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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZFYVE27
Full Name:
Zinc finger FYVE domain-containing protein 27
Alias:
Type:
Mass (Da):
45843
Number AA:
411
UniProt ID:
Q5T4F4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
Q
T
S
E
R
E
G
S
G
P
E
L
S
P
S
Site 2
S14
E
G
S
G
P
E
L
S
P
S
V
M
P
E
A
Site 3
S16
S
G
P
E
L
S
P
S
V
M
P
E
A
P
L
Site 4
S25
M
P
E
A
P
L
E
S
P
P
F
P
T
K
S
Site 5
S32
S
P
P
F
P
T
K
S
P
A
F
D
L
F
N
Site 6
Y50
S
Y
K
R
L
E
I
Y
L
E
P
L
K
D
A
Site 7
Y63
D
A
G
D
G
V
R
Y
L
L
R
W
Q
M
P
Site 8
S120
C
R
A
R
L
P
D
S
E
L
M
R
R
K
Y
Site 9
Y127
S
E
L
M
R
R
K
Y
H
S
V
R
Q
E
D
Site 10
S129
L
M
R
R
K
Y
H
S
V
R
Q
E
D
L
Q
Site 11
S141
D
L
Q
R
G
R
L
S
R
P
E
A
V
A
E
Site 12
S224
V
E
F
F
R
V
V
S
E
Y
R
A
S
L
Q
Site 13
Y226
F
F
R
V
V
S
E
Y
R
A
S
L
Q
Q
R
Site 14
S229
V
V
S
E
Y
R
A
S
L
Q
Q
R
M
N
P
Site 15
S245
Q
E
E
H
A
F
E
S
P
P
P
P
D
V
G
Site 16
S260
G
K
D
G
L
M
D
S
T
P
A
L
T
P
T
Site 17
T261
K
D
G
L
M
D
S
T
P
A
L
T
P
T
E
Site 18
T265
M
D
S
T
P
A
L
T
P
T
E
D
L
T
P
Site 19
T267
S
T
P
A
L
T
P
T
E
D
L
T
P
G
S
Site 20
T271
L
T
P
T
E
D
L
T
P
G
S
V
E
E
A
Site 21
S274
T
E
D
L
T
P
G
S
V
E
E
A
E
E
A
Site 22
S322
L
Q
D
N
G
F
L
S
K
N
E
V
L
R
S
Site 23
S329
S
K
N
E
V
L
R
S
K
V
S
R
L
T
E
Site 24
T335
R
S
K
V
S
R
L
T
E
R
L
R
K
R
Y
Site 25
Y342
T
E
R
L
R
K
R
Y
P
T
N
N
F
G
N
Site 26
T344
R
L
R
K
R
Y
P
T
N
N
F
G
N
C
T
Site 27
T356
N
C
T
G
C
S
A
T
F
S
V
L
K
K
R
Site 28
S358
T
G
C
S
A
T
F
S
V
L
K
K
R
R
S
Site 29
S365
S
V
L
K
K
R
R
S
C
S
N
C
G
N
S
Site 30
S367
L
K
K
R
R
S
C
S
N
C
G
N
S
F
C
Site 31
S379
S
F
C
S
R
C
C
S
F
K
V
P
K
S
S
Site 32
S385
C
S
F
K
V
P
K
S
S
M
G
A
T
A
P
Site 33
S386
S
F
K
V
P
K
S
S
M
G
A
T
A
P
E
Site 34
T390
P
K
S
S
M
G
A
T
A
P
E
A
Q
R
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation