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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ARMC4
Full Name:
Armadillo repeat-containing protein 4
Alias:
Type:
Mass (Da):
115679
Number AA:
1044
UniProt ID:
Q5T2S8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
G
V
A
L
R
K
L
T
Q
W
T
A
A
G
H
Site 2
Y43
V
F
V
E
S
F
I
Y
K
H
P
Q
E
A
K
Site 3
S62
E
P
L
E
W
N
T
S
L
A
P
S
A
F
E
Site 4
S66
W
N
T
S
L
A
P
S
A
F
E
S
G
Y
V
Site 5
T77
S
G
Y
V
V
S
E
T
T
V
K
S
E
E
V
Site 6
S81
V
S
E
T
T
V
K
S
E
E
V
D
K
N
G
Site 7
S103
V
P
Q
I
K
I
R
S
F
G
Q
L
S
R
L
Site 8
S139
P
I
V
K
I
L
G
S
D
Y
N
T
M
K
E
Site 9
Y141
V
K
I
L
G
S
D
Y
N
T
M
K
E
N
S
Site 10
T143
I
L
G
S
D
Y
N
T
M
K
E
N
S
I
A
Site 11
S165
T
R
D
D
D
P
E
S
E
I
K
M
K
I
A
Site 12
S186
D
L
H
L
L
N
H
S
L
K
H
I
S
L
E
Site 13
S191
N
H
S
L
K
H
I
S
L
E
I
S
L
S
P
Site 14
T200
E
I
S
L
S
P
M
T
V
K
K
D
I
E
L
Site 15
S212
I
E
L
L
K
R
F
S
G
K
G
N
Q
T
V
Site 16
T218
F
S
G
K
G
N
Q
T
V
L
E
S
I
E
Y
Site 17
S222
G
N
Q
T
V
L
E
S
I
E
Y
T
S
D
Y
Site 18
Y225
T
V
L
E
S
I
E
Y
T
S
D
Y
E
F
S
Site 19
T226
V
L
E
S
I
E
Y
T
S
D
Y
E
F
S
N
Site 20
S227
L
E
S
I
E
Y
T
S
D
Y
E
F
S
N
G
Site 21
Y229
S
I
E
Y
T
S
D
Y
E
F
S
N
G
C
R
Site 22
Y249
Q
I
R
G
E
I
C
Y
V
L
V
K
P
H
D
Site 23
T259
V
K
P
H
D
G
E
T
L
C
I
T
C
S
A
Site 24
T276
V
F
L
N
G
G
K
T
D
D
E
G
D
V
N
Site 25
Y284
D
D
E
G
D
V
N
Y
E
R
K
G
S
I
Y
Site 26
S289
V
N
Y
E
R
K
G
S
I
Y
K
N
L
V
T
Site 27
Y291
Y
E
R
K
G
S
I
Y
K
N
L
V
T
F
L
Site 28
T296
S
I
Y
K
N
L
V
T
F
L
R
E
K
S
P
Site 29
S302
V
T
F
L
R
E
K
S
P
K
F
S
E
N
M
Site 30
S306
R
E
K
S
P
K
F
S
E
N
M
S
K
L
G
Site 31
S310
P
K
F
S
E
N
M
S
K
L
G
I
S
F
S
Site 32
S315
N
M
S
K
L
G
I
S
F
S
E
D
Q
Q
K
Site 33
S317
S
K
L
G
I
S
F
S
E
D
Q
Q
K
E
K
Site 34
S344
A
A
L
R
K
D
I
S
G
S
D
K
R
S
L
Site 35
S346
L
R
K
D
I
S
G
S
D
K
R
S
L
E
K
Site 36
S350
I
S
G
S
D
K
R
S
L
E
K
N
Q
I
N
Site 37
T376
P
S
L
N
W
K
T
T
V
N
Y
K
G
K
G
Site 38
Y379
N
W
K
T
T
V
N
Y
K
G
K
G
S
A
K
Site 39
T394
E
I
Q
E
D
K
H
T
G
K
L
E
K
P
R
Site 40
S403
K
L
E
K
P
R
P
S
V
S
H
G
R
A
Q
Site 41
S405
E
K
P
R
P
S
V
S
H
G
R
A
Q
L
L
Site 42
S415
R
A
Q
L
L
R
K
S
A
E
K
I
E
E
T
Site 43
T422
S
A
E
K
I
E
E
T
V
S
D
S
S
S
E
Site 44
S424
E
K
I
E
E
T
V
S
D
S
S
S
E
S
E
Site 45
S426
I
E
E
T
V
S
D
S
S
S
E
S
E
E
D
Site 46
S428
E
T
V
S
D
S
S
S
E
S
E
E
D
E
E
Site 47
S430
V
S
D
S
S
S
E
S
E
E
D
E
E
P
P
Site 48
S444
P
D
H
R
Q
E
A
S
A
D
L
P
S
E
Y
Site 49
Y451
S
A
D
L
P
S
E
Y
W
Q
I
Q
K
L
V
Site 50
Y460
Q
I
Q
K
L
V
K
Y
L
K
G
G
N
Q
T
Site 51
S480
L
C
S
M
R
D
F
S
L
A
Q
E
T
C
Q
Site 52
S522
L
K
I
L
K
E
I
S
H
N
P
Q
I
R
Q
Site 53
S550
I
L
D
S
P
H
K
S
L
K
C
L
A
A
E
Site 54
S591
L
L
D
C
A
H
D
S
T
K
P
A
Q
S
S
Site 55
Y600
K
P
A
Q
S
S
L
Y
E
A
R
D
V
E
V
Site 56
S621
A
L
W
S
C
S
K
S
H
T
N
K
E
A
I
Site 57
T623
W
S
C
S
K
S
H
T
N
K
E
A
I
R
K
Site 58
Y665
E
C
A
S
E
E
N
Y
R
A
A
I
K
A
E
Site 59
Y698
E
H
C
A
M
A
I
Y
Q
C
A
E
D
K
E
Site 60
T706
Q
C
A
E
D
K
E
T
R
D
L
V
R
L
H
Site 61
S721
G
G
L
K
P
L
A
S
L
L
N
N
T
D
N
Site 62
Y755
N
V
T
K
F
R
E
Y
K
A
I
E
T
L
V
Site 63
T760
R
E
Y
K
A
I
E
T
L
V
G
L
L
T
D
Site 64
S845
D
G
V
R
L
L
W
S
L
L
K
N
P
H
P
Site 65
S857
P
H
P
D
V
K
A
S
A
A
W
A
L
C
P
Site 66
S878
D
A
G
E
M
V
R
S
F
V
G
G
L
E
L
Site 67
S928
H
G
V
V
P
L
L
S
K
L
A
N
T
N
N
Site 68
S974
P
L
V
R
Y
L
K
S
N
D
T
N
V
H
R
Site 69
T983
D
T
N
V
H
R
A
T
A
Q
A
L
Y
Q
L
Site 70
Y988
R
A
T
A
Q
A
L
Y
Q
L
S
E
D
A
D
Site 71
S1015
L
L
L
D
M
V
G
S
P
D
Q
D
L
Q
E
Site 72
T1038
I
R
R
L
A
L
A
T
E
K
A
R
Y
T
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation