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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
L1TD1
Full Name:
LINE-1 type transposase domain-containing protein 1
Alias:
ECAT11; ES cell- associated 11
Type:
Mass (Da):
98850
Number AA:
865
UniProt ID:
Q5T7N2
International Prot ID:
IPI00253050
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
D
V
S
T
S
V
Q
Site 2
T6
_
_
M
S
D
V
S
T
S
V
Q
S
K
F
A
Site 3
S7
_
M
S
D
V
S
T
S
V
Q
S
K
F
A
R
Site 4
Y24
K
K
K
E
N
I
T
Y
M
K
R
E
Q
L
T
Site 5
S49
D
L
K
C
K
D
V
S
A
I
M
N
K
F
K
Site 6
T72
M
F
E
E
M
R
E
T
L
K
N
D
L
K
A
Site 7
S93
T
I
P
E
V
K
N
S
E
N
S
S
S
R
T
Site 8
S97
V
K
N
S
E
N
S
S
S
R
T
E
F
Q
Q
Site 9
S98
K
N
S
E
N
S
S
S
R
T
E
F
Q
Q
I
Site 10
T100
S
E
N
S
S
S
R
T
E
F
Q
Q
I
I
N
Site 11
S124
G
K
I
E
G
E
N
S
K
I
G
D
D
N
E
Site 12
T134
G
D
D
N
E
N
L
T
F
K
L
E
V
N
E
Site 13
S143
K
L
E
V
N
E
L
S
G
K
L
D
N
T
N
Site 14
T149
L
S
G
K
L
D
N
T
N
E
Y
N
S
N
D
Site 15
Y152
K
L
D
N
T
N
E
Y
N
S
N
D
G
K
K
Site 16
S154
D
N
T
N
E
Y
N
S
N
D
G
K
K
L
P
Site 17
S165
K
K
L
P
Q
G
E
S
R
S
Y
E
V
M
G
Site 18
S167
L
P
Q
G
E
S
R
S
Y
E
V
M
G
S
M
Site 19
Y168
P
Q
G
E
S
R
S
Y
E
V
M
G
S
M
E
Site 20
S173
R
S
Y
E
V
M
G
S
M
E
E
T
L
C
N
Site 21
T177
V
M
G
S
M
E
E
T
L
C
N
I
D
D
R
Site 22
T195
R
N
V
H
L
E
F
T
E
R
E
S
R
K
D
Site 23
S199
L
E
F
T
E
R
E
S
R
K
D
G
E
D
E
Site 24
T253
V
A
D
L
S
S
A
T
L
D
I
S
K
Q
W
Site 25
S257
S
S
A
T
L
D
I
S
K
Q
W
S
N
V
F
Site 26
T292
K
C
D
G
E
I
K
T
F
S
D
L
Q
S
L
Site 27
S294
D
G
E
I
K
T
F
S
D
L
Q
S
L
R
K
Site 28
S298
K
T
F
S
D
L
Q
S
L
R
K
F
A
S
Q
Site 29
S304
Q
S
L
R
K
F
A
S
Q
K
S
S
V
K
E
Site 30
S307
R
K
F
A
S
Q
K
S
S
V
K
E
L
L
K
Site 31
S308
K
F
A
S
Q
K
S
S
V
K
E
L
L
K
D
Site 32
Y330
I
N
Q
G
G
R
K
Y
G
I
Q
E
K
R
D
Site 33
T339
I
Q
E
K
R
D
K
T
L
I
D
S
K
H
R
Site 34
S343
R
D
K
T
L
I
D
S
K
H
R
A
G
E
I
Site 35
T351
K
H
R
A
G
E
I
T
S
D
G
L
S
F
L
Site 36
S352
H
R
A
G
E
I
T
S
D
G
L
S
F
L
F
Site 37
S382
E
T
Q
E
E
E
F
S
E
L
E
E
L
D
E
Site 38
T400
G
M
E
D
D
E
D
T
S
G
L
E
E
E
E
Site 39
S411
E
E
E
E
E
E
P
S
G
L
E
E
E
E
E
Site 40
S422
E
E
E
E
E
E
A
S
G
L
E
E
D
E
A
Site 41
S430
G
L
E
E
D
E
A
S
G
L
E
E
E
E
E
Site 42
T439
L
E
E
E
E
E
Q
T
S
E
Q
D
S
T
F
Site 43
S440
E
E
E
E
E
Q
T
S
E
Q
D
S
T
F
Q
Site 44
S444
E
Q
T
S
E
Q
D
S
T
F
Q
G
H
T
L
Site 45
T445
Q
T
S
E
Q
D
S
T
F
Q
G
H
T
L
V
Site 46
T450
D
S
T
F
Q
G
H
T
L
V
D
A
K
H
E
Site 47
T461
A
K
H
E
V
E
I
T
S
D
G
M
E
T
T
Site 48
S462
K
H
E
V
E
I
T
S
D
G
M
E
T
T
F
Site 49
T468
T
S
D
G
M
E
T
T
F
I
D
S
V
E
D
Site 50
S472
M
E
T
T
F
I
D
S
V
E
D
S
E
S
E
Site 51
S476
F
I
D
S
V
E
D
S
E
S
E
E
E
E
E
Site 52
S478
D
S
V
E
D
S
E
S
E
E
E
E
E
G
K
Site 53
S486
E
E
E
E
E
G
K
S
S
E
T
G
K
V
K
Site 54
S487
E
E
E
E
G
K
S
S
E
T
G
K
V
K
T
Site 55
S496
T
G
K
V
K
T
T
S
L
T
E
K
K
A
S
Site 56
T498
K
V
K
T
T
S
L
T
E
K
K
A
S
R
R
Site 57
S503
S
L
T
E
K
K
A
S
R
R
Q
K
E
I
P
Site 58
S512
R
Q
K
E
I
P
F
S
Y
L
V
G
D
S
G
Site 59
Y513
Q
K
E
I
P
F
S
Y
L
V
G
D
S
G
K
Site 60
S518
F
S
Y
L
V
G
D
S
G
K
K
K
L
V
K
Site 61
T538
K
T
Q
E
E
E
E
T
A
V
P
T
S
Q
G
Site 62
S543
E
E
T
A
V
P
T
S
Q
G
T
G
T
P
C
Site 63
T546
A
V
P
T
S
Q
G
T
G
T
P
C
L
T
L
Site 64
T548
P
T
S
Q
G
T
G
T
P
C
L
T
L
C
L
Site 65
T552
G
T
G
T
P
C
L
T
L
C
L
A
S
P
S
Site 66
S557
C
L
T
L
C
L
A
S
P
S
K
S
L
E
M
Site 67
S559
T
L
C
L
A
S
P
S
K
S
L
E
M
S
H
Site 68
S561
C
L
A
S
P
S
K
S
L
E
M
S
H
D
E
Site 69
S565
P
S
K
S
L
E
M
S
H
D
E
H
K
K
H
Site 70
S573
H
D
E
H
K
K
H
S
H
T
N
L
S
I
S
Site 71
S578
K
H
S
H
T
N
L
S
I
S
T
G
V
T
K
Site 72
T584
L
S
I
S
T
G
V
T
K
L
K
K
T
E
E
Site 73
T599
K
K
H
R
T
L
H
T
E
E
L
T
S
K
E
Site 74
S604
L
H
T
E
E
L
T
S
K
E
A
D
L
T
E
Site 75
T610
T
S
K
E
A
D
L
T
E
E
T
E
E
N
L
Site 76
S619
E
T
E
E
N
L
R
S
S
V
I
N
S
I
R
Site 77
S620
T
E
E
N
L
R
S
S
V
I
N
S
I
R
E
Site 78
S624
L
R
S
S
V
I
N
S
I
R
E
I
K
E
E
Site 79
S637
E
E
I
G
N
L
K
S
S
H
S
G
V
L
E
Site 80
S638
E
I
G
N
L
K
S
S
H
S
G
V
L
E
I
Site 81
S640
G
N
L
K
S
S
H
S
G
V
L
E
I
E
N
Site 82
S648
G
V
L
E
I
E
N
S
V
D
D
L
S
S
R
Site 83
S653
E
N
S
V
D
D
L
S
S
R
M
D
I
L
E
Site 84
S654
N
S
V
D
D
L
S
S
R
M
D
I
L
E
E
Site 85
S665
I
L
E
E
R
I
D
S
L
E
D
Q
I
E
E
Site 86
S686
Q
M
T
K
Q
I
I
S
K
E
R
Q
R
D
I
Site 87
S699
D
I
E
E
R
S
R
S
C
N
I
R
L
I
G
Site 88
Y713
G
I
P
E
K
E
S
Y
E
N
R
A
E
D
I
Site 89
S736
F
A
E
L
K
K
G
S
S
L
E
I
V
S
A
Site 90
S737
A
E
L
K
K
G
S
S
L
E
I
V
S
A
C
Site 91
S742
G
S
S
L
E
I
V
S
A
C
R
V
P
S
K
Site 92
S748
V
S
A
C
R
V
P
S
K
I
D
E
K
R
L
Site 93
T756
K
I
D
E
K
R
L
T
P
R
H
I
L
V
K
Site 94
S768
L
V
K
F
W
N
S
S
D
K
E
K
I
I
R
Site 95
S777
K
E
K
I
I
R
A
S
R
E
R
R
E
I
T
Site 96
T784
S
R
E
R
R
E
I
T
Y
Q
G
T
R
I
R
Site 97
Y785
R
E
R
R
E
I
T
Y
Q
G
T
R
I
R
L
Site 98
T793
Q
G
T
R
I
R
L
T
A
D
L
S
L
D
T
Site 99
T800
T
A
D
L
S
L
D
T
L
D
A
R
S
K
W
Site 100
Y825
G
F
N
P
R
I
L
Y
P
A
K
M
A
F
D
Site 101
S842
G
K
T
K
V
F
L
S
I
E
E
F
R
D
Y
Site 102
Y849
S
I
E
E
F
R
D
Y
V
L
H
M
P
T
L
Site 103
T855
D
Y
V
L
H
M
P
T
L
R
E
L
L
G
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation