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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C1orf59
Full Name:
UPF0486 protein C1orf59
Alias:
Type:
Mass (Da):
44525
Number AA:
393
UniProt ID:
Q5T8I9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
E
N
N
L
Q
C
S
S
V
V
D
G
N
F
E
Site 2
T23
F
E
E
V
P
R
E
T
A
I
Q
F
K
P
P
Site 3
Y32
I
Q
F
K
P
P
L
Y
R
Q
R
Y
Q
F
V
Site 4
Y36
P
P
L
Y
R
Q
R
Y
Q
F
V
K
N
L
V
Site 5
S90
K
L
R
W
R
G
D
S
L
A
P
F
L
G
D
Site 6
T107
K
P
R
D
L
N
L
T
I
T
L
Y
H
G
S
Site 7
S114
T
I
T
L
Y
H
G
S
V
V
E
R
D
S
R
Site 8
S120
G
S
V
V
E
R
D
S
R
L
L
G
F
D
L
Site 9
S139
E
L
I
E
H
L
D
S
G
D
L
A
R
F
P
Site 10
S161
S
P
S
M
I
V
I
S
T
P
N
S
E
F
N
Site 11
T162
P
S
M
I
V
I
S
T
P
N
S
E
F
N
P
Site 12
S173
E
F
N
P
L
F
P
S
V
T
L
R
D
S
D
Site 13
T175
N
P
L
F
P
S
V
T
L
R
D
S
D
H
K
Site 14
S179
P
S
V
T
L
R
D
S
D
H
K
F
E
W
T
Site 15
Y196
E
F
Q
T
W
A
L
Y
V
A
N
R
Y
D
Y
Site 16
Y203
Y
V
A
N
R
Y
D
Y
S
V
E
F
T
G
V
Site 17
S204
V
A
N
R
Y
D
Y
S
V
E
F
T
G
V
G
Site 18
T208
Y
D
Y
S
V
E
F
T
G
V
G
E
P
P
A
Site 19
T237
R
K
N
G
G
K
A
T
E
S
C
L
S
E
Q
Site 20
S239
N
G
G
K
A
T
E
S
C
L
S
E
Q
H
D
Site 21
S242
K
A
T
E
S
C
L
S
E
Q
H
D
Q
H
V
Site 22
Y250
E
Q
H
D
Q
H
V
Y
K
A
V
F
T
T
S
Site 23
T256
V
Y
K
A
V
F
T
T
S
Y
P
S
L
Q
Q
Site 24
Y258
K
A
V
F
T
T
S
Y
P
S
L
Q
Q
E
R
Site 25
S260
V
F
T
T
S
Y
P
S
L
Q
Q
E
R
F
F
Site 26
S281
E
V
S
Q
Q
V
E
S
L
R
V
S
H
L
P
Site 27
S285
Q
V
E
S
L
R
V
S
H
L
P
R
R
K
E
Site 28
S307
K
P
K
D
I
G
G
S
K
A
P
V
P
C
F
Site 29
S329
E
K
A
K
I
E
N
S
P
T
P
F
C
V
G
Site 30
T331
A
K
I
E
N
S
P
T
P
F
C
V
G
D
K
Site 31
Y349
P
L
Q
R
L
L
A
Y
P
K
L
N
R
L
C
Site 32
S364
A
N
E
E
M
M
R
S
V
I
A
D
S
I
P
Site 33
Y386
V
V
A
D
L
R
N
Y
F
D
E
Q
F
E
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation