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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA1553
Full Name:
BEN domain-containing protein 3
Alias:
BEN domain containing 3; K1553; RP11-59I9.2
Type:
Mass (Da):
94475
Number AA:
828
UniProt ID:
Q5T5X7
International Prot ID:
IPI00741958
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
N
S
T
E
F
T
E
D
V
E
E
V
L
Site 2
S16
D
V
E
E
V
L
K
S
I
T
V
K
V
E
T
Site 3
T23
S
I
T
V
K
V
E
T
E
A
E
D
A
A
L
Site 4
S33
E
D
A
A
L
D
C
S
V
N
S
R
T
S
E
Site 5
S36
A
L
D
C
S
V
N
S
R
T
S
E
K
H
S
Site 6
S39
C
S
V
N
S
R
T
S
E
K
H
S
V
D
S
Site 7
S43
S
R
T
S
E
K
H
S
V
D
S
V
L
T
A
Site 8
S46
S
E
K
H
S
V
D
S
V
L
T
A
L
Q
D
Site 9
S54
V
L
T
A
L
Q
D
S
S
K
R
K
Q
L
V
Site 10
S55
L
T
A
L
Q
D
S
S
K
R
K
Q
L
V
S
Site 11
S62
S
K
R
K
Q
L
V
S
D
G
L
L
D
S
V
Site 12
S68
V
S
D
G
L
L
D
S
V
P
G
V
K
R
R
Site 13
S92
G
M
R
N
R
E
N
S
S
P
C
Q
G
N
G
Site 14
S93
M
R
N
R
E
N
S
S
P
C
Q
G
N
G
E
Site 15
S107
E
Q
A
G
R
G
R
S
L
G
N
V
W
P
G
Site 16
T123
E
E
P
C
N
D
A
T
T
P
S
Y
K
K
P
Site 17
T124
E
P
C
N
D
A
T
T
P
S
Y
K
K
P
L
Site 18
Y127
N
D
A
T
T
P
S
Y
K
K
P
L
Y
G
I
Site 19
Y132
P
S
Y
K
K
P
L
Y
G
I
S
H
K
I
M
Site 20
S146
M
E
K
K
N
P
P
S
G
D
L
L
N
V
Y
Site 21
Y153
S
G
D
L
L
N
V
Y
E
L
F
E
K
A
N
Site 22
S162
L
F
E
K
A
N
A
S
N
S
P
S
S
L
R
Site 23
S164
E
K
A
N
A
S
N
S
P
S
S
L
R
L
L
Site 24
S166
A
N
A
S
N
S
P
S
S
L
R
L
L
N
E
Site 25
S167
N
A
S
N
S
P
S
S
L
R
L
L
N
E
P
Site 26
S181
P
Q
K
R
D
C
G
S
T
G
A
G
T
D
N
Site 27
T182
Q
K
R
D
C
G
S
T
G
A
G
T
D
N
D
Site 28
Y193
T
D
N
D
P
N
I
Y
F
L
I
Q
K
M
F
Site 29
S208
Y
M
L
N
T
L
T
S
N
M
S
Q
L
H
S
Site 30
S211
N
T
L
T
S
N
M
S
Q
L
H
S
K
V
D
Site 31
S215
S
N
M
S
Q
L
H
S
K
V
D
L
L
S
L
Site 32
S221
H
S
K
V
D
L
L
S
L
E
V
S
R
I
K
Site 33
S225
D
L
L
S
L
E
V
S
R
I
K
K
Q
V
S
Site 34
S232
S
R
I
K
K
Q
V
S
P
T
E
M
V
A
K
Site 35
Y246
K
F
Q
P
P
P
E
Y
Q
L
T
A
A
E
L
Site 36
T249
P
P
P
E
Y
Q
L
T
A
A
E
L
K
Q
I
Site 37
S260
L
K
Q
I
V
D
Q
S
L
S
G
G
D
L
A
Site 38
S262
Q
I
V
D
Q
S
L
S
G
G
D
L
A
C
R
Site 39
S280
Q
L
F
P
E
L
F
S
D
V
D
F
S
R
G
Site 40
Y310
H
L
Q
L
I
R
N
Y
V
E
V
Y
Y
P
S
Site 41
Y315
R
N
Y
V
E
V
Y
Y
P
S
V
K
D
T
A
Site 42
T321
Y
Y
P
S
V
K
D
T
A
V
W
Q
A
E
C
Site 43
S348
A
Q
R
E
M
E
D
S
Q
P
S
G
Q
V
A
Site 44
S351
E
M
E
D
S
Q
P
S
G
Q
V
A
S
F
F
Site 45
S356
Q
P
S
G
Q
V
A
S
F
F
E
A
E
Q
V
Site 46
S379
K
D
Q
E
E
A
L
S
L
D
R
S
S
T
I
Site 47
S383
E
A
L
S
L
D
R
S
S
T
I
A
S
D
H
Site 48
S384
A
L
S
L
D
R
S
S
T
I
A
S
D
H
V
Site 49
T385
L
S
L
D
R
S
S
T
I
A
S
D
H
V
V
Site 50
S388
D
R
S
S
T
I
A
S
D
H
V
V
D
T
Q
Site 51
T394
A
S
D
H
V
V
D
T
Q
D
L
T
E
F
L
Site 52
T398
V
V
D
T
Q
D
L
T
E
F
L
D
E
A
S
Site 53
Y432
H
R
K
L
G
E
Q
Y
S
C
Y
G
D
G
G
Site 54
S433
R
K
L
G
E
Q
Y
S
C
Y
G
D
G
G
K
Site 55
Y435
L
G
E
Q
Y
S
C
Y
G
D
G
G
K
Q
E
Site 56
Y454
R
L
Q
I
I
R
N
Y
T
E
I
Y
F
P
D
Site 57
Y458
I
R
N
Y
T
E
I
Y
F
P
D
M
Q
E
E
Site 58
S489
G
L
G
L
D
A
G
S
E
G
D
P
P
R
D
Site 59
Y499
D
P
P
R
D
D
C
Y
D
S
S
S
L
P
D
Site 60
S501
P
R
D
D
C
Y
D
S
S
S
L
P
D
D
I
Site 61
S502
R
D
D
C
Y
D
S
S
S
L
P
D
D
I
S
Site 62
S503
D
D
C
Y
D
S
S
S
L
P
D
D
I
S
V
Site 63
S509
S
S
L
P
D
D
I
S
V
V
K
V
E
D
S
Site 64
S516
S
V
V
K
V
E
D
S
F
E
G
E
R
P
G
Site 65
S526
G
E
R
P
G
R
R
S
K
K
I
W
L
V
P
Site 66
S556
P
G
A
D
C
L
L
S
K
E
Q
L
R
S
I
Site 67
S562
L
S
K
E
Q
L
R
S
I
Y
E
S
S
L
S
Site 68
Y564
K
E
Q
L
R
S
I
Y
E
S
S
L
S
I
G
Site 69
S566
Q
L
R
S
I
Y
E
S
S
L
S
I
G
N
F
Site 70
S569
S
I
Y
E
S
S
L
S
I
G
N
F
A
S
R
Site 71
Y595
H
E
N
L
R
K
Q
Y
N
C
S
G
S
L
G
Site 72
S600
K
Q
Y
N
C
S
G
S
L
G
K
K
Q
L
D
Site 73
S609
G
K
K
Q
L
D
P
S
R
I
K
L
I
R
H
Site 74
Y617
R
I
K
L
I
R
H
Y
V
Q
L
L
Y
P
R
Site 75
Y622
R
H
Y
V
Q
L
L
Y
P
R
A
K
N
D
R
Site 76
T632
A
K
N
D
R
V
W
T
L
E
F
V
G
K
L
Site 77
T648
E
R
C
R
R
R
D
T
E
Q
R
R
S
Y
Q
Site 78
S653
R
D
T
E
Q
R
R
S
Y
Q
Q
Q
R
K
V
Site 79
Y654
D
T
E
Q
R
R
S
Y
Q
Q
Q
R
K
V
H
Site 80
T671
G
P
E
C
R
D
L
T
S
Y
A
I
N
P
E
Site 81
S672
P
E
C
R
D
L
T
S
Y
A
I
N
P
E
R
Site 82
Y673
E
C
R
D
L
T
S
Y
A
I
N
P
E
R
F
Site 83
S694
P
P
L
P
P
E
R
S
S
K
D
F
C
K
I
Site 84
S695
P
L
P
P
E
R
S
S
K
D
F
C
K
I
P
Site 85
S717
S
P
D
F
P
V
P
S
P
Y
L
L
S
D
K
Site 86
S722
V
P
S
P
Y
L
L
S
D
K
E
V
R
E
I
Site 87
Y761
A
E
N
L
R
L
Q
Y
N
H
S
G
A
C
N
Site 88
S764
L
R
L
Q
Y
N
H
S
G
A
C
N
K
K
Q
Site 89
T775
N
K
K
Q
L
D
P
T
R
L
R
L
I
R
H
Site 90
Y788
R
H
Y
V
E
A
V
Y
P
V
E
K
M
E
E
Site 91
Y799
K
M
E
E
V
W
H
Y
E
C
I
P
S
I
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation