KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZNF648
Full Name:
Zinc finger protein 648
Alias:
FLJ46813; Zn648; Znf648
Type:
Mass (Da):
62341
Number AA:
568
UniProt ID:
Q5T619
International Prot ID:
IPI00058344
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
Q
D
R
W
G
E
A
S
P
L
S
S
L
T
E
Site 2
S17
W
G
E
A
S
P
L
S
S
L
T
E
E
A
H
Site 3
S18
G
E
A
S
P
L
S
S
L
T
E
E
A
H
D
Site 4
T26
L
T
E
E
A
H
D
T
Q
M
L
S
M
N
L
Site 5
S30
A
H
D
T
Q
M
L
S
M
N
L
E
S
D
D
Site 6
T48
G
E
A
E
K
E
G
T
A
D
P
V
A
C
P
Site 7
S58
P
V
A
C
P
R
G
S
S
P
V
T
H
E
N
Site 8
S59
V
A
C
P
R
G
S
S
P
V
T
H
E
N
P
Site 9
T62
P
R
G
S
S
P
V
T
H
E
N
P
D
L
P
Site 10
S82
G
K
E
E
E
K
F
S
D
S
S
S
A
G
G
Site 11
S84
E
E
E
K
F
S
D
S
S
S
A
G
G
M
G
Site 12
S85
E
E
K
F
S
D
S
S
S
A
G
G
M
G
Q
Site 13
S86
E
K
F
S
D
S
S
S
A
G
G
M
G
Q
K
Site 14
S98
G
Q
K
P
V
E
M
S
G
K
A
S
W
S
R
Site 15
S102
V
E
M
S
G
K
A
S
W
S
R
D
V
T
K
Site 16
S104
M
S
G
K
A
S
W
S
R
D
V
T
K
I
N
Site 17
T108
A
S
W
S
R
D
V
T
K
I
N
E
T
Q
G
Site 18
S116
K
I
N
E
T
Q
G
S
P
G
A
S
R
A
L
Site 19
S120
T
Q
G
S
P
G
A
S
R
A
L
G
S
L
P
Site 20
Y152
L
P
A
G
D
D
G
Y
S
G
A
N
Q
D
A
Site 21
S153
P
A
G
D
D
G
Y
S
G
A
N
Q
D
A
V
Site 22
S166
A
V
L
D
V
P
P
S
F
P
S
N
G
K
Y
Site 23
S169
D
V
P
P
S
F
P
S
N
G
K
Y
L
C
A
Site 24
Y173
S
F
P
S
N
G
K
Y
L
C
A
H
K
S
V
Site 25
S179
K
Y
L
C
A
H
K
S
V
D
T
S
A
G
N
Site 26
S183
A
H
K
S
V
D
T
S
A
G
N
S
S
L
L
Site 27
S187
V
D
T
S
A
G
N
S
S
L
L
C
F
P
R
Site 28
S188
D
T
S
A
G
N
S
S
L
L
C
F
P
R
P
Site 29
S197
L
C
F
P
R
P
G
S
N
W
D
L
P
T
Q
Site 30
T203
G
S
N
W
D
L
P
T
Q
E
T
H
T
P
A
Site 31
T208
L
P
T
Q
E
T
H
T
P
A
Q
A
S
A
T
Site 32
S230
V
L
A
K
A
R
N
S
R
K
V
Q
N
Q
A
Site 33
Y250
G
E
A
E
A
R
P
Y
R
C
L
R
G
G
R
Site 34
S263
G
R
A
F
Q
K
P
S
K
P
L
S
P
A
E
Site 35
S267
Q
K
P
S
K
P
L
S
P
A
E
T
R
G
G
Site 36
Y279
R
G
G
A
A
K
R
Y
A
C
E
L
C
G
K
Site 37
Y288
C
E
L
C
G
K
A
Y
S
H
R
G
T
L
Q
Site 38
S289
E
L
C
G
K
A
Y
S
H
R
G
T
L
Q
Q
Site 39
T293
K
A
Y
S
H
R
G
T
L
Q
Q
H
R
R
L
Site 40
T302
Q
Q
H
R
R
L
H
T
G
E
R
P
Y
Q
C
Site 41
Y307
L
H
T
G
E
R
P
Y
Q
C
S
F
C
D
K
Site 42
T328
D
H
R
K
H
I
R
T
H
T
G
E
K
P
Y
Site 43
T330
R
K
H
I
R
T
H
T
G
E
K
P
Y
P
C
Site 44
Y335
T
H
T
G
E
K
P
Y
P
C
P
D
C
G
K
Site 45
S347
C
G
K
A
F
V
R
S
S
D
L
R
K
H
Q
Site 46
S348
G
K
A
F
V
R
S
S
D
L
R
K
H
Q
R
Site 47
S359
K
H
Q
R
N
M
H
S
N
N
K
P
F
P
C
Site 48
S367
N
N
K
P
F
P
C
S
E
C
G
L
T
F
N
Site 49
T372
P
C
S
E
C
G
L
T
F
N
K
P
L
S
L
Site 50
S378
L
T
F
N
K
P
L
S
L
L
R
H
Q
R
T
Site 51
S415
V
E
H
Q
R
V
H
S
G
E
R
P
F
P
C
Site 52
T430
P
T
C
G
K
C
F
T
K
S
S
N
L
S
E
Site 53
S432
C
G
K
C
F
T
K
S
S
N
L
S
E
H
Q
Site 54
S433
G
K
C
F
T
K
S
S
N
L
S
E
H
Q
T
Site 55
S436
F
T
K
S
S
N
L
S
E
H
Q
T
L
H
T
Site 56
T440
S
N
L
S
E
H
Q
T
L
H
T
G
Q
R
P
Site 57
S461
G
V
A
F
A
Q
P
S
R
L
V
R
H
Q
R
Site 58
T471
V
R
H
Q
R
I
H
T
G
E
R
P
F
P
C
Site 59
T479
G
E
R
P
F
P
C
T
Q
C
G
Q
A
F
A
Site 60
S488
C
G
Q
A
F
A
R
S
S
T
L
K
R
H
Q
Site 61
S489
G
Q
A
F
A
R
S
S
T
L
K
R
H
Q
Q
Site 62
T490
Q
A
F
A
R
S
S
T
L
K
R
H
Q
Q
I
Site 63
S517
G
R
A
F
R
I
A
S
E
L
A
Q
H
I
R
Site 64
Y532
M
H
N
G
E
R
P
Y
Q
C
E
D
C
G
Q
Site 65
T556
R
H
R
A
K
H
G
T
C
K
K
E
P
I
P
Site 66
S564
C
K
K
E
P
I
P
S
S
S
D
E
_
_
_
Site 67
S565
K
K
E
P
I
P
S
S
S
D
E
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation