KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
C1orf125
Full Name:
Uncharacterized protein C1orf125
Alias:
CA125; chromosome 1 open reading frame 125; DKFZp686H1423; FLJ25438; FLJ32940; LOC126859
Type:
Mass (Da):
118030
Number AA:
UniProt ID:
Q5T1B0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
S
L
P
K
T
P
S
T
P
L
N
S
Site 2
S8
M
S
L
P
K
T
P
S
T
P
L
N
S
T
S
Site 3
T9
S
L
P
K
T
P
S
T
P
L
N
S
T
S
T
Site 4
S13
T
P
S
T
P
L
N
S
T
S
T
S
E
S
K
Site 5
S15
S
T
P
L
N
S
T
S
T
S
E
S
K
K
L
Site 6
S17
P
L
N
S
T
S
T
S
E
S
K
K
L
K
V
Site 7
S19
N
S
T
S
T
S
E
S
K
K
L
K
V
S
V
Site 8
S25
E
S
K
K
L
K
V
S
V
A
K
E
G
T
R
Site 9
S47
K
K
N
M
V
D
R
S
K
L
L
P
T
S
L
Site 10
S53
R
S
K
L
L
P
T
S
L
Q
N
E
F
I
P
Site 11
Y69
E
V
L
L
S
L
T
Y
A
A
N
A
G
P
C
Site 12
T88
L
P
P
K
K
I
K
T
P
K
G
T
L
P
R
Site 13
Y112
V
R
R
N
K
F
K
Y
L
I
D
H
P
V
S
Site 14
S119
Y
L
I
D
H
P
V
S
L
T
G
A
G
R
D
Site 15
S128
T
G
A
G
R
D
I
S
F
L
Y
D
V
T
Y
Site 16
Y131
G
R
D
I
S
F
L
Y
D
V
T
Y
A
K
G
Site 17
T134
I
S
F
L
Y
D
V
T
Y
A
K
G
Q
T
R
Site 18
Y135
S
F
L
Y
D
V
T
Y
A
K
G
Q
T
R
E
Site 19
S153
C
P
P
H
L
A
R
S
L
Q
S
H
D
G
V
Site 20
T168
I
V
P
H
K
P
K
T
L
T
D
T
L
I
P
Site 21
T170
P
H
K
P
K
T
L
T
D
T
L
I
P
E
E
Site 22
T172
K
P
K
T
L
T
D
T
L
I
P
E
E
F
H
Site 23
S183
E
E
F
H
I
V
S
S
T
G
V
S
G
L
E
Site 24
Y192
G
V
S
G
L
E
C
Y
D
D
K
Y
T
T
L
Site 25
Y196
L
E
C
Y
D
D
K
Y
T
T
L
L
T
D
S
Site 26
S212
N
R
L
L
L
F
P
S
M
K
P
N
K
R
V
Site 27
Y242
A
G
V
E
N
Q
E
Y
T
G
P
T
K
M
H
Site 28
Y262
L
K
K
E
Q
T
I
Y
N
M
I
F
H
E
L
Site 29
S274
H
E
L
I
R
Q
V
S
V
D
C
A
D
R
G
Site 30
S285
A
D
R
G
E
L
L
S
K
V
R
E
R
Y
V
Site 31
Y291
L
S
K
V
R
E
R
Y
V
Q
M
L
D
Q
I
Site 32
Y306
A
R
Q
M
I
D
F
Y
K
D
L
V
T
Q
R
Site 33
T311
D
F
Y
K
D
L
V
T
Q
R
V
M
D
Q
R
Site 34
Y379
V
E
E
Y
H
D
L
Y
T
L
Q
R
E
R
M
Site 35
T380
E
E
Y
H
D
L
Y
T
L
Q
R
E
R
M
E
Site 36
S402
A
E
R
D
I
W
S
S
A
T
Y
E
L
A
L
Site 37
Y424
V
I
L
A
R
R
L
Y
L
N
E
K
G
W
N
Site 38
Y433
N
E
K
G
W
N
K
Y
T
K
H
F
I
I
L
Site 39
S442
K
H
F
I
I
L
L
S
N
K
D
T
E
D
L
Site 40
S476
E
V
E
Q
M
E
E
S
T
S
E
T
L
K
I
Site 41
S478
E
Q
M
E
E
S
T
S
E
T
L
K
I
V
K
Site 42
T480
M
E
E
S
T
S
E
T
L
K
I
V
K
D
G
Site 43
S502
F
N
E
K
D
I
L
S
P
N
K
G
N
I
F
Site 44
Y539
G
D
V
L
L
S
K
Y
D
T
L
K
I
I
K
Site 45
S565
G
I
F
N
R
H
K
S
L
E
G
E
M
P
S
Site 46
S572
S
L
E
G
E
M
P
S
E
R
Q
Y
M
E
E
Site 47
Y576
E
M
P
S
E
R
Q
Y
M
E
E
I
I
K
N
Site 48
Y588
I
K
N
I
Q
K
L
Y
K
E
Y
E
I
R
I
Site 49
Y601
R
I
N
G
D
N
G
Y
S
K
I
L
P
S
L
Site 50
T627
E
N
L
E
F
P
D
T
P
L
E
E
W
Q
E
Site 51
S644
E
K
I
N
E
M
K
S
H
L
D
I
L
L
N
Site 52
S664
P
Q
H
I
D
V
D
S
V
S
V
L
Q
A
Y
Site 53
Y756
I
E
L
T
R
K
L
Y
Q
Y
S
S
Y
L
S
Site 54
Y758
L
T
R
K
L
Y
Q
Y
S
S
Y
L
S
S
C
Site 55
S759
T
R
K
L
Y
Q
Y
S
S
Y
L
S
S
C
C
Site 56
S760
R
K
L
Y
Q
Y
S
S
Y
L
S
S
C
C
K
Site 57
Y761
K
L
Y
Q
Y
S
S
Y
L
S
S
C
C
K
G
Site 58
T771
S
C
C
K
G
M
V
T
A
M
A
L
S
K
S
Site 59
S776
M
V
T
A
M
A
L
S
K
S
T
N
S
H
K
Site 60
S778
T
A
M
A
L
S
K
S
T
N
S
H
K
N
A
Site 61
Y790
K
N
A
T
E
D
L
Y
E
V
D
K
L
K
K
Site 62
Y800
D
K
L
K
K
E
C
Y
E
W
I
N
T
C
S
Site 63
S811
N
T
C
S
C
L
L
S
N
I
K
G
R
K
I
Site 64
T819
N
I
K
G
R
K
I
T
L
L
T
Y
E
E
I
Site 65
Y823
R
K
I
T
L
L
T
Y
E
E
I
E
R
L
L
Site 66
S846
I
E
P
E
I
D
E
S
F
K
E
D
E
E
E
Site 67
S873
E
R
A
E
E
Q
P
S
T
S
T
E
K
E
K
Site 68
T874
R
A
E
E
Q
P
S
T
S
T
E
K
E
K
L
Site 69
S893
G
E
D
E
N
V
H
S
K
P
L
F
E
T
D
Site 70
T899
H
S
K
P
L
F
E
T
D
V
L
S
S
W
R
Site 71
S903
L
F
E
T
D
V
L
S
S
W
R
E
S
A
K
Site 72
S904
F
E
T
D
V
L
S
S
W
R
E
S
A
K
Q
Site 73
S908
V
L
S
S
W
R
E
S
A
K
Q
G
T
L
A
Site 74
Y950
E
E
K
F
E
D
A
Y
E
K
L
H
H
T
L
Site 75
T969
D
L
E
E
L
V
M
T
S
R
K
E
S
K
E
Site 76
S974
V
M
T
S
R
K
E
S
K
E
E
K
E
N
Q
Site 77
S1000
Q
E
E
E
E
V
R
S
A
E
N
S
S
K
S
Site 78
S1004
E
V
R
S
A
E
N
S
S
K
S
P
K
K
G
Site 79
S1005
V
R
S
A
E
N
S
S
K
S
P
K
K
G
H
Site 80
S1007
S
A
E
N
S
S
K
S
P
K
K
G
H
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation