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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GPR177
Full Name:
Protein wntless homolog
Alias:
Protein wntless homologue
Type:
Mass (Da):
62235
Number AA:
541
UniProt ID:
Q5T9L3
International Prot ID:
IPI00384961
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016020
GO:0016021
GO:0031224
Uniprot
OncoNet
Molecular Function:
GO:0004871
GO:0060089
GO:0004871
PhosphoSite+
KinaseNET
Biological Process:
GO:0009966
GO:0009967
GO:0043122
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
A
I
I
E
N
M
S
T
K
K
L
C
I
V
G
Site 2
S133
I
R
E
N
A
E
V
S
M
D
V
S
L
A
Y
Site 3
S137
A
E
V
S
M
D
V
S
L
A
Y
R
D
D
A
Site 4
T163
V
P
R
K
L
K
C
T
F
T
S
P
K
T
P
Site 5
T165
R
K
L
K
C
T
F
T
S
P
K
T
P
E
H
Site 6
S166
K
L
K
C
T
F
T
S
P
K
T
P
E
H
E
Site 7
T169
C
T
F
T
S
P
K
T
P
E
H
E
G
R
Y
Site 8
Y177
P
E
H
E
G
R
Y
Y
E
C
D
V
L
P
F
Site 9
T257
V
W
Y
W
R
R
I
T
M
M
S
R
P
P
V
Site 10
S260
W
R
R
I
T
M
M
S
R
P
P
V
L
L
E
Site 11
Y335
E
R
N
H
I
A
G
Y
W
K
Q
V
G
P
I
Site 12
S408
F
Q
V
F
R
N
I
S
G
K
Q
S
S
L
P
Site 13
S412
R
N
I
S
G
K
Q
S
S
L
P
A
M
S
K
Site 14
S413
N
I
S
G
K
Q
S
S
L
P
A
M
S
K
V
Site 15
S418
Q
S
S
L
P
A
M
S
K
V
R
R
L
H
Y
Site 16
Y425
S
K
V
R
R
L
H
Y
E
G
L
I
F
R
F
Site 17
Y499
Y
A
P
S
H
K
N
Y
G
E
D
Q
S
N
G
Site 18
S504
K
N
Y
G
E
D
Q
S
N
G
D
L
G
V
H
Site 19
S512
N
G
D
L
G
V
H
S
G
E
E
L
Q
L
T
Site 20
T519
S
G
E
E
L
Q
L
T
T
T
I
T
H
V
D
Site 21
T523
L
Q
L
T
T
T
I
T
H
V
D
G
P
T
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation