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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WDR42A
Full Name:
DDB1- and CUL4-associated factor 8
Alias:
DDB1 and CUL4 associated factor 8; DKFZp781G1096; FLJ35857; H326; MGC117276; MGC118891; MGC99640; WD repeat domain 42A; WD42A
Type:
Mass (Da):
66852
Number AA:
597
UniProt ID:
Q5TAQ9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
S
S
K
G
S
S
T
D
G
R
T
D
Site 2
S7
_
M
S
S
K
G
S
S
T
D
G
R
T
D
L
Site 3
T12
G
S
S
T
D
G
R
T
D
L
A
N
G
S
L
Site 4
S18
R
T
D
L
A
N
G
S
L
S
S
S
P
E
E
Site 5
S20
D
L
A
N
G
S
L
S
S
S
P
E
E
M
S
Site 6
S22
A
N
G
S
L
S
S
S
P
E
E
M
S
G
A
Site 7
S27
S
S
S
P
E
E
M
S
G
A
E
E
G
R
E
Site 8
T35
G
A
E
E
G
R
E
T
S
S
G
I
E
V
E
Site 9
S36
A
E
E
G
R
E
T
S
S
G
I
E
V
E
A
Site 10
S47
E
V
E
A
S
D
L
S
L
S
L
T
G
D
D
Site 11
S49
E
A
S
D
L
S
L
S
L
T
G
D
D
G
G
Site 12
T51
S
D
L
S
L
S
L
T
G
D
D
G
G
P
N
Site 13
S61
D
G
G
P
N
R
T
S
T
E
S
R
G
T
D
Site 14
T62
G
G
P
N
R
T
S
T
E
S
R
G
T
D
T
Site 15
S64
P
N
R
T
S
T
E
S
R
G
T
D
T
E
S
Site 16
T67
T
S
T
E
S
R
G
T
D
T
E
S
S
G
E
Site 17
T69
T
E
S
R
G
T
D
T
E
S
S
G
E
D
K
Site 18
S72
R
G
T
D
T
E
S
S
G
E
D
K
D
S
D
Site 19
S78
S
S
G
E
D
K
D
S
D
S
M
E
D
T
G
Site 20
S80
G
E
D
K
D
S
D
S
M
E
D
T
G
H
Y
Site 21
T84
D
S
D
S
M
E
D
T
G
H
Y
S
I
N
D
Site 22
S99
E
N
R
V
H
D
R
S
E
E
E
E
E
E
E
Site 23
S129
R
A
N
R
D
Q
D
S
S
D
D
E
R
A
L
Site 24
S130
A
N
R
D
Q
D
S
S
D
D
E
R
A
L
E
Site 25
S141
R
A
L
E
D
W
V
S
S
E
T
S
A
L
P
Site 26
S142
A
L
E
D
W
V
S
S
E
T
S
A
L
P
R
Site 27
T144
E
D
W
V
S
S
E
T
S
A
L
P
R
P
R
Site 28
S145
D
W
V
S
S
E
T
S
A
L
P
R
P
R
W
Site 29
S165
L
R
E
R
E
L
G
S
S
A
R
F
V
Y
E
Site 30
S166
R
E
R
E
L
G
S
S
A
R
F
V
Y
E
A
Site 31
T206
L
H
F
N
Q
R
G
T
W
L
A
S
G
S
D
Site 32
S210
Q
R
G
T
W
L
A
S
G
S
D
D
L
K
V
Site 33
S233
Q
P
V
L
D
F
E
S
G
H
K
S
N
V
F
Site 34
S237
D
F
E
S
G
H
K
S
N
V
F
Q
A
K
F
Site 35
S248
Q
A
K
F
L
P
N
S
G
D
S
T
L
A
M
Site 36
T252
L
P
N
S
G
D
S
T
L
A
M
C
A
R
D
Site 37
S268
Q
V
R
V
A
E
L
S
A
T
Q
C
C
K
N
Site 38
T270
R
V
A
E
L
S
A
T
Q
C
C
K
N
T
K
Site 39
T298
L
E
P
D
S
P
C
T
F
L
S
A
G
E
D
Site 40
S320
L
R
Q
D
R
P
A
S
K
L
V
V
T
K
E
Site 41
T336
E
K
K
V
G
L
Y
T
I
Y
V
N
P
A
N
Site 42
Y338
K
V
G
L
Y
T
I
Y
V
N
P
A
N
T
H
Site 43
Y359
R
D
Q
F
V
R
I
Y
D
Q
R
K
I
D
E
Site 44
T391
S
E
S
K
A
N
I
T
C
L
V
Y
S
H
D
Site 45
T400
L
V
Y
S
H
D
G
T
E
L
L
A
S
Y
N
Site 46
S405
D
G
T
E
L
L
A
S
Y
N
D
E
D
I
Y
Site 47
Y412
S
Y
N
D
E
D
I
Y
L
F
N
S
S
H
S
Site 48
Y424
S
H
S
D
G
A
Q
Y
V
K
R
Y
K
G
H
Site 49
T436
K
G
H
R
N
N
A
T
V
K
G
V
N
F
Y
Site 50
Y443
T
V
K
G
V
N
F
Y
G
P
K
S
E
F
V
Site 51
S447
V
N
F
Y
G
P
K
S
E
F
V
V
S
G
S
Site 52
S452
P
K
S
E
F
V
V
S
G
S
D
C
G
H
I
Site 53
T516
A
E
A
S
T
E
L
T
G
L
K
D
V
I
K
Site 54
S533
K
R
E
R
D
E
D
S
L
H
Q
T
D
L
F
Site 55
T537
D
E
D
S
L
H
Q
T
D
L
F
D
S
H
M
Site 56
S573
V
G
A
T
D
A
D
S
D
E
S
P
S
S
S
Site 57
S576
T
D
A
D
S
D
E
S
P
S
S
S
D
T
S
Site 58
S578
A
D
S
D
E
S
P
S
S
S
D
T
S
D
E
Site 59
S579
D
S
D
E
S
P
S
S
S
D
T
S
D
E
E
Site 60
S580
S
D
E
S
P
S
S
S
D
T
S
D
E
E
E
Site 61
T582
E
S
P
S
S
S
D
T
S
D
E
E
E
G
P
Site 62
S583
S
P
S
S
S
D
T
S
D
E
E
E
G
P
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation