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Updated November 2019
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Protein Info
Short Name:
KIF24
Full Name:
Kinesin-like protein KIF24
Alias:
bA571F15.4; C9orf48; FLJ10933; FLJ43884; kinesin family member 24; kinesin-like KIF24
Type:
Motor protein; Microtubule binding protein
Mass (Da):
151900
Number AA:
UniProt ID:
Q5T7B8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005874
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0003777
PhosphoSite+
KinaseNET
Biological Process:
GO:0007018
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y17
C
E
A
E
L
A
Q
Y
Y
S
H
F
T
A
L
Site 2
Y40
A
K
I
T
M
K
D
Y
S
K
L
G
V
H
D
Site 3
S81
P
E
R
H
L
Q
T
S
S
L
R
I
K
S
Q
Site 4
S82
E
R
H
L
Q
T
S
S
L
R
I
K
S
Q
E
Site 5
S87
T
S
S
L
R
I
K
S
Q
E
L
R
S
G
P
Site 6
S92
I
K
S
Q
E
L
R
S
G
P
R
R
Q
L
N
Site 7
S102
R
R
Q
L
N
F
D
S
P
A
D
N
K
D
R
Site 8
S112
D
N
K
D
R
N
A
S
N
D
G
F
E
M
C
Site 9
S120
N
D
G
F
E
M
C
S
L
S
D
F
S
A
N
Site 10
S122
G
F
E
M
C
S
L
S
D
F
S
A
N
E
Q
Site 11
T132
S
A
N
E
Q
K
S
T
Y
L
K
V
L
E
H
Site 12
Y133
A
N
E
Q
K
S
T
Y
L
K
V
L
E
H
M
Site 13
S145
E
H
M
L
P
D
D
S
Q
Y
H
T
K
T
G
Site 14
Y147
M
L
P
D
D
S
Q
Y
H
T
K
T
G
I
L
Site 15
T149
P
D
D
S
Q
Y
H
T
K
T
G
I
L
N
A
Site 16
Y162
N
A
T
A
G
D
S
Y
V
Q
T
E
I
S
T
Site 17
T165
A
G
D
S
Y
V
Q
T
E
I
S
T
S
L
F
Site 18
S168
S
Y
V
Q
T
E
I
S
T
S
L
F
S
P
N
Site 19
S170
V
Q
T
E
I
S
T
S
L
F
S
P
N
Y
L
Site 20
Y198
R
I
S
H
V
S
G
Y
N
Y
G
I
P
H
S
Site 21
Y200
S
H
V
S
G
Y
N
Y
G
I
P
H
S
C
I
Site 22
T211
H
S
C
I
R
Q
N
T
S
E
K
Q
N
P
W
Site 23
T219
S
E
K
Q
N
P
W
T
E
M
E
K
I
R
V
Site 24
T247
R
G
E
I
N
I
I
T
V
E
D
K
E
T
L
Site 25
T253
I
T
V
E
D
K
E
T
L
L
V
H
E
K
K
Site 26
T266
K
K
E
A
V
D
L
T
Q
Y
I
L
Q
H
V
Site 27
Y290
A
C
T
N
Q
D
V
Y
M
K
T
T
H
P
L
Site 28
Y312
G
N
A
T
C
F
A
Y
G
Q
T
G
A
G
K
Site 29
Y321
Q
T
G
A
G
K
T
Y
T
M
I
G
T
H
E
Site 30
T322
T
G
A
G
K
T
Y
T
M
I
G
T
H
E
N
Site 31
S347
I
F
R
Q
L
E
V
S
Q
P
R
K
H
L
F
Site 32
Y368
E
I
Y
C
G
Q
L
Y
D
L
L
N
R
R
K
Site 33
S383
R
L
F
A
R
E
D
S
K
H
M
V
Q
I
V
Site 34
S411
L
E
V
I
L
K
G
S
K
E
R
S
T
G
A
Site 35
S415
L
K
G
S
K
E
R
S
T
G
A
T
G
V
N
Site 36
T416
K
G
S
K
E
R
S
T
G
A
T
G
V
N
A
Site 37
T419
K
E
R
S
T
G
A
T
G
V
N
A
D
S
S
Site 38
S425
A
T
G
V
N
A
D
S
S
R
S
H
A
V
I
Site 39
S426
T
G
V
N
A
D
S
S
R
S
H
A
V
I
Q
Site 40
T443
I
K
D
S
A
K
R
T
F
G
R
I
S
F
I
Site 41
S448
K
R
T
F
G
R
I
S
F
I
D
L
A
G
S
Site 42
S455
S
F
I
D
L
A
G
S
E
R
A
A
D
A
R
Site 43
S464
R
A
A
D
A
R
D
S
D
R
Q
T
K
M
E
Site 44
T468
A
R
D
S
D
R
Q
T
K
M
E
G
A
E
I
Site 45
S478
E
G
A
E
I
N
Q
S
L
L
A
L
K
E
C
Site 46
T494
R
A
L
D
Q
E
H
T
H
T
P
F
R
Q
S
Site 47
T496
L
D
Q
E
H
T
H
T
P
F
R
Q
S
K
L
Site 48
S501
T
H
T
P
F
R
Q
S
K
L
T
Q
V
L
K
Site 49
T504
P
F
R
Q
S
K
L
T
Q
V
L
K
D
S
F
Site 50
S510
L
T
Q
V
L
K
D
S
F
I
G
N
A
K
T
Site 51
T530
I
S
P
S
H
V
A
T
E
H
T
L
N
T
L
Site 52
T536
A
T
E
H
T
L
N
T
L
R
Y
A
D
R
V
Site 53
Y539
H
T
L
N
T
L
R
Y
A
D
R
V
K
E
L
Site 54
T554
K
K
G
I
K
C
C
T
S
V
T
S
R
N
R
Site 55
S555
K
G
I
K
C
C
T
S
V
T
S
R
N
R
T
Site 56
T557
I
K
C
C
T
S
V
T
S
R
N
R
T
S
G
Site 57
S558
K
C
C
T
S
V
T
S
R
N
R
T
S
G
N
Site 58
T562
S
V
T
S
R
N
R
T
S
G
N
S
S
P
K
Site 59
S563
V
T
S
R
N
R
T
S
G
N
S
S
P
K
R
Site 60
S566
R
N
R
T
S
G
N
S
S
P
K
R
I
Q
S
Site 61
S567
N
R
T
S
G
N
S
S
P
K
R
I
Q
S
S
Site 62
S573
S
S
P
K
R
I
Q
S
S
P
G
A
L
S
E
Site 63
S574
S
P
K
R
I
Q
S
S
P
G
A
L
S
E
D
Site 64
S579
Q
S
S
P
G
A
L
S
E
D
K
C
S
P
K
Site 65
S584
A
L
S
E
D
K
C
S
P
K
K
V
K
L
G
Site 66
S603
L
T
V
A
A
P
G
S
T
R
G
K
V
H
P
Site 67
T612
R
G
K
V
H
P
L
T
S
H
P
P
N
I
P
Site 68
S613
G
K
V
H
P
L
T
S
H
P
P
N
I
P
F
Site 69
T621
H
P
P
N
I
P
F
T
S
A
P
K
V
S
G
Site 70
S622
P
P
N
I
P
F
T
S
A
P
K
V
S
G
K
Site 71
S627
F
T
S
A
P
K
V
S
G
K
R
G
G
S
R
Site 72
S633
V
S
G
K
R
G
G
S
R
G
S
P
S
Q
E
Site 73
S636
K
R
G
G
S
R
G
S
P
S
Q
E
W
V
I
Site 74
S638
G
G
S
R
G
S
P
S
Q
E
W
V
I
H
A
Site 75
S646
Q
E
W
V
I
H
A
S
P
V
K
G
T
V
R
Site 76
S665
A
K
K
K
P
E
E
S
A
P
L
C
S
E
K
Site 77
T679
K
N
R
M
G
N
K
T
V
L
G
W
E
S
R
Site 78
S688
L
G
W
E
S
R
A
S
G
P
G
E
G
L
V
Site 79
T701
L
V
R
G
K
L
S
T
K
C
K
K
V
Q
T
Site 80
T708
T
K
C
K
K
V
Q
T
V
Q
P
V
Q
K
Q
Site 81
S718
P
V
Q
K
Q
L
V
S
R
V
E
L
S
F
G
Site 82
S723
L
V
S
R
V
E
L
S
F
G
N
A
H
H
R
Site 83
Y733
N
A
H
H
R
A
E
Y
S
Q
D
S
Q
R
G
Site 84
S734
A
H
H
R
A
E
Y
S
Q
D
S
Q
R
G
T
Site 85
S737
R
A
E
Y
S
Q
D
S
Q
R
G
T
P
A
R
Site 86
T741
S
Q
D
S
Q
R
G
T
P
A
R
P
A
S
E
Site 87
S747
G
T
P
A
R
P
A
S
E
A
W
T
N
I
P
Site 88
T751
R
P
A
S
E
A
W
T
N
I
P
P
H
Q
K
Site 89
Y767
R
E
E
H
L
R
F
Y
H
Q
Q
F
Q
Q
P
Site 90
Y783
L
L
Q
Q
K
L
K
Y
Q
P
L
K
R
S
L
Site 91
S789
K
Y
Q
P
L
K
R
S
L
R
Q
Y
R
P
P
Site 92
Y793
L
K
R
S
L
R
Q
Y
R
P
P
E
G
Q
L
Site 93
T801
R
P
P
E
G
Q
L
T
N
E
T
P
P
L
F
Site 94
T804
E
G
Q
L
T
N
E
T
P
P
L
F
H
S
Y
Site 95
S810
E
T
P
P
L
F
H
S
Y
S
E
N
H
D
G
Site 96
S812
P
P
L
F
H
S
Y
S
E
N
H
D
G
A
Q
Site 97
S826
Q
V
E
E
L
D
D
S
D
F
S
E
D
S
F
Site 98
S829
E
L
D
D
S
D
F
S
E
D
S
F
S
H
I
Site 99
S832
D
S
D
F
S
E
D
S
F
S
H
I
S
S
Q
Site 100
S834
D
F
S
E
D
S
F
S
H
I
S
S
Q
R
A
Site 101
S838
D
S
F
S
H
I
S
S
Q
R
A
T
K
Q
R
Site 102
T842
H
I
S
S
Q
R
A
T
K
Q
R
N
T
L
E
Site 103
T847
R
A
T
K
Q
R
N
T
L
E
N
S
E
D
S
Site 104
S851
Q
R
N
T
L
E
N
S
E
D
S
F
F
L
H
Site 105
S854
T
L
E
N
S
E
D
S
F
F
L
H
Q
T
W
Site 106
T860
D
S
F
F
L
H
Q
T
W
G
Q
G
P
E
K
Site 107
S875
Q
V
A
E
R
Q
Q
S
L
F
S
S
P
R
T
Site 108
S878
E
R
Q
Q
S
L
F
S
S
P
R
T
G
D
K
Site 109
S879
R
Q
Q
S
L
F
S
S
P
R
T
G
D
K
K
Site 110
T882
S
L
F
S
S
P
R
T
G
D
K
K
D
L
T
Site 111
T889
T
G
D
K
K
D
L
T
K
S
W
V
D
S
R
Site 112
S891
D
K
K
D
L
T
K
S
W
V
D
S
R
D
P
Site 113
S895
L
T
K
S
W
V
D
S
R
D
P
I
N
H
R
Site 114
S909
R
R
A
A
L
D
H
S
C
S
P
S
K
G
P
Site 115
S911
A
A
L
D
H
S
C
S
P
S
K
G
P
V
D
Site 116
S913
L
D
H
S
C
S
P
S
K
G
P
V
D
W
S
Site 117
S920
S
K
G
P
V
D
W
S
R
E
N
S
T
S
S
Site 118
S924
V
D
W
S
R
E
N
S
T
S
S
G
P
S
P
Site 119
S926
W
S
R
E
N
S
T
S
S
G
P
S
P
R
D
Site 120
S927
S
R
E
N
S
T
S
S
G
P
S
P
R
D
S
Site 121
S930
N
S
T
S
S
G
P
S
P
R
D
S
L
A
E
Site 122
S934
S
G
P
S
P
R
D
S
L
A
E
K
P
Y
C
Site 123
Y940
D
S
L
A
E
K
P
Y
C
S
Q
V
D
F
I
Site 124
S942
L
A
E
K
P
Y
C
S
Q
V
D
F
I
Y
R
Site 125
Y948
C
S
Q
V
D
F
I
Y
R
Q
E
R
G
G
G
Site 126
S956
R
Q
E
R
G
G
G
S
S
F
D
L
R
K
D
Site 127
S957
Q
E
R
G
G
G
S
S
F
D
L
R
K
D
A
Site 128
S965
F
D
L
R
K
D
A
S
Q
S
E
V
S
G
E
Site 129
S967
L
R
K
D
A
S
Q
S
E
V
S
G
E
N
E
Site 130
S979
E
N
E
G
N
L
P
S
P
E
E
D
G
F
T
Site 131
T986
S
P
E
E
D
G
F
T
I
S
L
S
H
V
A
Site 132
S997
S
H
V
A
V
P
G
S
P
D
Q
R
D
T
V
Site 133
T1003
G
S
P
D
Q
R
D
T
V
T
T
P
L
R
E
Site 134
T1005
P
D
Q
R
D
T
V
T
T
P
L
R
E
V
S
Site 135
T1006
D
Q
R
D
T
V
T
T
P
L
R
E
V
S
A
Site 136
S1012
T
T
P
L
R
E
V
S
A
D
G
P
I
Q
V
Site 137
S1021
D
G
P
I
Q
V
T
S
T
V
K
N
G
H
A
Site 138
T1022
G
P
I
Q
V
T
S
T
V
K
N
G
H
A
V
Site 139
T1040
D
P
R
G
Q
L
G
T
H
A
E
Y
A
S
G
Site 140
Y1044
Q
L
G
T
H
A
E
Y
A
S
G
L
M
S
P
Site 141
S1046
G
T
H
A
E
Y
A
S
G
L
M
S
P
L
T
Site 142
S1055
L
M
S
P
L
T
M
S
L
L
E
N
P
D
N
Site 143
S1065
E
N
P
D
N
E
G
S
P
P
S
E
Q
L
V
Site 144
S1068
D
N
E
G
S
P
P
S
E
Q
L
V
Q
D
G
Site 145
S1079
V
Q
D
G
A
T
H
S
L
V
A
E
S
T
G
Site 146
T1085
H
S
L
V
A
E
S
T
G
G
P
V
V
S
H
Site 147
S1091
S
T
G
G
P
V
V
S
H
T
V
P
S
G
D
Site 148
T1093
G
G
P
V
V
S
H
T
V
P
S
G
D
Q
E
Site 149
S1106
Q
E
A
A
L
P
V
S
S
A
T
R
H
L
W
Site 150
S1115
A
T
R
H
L
W
L
S
S
S
P
P
D
N
K
Site 151
S1116
T
R
H
L
W
L
S
S
S
P
P
D
N
K
P
Site 152
S1117
R
H
L
W
L
S
S
S
P
P
D
N
K
P
G
Site 153
S1131
G
G
D
L
P
A
L
S
P
S
P
I
R
Q
H
Site 154
S1133
D
L
P
A
L
S
P
S
P
I
R
Q
H
P
A
Site 155
S1156
D
L
G
E
A
C
Q
S
R
E
T
V
L
F
S
Site 156
T1159
E
A
C
Q
S
R
E
T
V
L
F
S
H
E
H
Site 157
S1184
E
E
T
G
L
D
G
S
W
G
F
P
G
K
P
Site 158
S1202
I
H
M
G
V
P
H
S
G
P
T
L
T
P
R
Site 159
T1205
G
V
P
H
S
G
P
T
L
T
P
R
T
G
S
Site 160
T1207
P
H
S
G
P
T
L
T
P
R
T
G
S
S
D
Site 161
T1210
G
P
T
L
T
P
R
T
G
S
S
D
V
A
D
Site 162
S1212
T
L
T
P
R
T
G
S
S
D
V
A
D
Q
L
Site 163
S1213
L
T
P
R
T
G
S
S
D
V
A
D
Q
L
W
Site 164
S1238
G
W
Q
E
F
G
L
S
T
D
P
I
K
L
P
Site 165
T1252
P
C
N
S
E
N
V
T
W
L
K
P
R
P
I
Site 166
S1260
W
L
K
P
R
P
I
S
R
C
L
A
R
P
S
Site 167
S1267
S
R
C
L
A
R
P
S
S
P
L
V
P
S
C
Site 168
S1268
R
C
L
A
R
P
S
S
P
L
V
P
S
C
S
Site 169
S1273
P
S
S
P
L
V
P
S
C
S
P
K
T
A
G
Site 170
S1275
S
P
L
V
P
S
C
S
P
K
T
A
G
T
L
Site 171
T1281
C
S
P
K
T
A
G
T
L
R
Q
P
T
L
E
Site 172
T1286
A
G
T
L
R
Q
P
T
L
E
Q
A
Q
Q
V
Site 173
T1314
E
L
G
F
K
E
E
T
L
M
S
Q
L
A
S
Site 174
S1317
F
K
E
E
T
L
M
S
Q
L
A
S
N
D
F
Site 175
S1321
T
L
M
S
Q
L
A
S
N
D
F
E
D
F
V
Site 176
T1329
N
D
F
E
D
F
V
T
Q
L
D
E
I
M
V
Site 177
S1339
D
E
I
M
V
L
K
S
K
C
I
Q
S
L
R
Site 178
S1344
L
K
S
K
C
I
Q
S
L
R
S
Q
L
Q
L
Site 179
S1347
K
C
I
Q
S
L
R
S
Q
L
Q
L
Y
L
T
Site 180
Y1352
L
R
S
Q
L
Q
L
Y
L
T
C
H
G
P
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation