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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC9A11
Full Name:
Sodium/hydrogen exchanger 11
Alias:
MGC43026; Na(+)/H(+) exchanger 11; RP3-436N22.2; S9A11; Solute carrier family 9 member 11; Solute carrier family 9, member 11
Type:
Mass (Da):
129050
Number AA:
UniProt ID:
Q5TAH2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005216
GO:0031402
GO:0015299
PhosphoSite+
KinaseNET
Biological Process:
GO:0006814
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y24
L
C
G
Q
P
A
D
Y
L
V
E
E
K
H
F
Site 2
T33
V
E
E
K
H
F
T
T
L
V
C
F
I
V
V
Site 3
S89
Y
P
L
L
R
T
S
S
F
S
L
Y
S
Y
F
Site 4
S91
L
L
R
T
S
S
F
S
L
Y
S
Y
F
S
P
Site 5
Y93
R
T
S
S
F
S
L
Y
S
Y
F
S
P
L
I
Site 6
S129
L
T
G
L
I
S
F
S
T
A
S
I
I
I
G
Site 7
T130
T
G
L
I
S
F
S
T
A
S
I
I
I
G
Y
Site 8
S132
L
I
S
F
S
T
A
S
I
I
I
G
Y
V
V
Site 9
Y137
T
A
S
I
I
I
G
Y
V
V
I
K
F
N
K
Site 10
S151
K
D
S
W
D
L
Q
S
C
L
L
F
S
I
T
Site 11
S170
D
P
L
R
S
V
N
S
L
K
T
I
G
I
S
Site 12
T173
R
S
V
N
S
L
K
T
I
G
I
S
K
I
Y
Site 13
T290
G
L
N
L
D
S
L
T
F
K
P
K
I
E
L
Site 14
S308
K
F
L
R
I
F
S
S
V
Y
E
H
L
I
Y
Site 15
Y310
L
R
I
F
S
S
V
Y
E
H
L
I
Y
A
F
Site 16
Y330
G
C
G
E
L
S
H
Y
E
F
H
T
I
P
F
Site 17
T417
V
Q
V
I
S
L
L
T
M
G
I
N
S
Y
V
Site 18
Y423
L
T
M
G
I
N
S
Y
V
M
T
Q
S
A
R
Site 19
T426
G
I
N
S
Y
V
M
T
Q
S
A
R
K
L
D
Site 20
S428
N
S
Y
V
M
T
Q
S
A
R
K
L
D
L
C
Site 21
Y485
E
D
K
T
R
I
E
Y
I
P
F
S
H
V
S
Site 22
T498
V
S
H
N
D
M
K
T
E
S
T
T
D
E
A
Site 23
S500
H
N
D
M
K
T
E
S
T
T
D
E
A
L
M
Site 24
S521
V
A
A
I
Q
M
S
S
F
E
K
Q
R
N
N
Site 25
S555
S
I
Q
G
K
F
M
S
I
Y
D
V
S
T
Y
Site 26
Y557
Q
G
K
F
M
S
I
Y
D
V
S
T
Y
M
R
Site 27
Y562
S
I
Y
D
V
S
T
Y
M
R
T
R
S
W
L
Site 28
Y645
S
A
L
I
S
I
N
Y
Y
F
M
F
L
Y
V
Site 29
Y646
A
L
I
S
I
N
Y
Y
F
M
F
L
Y
V
L
Site 30
Y651
N
Y
Y
F
M
F
L
Y
V
L
E
S
T
L
K
Site 31
S740
V
Q
I
K
K
R
L
S
L
M
Y
S
I
T
K
Site 32
Y743
K
K
R
L
S
L
M
Y
S
I
T
K
G
Y
I
Site 33
S744
K
R
L
S
L
M
Y
S
I
T
K
G
Y
I
K
Site 34
T746
L
S
L
M
Y
S
I
T
K
G
Y
I
K
S
Q
Site 35
S752
I
T
K
G
Y
I
K
S
Q
E
D
A
K
L
L
Site 36
T779
K
L
C
E
I
L
E
T
N
K
Q
D
A
V
K
Site 37
T858
P
K
A
I
P
P
P
T
P
D
I
Y
L
H
N
Site 38
T893
A
C
F
D
S
G
D
T
I
C
K
G
G
E
M
Site 39
T920
I
L
H
S
L
S
P
T
F
G
I
E
S
N
Q
Site 40
T938
R
G
S
R
D
M
F
T
E
F
C
T
T
G
D
Site 41
T961
L
K
R
E
I
E
Y
T
V
I
C
E
T
S
L
Site 42
Y1003
K
L
A
L
S
T
A
Y
Q
Y
F
E
S
S
L
Site 43
Y1005
A
L
S
T
A
Y
Q
Y
F
E
S
S
L
I
D
Site 44
T1057
V
Y
G
S
V
I
D
T
K
T
E
E
P
Y
F
Site 45
T1059
G
S
V
I
D
T
K
T
E
E
P
Y
F
A
P
Site 46
Y1063
D
T
K
T
E
E
P
Y
F
A
P
C
I
I
P
Site 47
S1091
K
L
L
I
I
Q
A
S
E
L
T
Q
R
N
S
Site 48
T1094
I
I
Q
A
S
E
L
T
Q
R
N
S
N
T
N
Site 49
S1098
S
E
L
T
Q
R
N
S
N
T
N
V
M
A
S
Site 50
T1100
L
T
Q
R
N
S
N
T
N
V
M
A
S
V
N
Site 51
T1108
N
V
M
A
S
V
N
T
V
F
E
Q
P
G
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation