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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PIP5KL1
Full Name:
Phosphatidylinositol-4-phosphate 5-kinase-like protein 1
Alias:
Type:
Mass (Da):
44572
Number AA:
394
UniProt ID:
Q5T9C9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
A
A
P
S
P
G
P
R
E
V
L
Site 2
S15
P
R
E
V
L
A
P
S
P
E
A
G
C
R
A
Site 3
T24
E
A
G
C
R
A
V
T
S
S
R
R
G
L
L
Site 4
S25
A
G
C
R
A
V
T
S
S
R
R
G
L
L
W
Site 5
S26
G
C
R
A
V
T
S
S
R
R
G
L
L
W
R
Site 6
S39
W
R
L
R
D
K
Q
S
R
L
G
L
F
E
I
Site 7
S47
R
L
G
L
F
E
I
S
P
G
H
E
L
H
G
Site 8
T76
V
S
M
D
H
P
P
T
G
P
P
S
R
D
D
Site 9
S80
H
P
P
T
G
P
P
S
R
D
D
F
S
E
V
Site 10
S85
P
P
S
R
D
D
F
S
E
V
L
T
Q
V
H
Site 11
T89
D
D
F
S
E
V
L
T
Q
V
H
E
G
F
E
Site 12
S111
A
F
A
W
L
R
R
S
L
G
L
A
E
E
D
Site 13
Y119
L
G
L
A
E
E
D
Y
Q
A
A
L
G
P
G
Site 14
S134
G
P
Y
L
Q
F
L
S
T
S
K
S
K
A
S
Site 15
T135
P
Y
L
Q
F
L
S
T
S
K
S
K
A
S
F
Site 16
S136
Y
L
Q
F
L
S
T
S
K
S
K
A
S
F
F
Site 17
S138
Q
F
L
S
T
S
K
S
K
A
S
F
F
L
S
Site 18
S141
S
T
S
K
S
K
A
S
F
F
L
S
H
D
Q
Site 19
S145
S
K
A
S
F
F
L
S
H
D
Q
R
F
F
L
Site 20
T154
D
Q
R
F
F
L
K
T
Q
G
R
R
E
V
Q
Site 21
Y170
L
L
A
H
L
P
R
Y
V
Q
H
L
Q
R
H
Site 22
S180
H
L
Q
R
H
P
H
S
L
L
A
R
L
L
G
Site 23
S190
A
R
L
L
G
V
H
S
L
R
V
D
R
G
K
Site 24
T199
R
V
D
R
G
K
K
T
Y
F
I
V
M
Q
S
Site 25
Y200
V
D
R
G
K
K
T
Y
F
I
V
M
Q
S
V
Site 26
S215
F
Y
P
A
G
R
I
S
E
R
Y
D
I
K
G
Site 27
Y218
A
G
R
I
S
E
R
Y
D
I
K
G
C
E
V
Site 28
S226
D
I
K
G
C
E
V
S
R
W
V
D
P
A
P
Site 29
T270
R
Q
M
E
L
D
T
T
F
L
R
E
L
N
V
Site 30
S298
E
D
E
R
G
P
G
S
S
L
I
F
R
T
A
Site 31
S299
D
E
R
G
P
G
S
S
L
I
F
R
T
A
R
Site 32
S313
R
S
V
Q
G
A
Q
S
P
E
E
S
R
A
Q
Site 33
S317
G
A
Q
S
P
E
E
S
R
A
Q
N
R
R
L
Site 34
Y342
L
D
G
P
E
Q
R
Y
F
L
G
V
V
D
L
Site 35
T351
L
G
V
V
D
L
A
T
V
Y
G
L
R
K
R
Site 36
Y353
V
V
D
L
A
T
V
Y
G
L
R
K
R
L
E
Site 37
T365
R
L
E
H
L
W
K
T
L
R
Y
P
G
R
T
Site 38
Y368
H
L
W
K
T
L
R
Y
P
G
R
T
F
S
T
Site 39
T372
T
L
R
Y
P
G
R
T
F
S
T
V
S
P
A
Site 40
S374
R
Y
P
G
R
T
F
S
T
V
S
P
A
R
Y
Site 41
T375
Y
P
G
R
T
F
S
T
V
S
P
A
R
Y
A
Site 42
S377
G
R
T
F
S
T
V
S
P
A
R
Y
A
R
R
Site 43
Y381
S
T
V
S
P
A
R
Y
A
R
R
L
C
Q
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation