site 8
Y82
E
G
K
G
Q
K
E
Y
C
N
R
L
T
Q
C
Site 9
T87
K
E
Y
C
N
R
L
T
Q
C
S
S
T
K
S
Site 10
S90
C
N
R
L
T
Q
C
S
S
T
K
S
K
I
F
Site 11
S91
N
R
L
T
Q
C
S
S
T
K
S
K
I
F
Q
Site 12
S107
I
E
C
G
R
N
F
S
W
R
S
I
L
T
E
Site 13
T120
T
E
H
K
R
I
H
T
G
E
K
P
Y
K
C
Site 14
S138
G
K
V
F
N
R
C
S
N
L
T
K
H
K
R
Site 15
T148
T
K
H
K
R
I
H
T
G
E
K
P
Y
K
C
Site 16
Y153
I
H
T
G
E
K
P
Y
K
C
D
E
C
G
K
Site 17
T176
T
N
H
K
K
I
H
T
G
E
K
P
Y
K
C
Site 18
S204
T
S
H
K
K
I
H
S
G
E
K
P
Y
P
C
Site 19
Y209
I
H
S
G
E
K
P
Y
P
C
E
E
C
G
K
Site 20
S222
G
K
A
F
T
Q
F
S
N
L
T
Q
H
K
R
Site 21
T232
T
Q
H
K
R
I
H
T
G
E
K
P
Y
K
C
Site 22
T288
T
R
H
R
R
I
H
T
G
E
K
P
Y
K
C
Site 23
T303
E
E
C
G
K
A
F
T
Q
F
A
S
L
T
R
Site 24
S307
K
A
F
T
Q
F
A
S
L
T
R
H
K
R
I
Site 25
T316
T
R
H
K
R
I
H
T
G
E
K
P
Y
Q
C
Site 26
Y321
I
H
T
G
E
K
P
Y
Q
C
E
E
C
G
K
Site 27
S334
G
K
T
F
N
R
C
S
H
L
S
S
H
K
R
Site 28
S338
N
R
C
S
H
L
S
S
H
K
R
I
H
T
G
Site 29
T344
S
S
H
K
R
I
H
T
G
E
K
P
Y
K
C
Site 30
T357
K
C
E
E
C
G
R
T
F
T
Q
F
S
N
L
Site 31
T359
E
E
C
G
R
T
F
T
Q
F
S
N
L
T
Q
Site 32
Y377
I
H
T
G
E
K
P
Y
K
C
K
E
C
G
K
Site 33
S391
K
A
F
N
K
F
S
S
L
T
Q
H
R
R
I
Site 34
T393
F
N
K
F
S
S
L
T
Q
H
R
R
I
H
T
Site 35
T400
T
Q
H
R
R
I
H
T
G
V
K
P
Y
K
C
Site 36
S418
G
K
V
F
K
Q
C
S
H
L
T
S
H
K
R
Site 37
S422
K
Q
C
S
H
L
T
S
H
K
R
I
H
T
G
Site 38
T428
T
S
H
K
R
I
H
T
G
E
K
P
Y
K
C
Site 39
Y443
K
E
C
G
K
A
F
Y
Q
S
S
I
L
S
K
Site 40
S445
C
G
K
A
F
Y
Q
S
S
I
L
S
K
H
K
Site 41
S446
G
K
A
F
Y
Q
S
S
I
L
S
K
H
K
R
Site 42
S449
F
Y
Q
S
S
I
L
S
K
H
K
R
I
H
T
Site 43
T456
S
K
H
K
R
I
H
T
E
E
K
P
Y
K
C
Site 44
Y461
I
H
T
E
E
K
P
Y
K
C
E
E
C
G
K
Site 45
S474
G
K
A
F
N
Q
F
S
S
L
T
R
H
K
R
Site 46
S475
K
A
F
N
Q
F
S
S
L
T
R
H
K
R
I
Site 47
T484
T
R
H
K
R
I
H
T
G
E
K
R
Y
K
C
Site 48
Y489
I
H
T
G
E
K
R
Y
K
C
K
E
C
G
K
Site 49
Y499
K
E
C
G
K
G
F
Y
Q
S
S
I
H
S
K
Site 50
S502
G
K
G
F
Y
Q
S
S
I
H
S
K
Y
K
R
Site 51
Y507
Q
S
S
I
H
S
K
Y
K
R
I
Y
T
G
E
Site 52
Y511
H
S
K
Y
K
R
I
Y
T
G
E
E
P
D
K
Site 53
T512
S
K
Y
K
R
I
Y
T
G
E
E
P
D
K
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation