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Updated November 2019
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Protein Info
Short Name:
ZCCHC11
Full Name:
Terminal uridylyltransferase 4
Alias:
KIAA0191; PAP associated domain containing 3; PAPD3; ZCH11; Zinc finger CCHC domain containing protein 11; Zinc finger CCHC domain-containing protein 11; Zinc finger, CCHC domain containing 11
Type:
Unknown function
Mass (Da):
185166
Number AA:
1644
UniProt ID:
Q5TAX3
International Prot ID:
IPI00289861
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0050265
GO:0003676
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0031123
GO:0010587
GO:0031054
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
E
E
S
K
T
L
K
S
E
N
H
E
Site 2
S9
E
E
S
K
T
L
K
S
E
N
H
E
P
K
K
Site 3
S41
L
K
A
R
N
D
K
S
V
K
E
I
E
N
S
Site 4
S48
S
V
K
E
I
E
N
S
S
P
N
R
N
S
S
Site 5
S49
V
K
E
I
E
N
S
S
P
N
R
N
S
S
K
Site 6
S54
N
S
S
P
N
R
N
S
S
K
K
N
K
Q
N
Site 7
S55
S
S
P
N
R
N
S
S
K
K
N
K
Q
N
D
Site 8
T68
N
D
I
C
I
E
K
T
E
V
K
S
C
K
V
Site 9
S94
G
L
V
L
R
D
Q
S
H
C
K
A
K
K
F
Site 10
S104
K
A
K
K
F
P
N
S
P
V
K
A
E
K
A
Site 11
S114
K
A
E
K
A
T
I
S
Q
A
K
S
E
K
A
Site 12
S118
A
T
I
S
Q
A
K
S
E
K
A
T
S
L
Q
Site 13
S123
A
K
S
E
K
A
T
S
L
Q
A
K
A
E
K
Site 14
S131
L
Q
A
K
A
E
K
S
P
K
S
P
N
S
V
Site 15
S134
K
A
E
K
S
P
K
S
P
N
S
V
K
A
E
Site 16
S137
K
S
P
K
S
P
N
S
V
K
A
E
K
A
S
Site 17
S145
V
K
A
E
K
A
S
S
Y
Q
M
K
S
E
K
Site 18
Y146
K
A
E
K
A
S
S
Y
Q
M
K
S
E
K
V
Site 19
S150
A
S
S
Y
Q
M
K
S
E
K
V
P
S
S
P
Site 20
S155
M
K
S
E
K
V
P
S
S
P
A
E
A
E
K
Site 21
S156
K
S
E
K
V
P
S
S
P
A
E
A
E
K
G
Site 22
S165
A
E
A
E
K
G
P
S
L
L
L
K
D
M
R
Site 23
T175
L
K
D
M
R
Q
K
T
E
L
Q
Q
I
G
K
Site 24
S187
I
G
K
K
I
P
S
S
F
T
S
V
D
K
V
Site 25
S190
K
I
P
S
S
F
T
S
V
D
K
V
N
I
E
Site 26
S209
E
K
C
A
L
Q
N
S
P
R
S
Q
K
Q
Q
Site 27
S212
A
L
Q
N
S
P
R
S
Q
K
Q
Q
T
C
T
Site 28
T217
P
R
S
Q
K
Q
Q
T
C
T
D
N
T
G
D
Site 29
S225
C
T
D
N
T
G
D
S
D
D
S
A
S
G
I
Site 30
S228
N
T
G
D
S
D
D
S
A
S
G
I
E
D
V
Site 31
S230
G
D
S
D
D
S
A
S
G
I
E
D
V
S
D
Site 32
S236
A
S
G
I
E
D
V
S
D
D
L
S
K
M
K
Site 33
S240
E
D
V
S
D
D
L
S
K
M
K
N
D
E
S
Site 34
S247
S
K
M
K
N
D
E
S
N
K
E
N
S
S
E
Site 35
Y257
E
N
S
S
E
M
D
Y
L
E
N
A
T
V
I
Site 36
T270
V
I
D
E
S
A
L
T
P
E
Q
R
L
G
L
Site 37
S296
I
F
R
L
E
K
R
S
P
E
Y
T
N
C
R
Site 38
Y299
L
E
K
R
S
P
E
Y
T
N
C
R
Y
L
C
Site 39
T300
E
K
R
S
P
E
Y
T
N
C
R
Y
L
C
K
Site 40
S339
I
L
E
K
Q
E
E
S
E
L
R
S
L
P
P
Site 41
S343
Q
E
E
S
E
L
R
S
L
P
P
P
S
P
A
Site 42
T369
L
A
K
E
H
G
I
T
D
D
D
L
R
V
R
Site 43
T388
E
E
M
S
K
V
I
T
T
F
L
P
E
C
S
Site 44
S395
T
T
F
L
P
E
C
S
L
R
L
Y
G
S
S
Site 45
Y399
P
E
C
S
L
R
L
Y
G
S
S
L
T
R
F
Site 46
S402
S
L
R
L
Y
G
S
S
L
T
R
F
A
L
K
Site 47
Y508
R
Y
W
A
K
L
C
Y
I
D
S
Q
T
D
G
Site 48
S511
A
K
L
C
Y
I
D
S
Q
T
D
G
G
I
P
Site 49
T513
L
C
Y
I
D
S
Q
T
D
G
G
I
P
S
Y
Site 50
S574
F
V
K
W
E
C
N
S
S
S
A
T
E
K
N
Site 51
S575
V
K
W
E
C
N
S
S
S
A
T
E
K
N
S
Site 52
S576
K
W
E
C
N
S
S
S
A
T
E
K
N
S
I
Site 53
T578
E
C
N
S
S
S
A
T
E
K
N
S
I
A
E
Site 54
T598
A
D
Q
P
K
D
D
T
K
K
T
E
T
D
N
Site 55
T601
P
K
D
D
T
K
K
T
E
T
D
N
Q
S
N
Site 56
T603
D
D
T
K
K
T
E
T
D
N
Q
S
N
A
M
Site 57
S607
K
T
E
T
D
N
Q
S
N
A
M
K
E
K
H
Site 58
S617
M
K
E
K
H
G
K
S
P
L
A
L
E
T
P
Site 59
T623
K
S
P
L
A
L
E
T
P
N
R
V
S
L
G
Site 60
S628
L
E
T
P
N
R
V
S
L
G
Q
L
W
L
E
Site 61
T660
V
R
I
Q
D
I
L
T
R
E
N
K
N
W
P
Site 62
S678
I
A
I
E
D
P
F
S
V
K
R
N
V
A
R
Site 63
S686
V
K
R
N
V
A
R
S
L
N
S
Q
L
V
Y
Site 64
Y693
S
L
N
S
Q
L
V
Y
E
Y
V
V
E
R
F
Site 65
Y695
N
S
Q
L
V
Y
E
Y
V
V
E
R
F
R
A
Site 66
Y704
V
E
R
F
R
A
A
Y
R
Y
F
A
C
P
Q
Site 67
Y706
R
F
R
A
A
Y
R
Y
F
A
C
P
Q
T
K
Site 68
S718
Q
T
K
G
G
N
K
S
T
V
D
F
K
K
R
Site 69
T719
T
K
G
G
N
K
S
T
V
D
F
K
K
R
E
Site 70
S738
S
N
K
K
P
V
K
S
N
N
M
A
T
N
G
Site 71
S773
C
D
E
M
D
C
T
S
Q
R
C
I
I
D
N
Site 72
S797
F
A
D
H
G
Q
D
S
S
S
L
S
T
S
K
Site 73
S798
A
D
H
G
Q
D
S
S
S
L
S
T
S
K
S
Site 74
S799
D
H
G
Q
D
S
S
S
L
S
T
S
K
S
S
Site 75
S801
G
Q
D
S
S
S
L
S
T
S
K
S
S
E
I
Site 76
T802
Q
D
S
S
S
L
S
T
S
K
S
S
E
I
E
Site 77
S803
D
S
S
S
L
S
T
S
K
S
S
E
I
E
P
Site 78
S805
S
S
L
S
T
S
K
S
S
E
I
E
P
K
L
Site 79
S831
T
C
L
K
K
E
L
S
Q
C
N
C
I
D
L
Site 80
S839
Q
C
N
C
I
D
L
S
K
S
P
D
P
D
K
Site 81
S841
N
C
I
D
L
S
K
S
P
D
P
D
K
S
T
Site 82
S847
K
S
P
D
P
D
K
S
T
G
T
D
C
R
S
Site 83
T848
S
P
D
P
D
K
S
T
G
T
D
C
R
S
N
Site 84
T850
D
P
D
K
S
T
G
T
D
C
R
S
N
L
E
Site 85
S854
S
T
G
T
D
C
R
S
N
L
E
T
E
S
S
Site 86
T858
D
C
R
S
N
L
E
T
E
S
S
H
Q
S
V
Site 87
S860
R
S
N
L
E
T
E
S
S
H
Q
S
V
C
T
Site 88
S861
S
N
L
E
T
E
S
S
H
Q
S
V
C
T
D
Site 89
S864
E
T
E
S
S
H
Q
S
V
C
T
D
T
S
A
Site 90
T867
S
S
H
Q
S
V
C
T
D
T
S
A
T
S
C
Site 91
T869
H
Q
S
V
C
T
D
T
S
A
T
S
C
N
C
Site 92
Y897
N
L
P
T
Q
E
L
Y
Y
V
F
D
K
F
I
Site 93
T944
L
K
P
L
P
P
M
T
N
R
F
R
E
I
L
Site 94
S963
K
R
C
F
D
E
L
S
P
P
C
S
E
Q
H
Site 95
S967
D
E
L
S
P
P
C
S
E
Q
H
N
R
E
Q
Site 96
S999
R
L
C
L
F
G
S
S
K
N
G
F
G
F
R
Site 97
T1015
S
D
L
D
I
C
M
T
L
E
G
H
E
N
A
Site 98
S1065
V
K
F
E
H
R
R
S
G
L
E
G
D
I
S
Site 99
S1072
S
G
L
E
G
D
I
S
L
Y
N
T
L
A
Q
Site 100
Y1074
L
E
G
D
I
S
L
Y
N
T
L
A
Q
H
N
Site 101
T1076
G
D
I
S
L
Y
N
T
L
A
Q
H
N
T
R
Site 102
Y1088
N
T
R
M
L
A
T
Y
A
A
I
D
P
R
V
Site 103
Y1097
A
I
D
P
R
V
Q
Y
L
G
Y
T
M
K
V
Site 104
Y1100
P
R
V
Q
Y
L
G
Y
T
M
K
V
F
A
K
Site 105
T1101
R
V
Q
Y
L
G
Y
T
M
K
V
F
A
K
R
Site 106
S1115
R
C
D
I
G
D
A
S
R
G
S
L
S
S
Y
Site 107
S1118
I
G
D
A
S
R
G
S
L
S
S
Y
A
Y
I
Site 108
T1168
N
A
F
F
F
D
K
T
E
E
L
K
K
R
L
Site 109
S1177
E
L
K
K
R
L
P
S
L
G
K
N
T
E
S
Site 110
S1184
S
L
G
K
N
T
E
S
L
G
E
L
W
L
G
Site 111
Y1196
W
L
G
L
L
R
F
Y
T
E
E
F
D
F
K
Site 112
T1197
L
G
L
L
R
F
Y
T
E
E
F
D
F
K
E
Site 113
Y1205
E
E
F
D
F
K
E
Y
V
I
S
I
R
Q
K
Site 114
S1208
D
F
K
E
Y
V
I
S
I
R
Q
K
K
L
L
Site 115
T1217
R
Q
K
K
L
L
T
T
F
E
K
Q
W
T
S
Site 116
T1264
N
G
R
K
L
F
G
T
P
F
Y
P
L
I
G
Site 117
T1284
F
F
D
S
R
V
L
T
D
G
E
L
A
P
N
Site 118
Y1304
V
C
G
K
I
G
H
Y
M
K
D
C
P
K
R
Site 119
S1313
K
D
C
P
K
R
K
S
L
L
F
R
L
K
K
Site 120
S1323
F
R
L
K
K
K
D
S
E
E
E
K
E
G
N
Site 121
S1336
G
N
E
E
E
K
D
S
R
D
V
L
D
P
R
Site 122
T1348
D
P
R
D
L
H
D
T
R
D
F
R
D
P
R
Site 123
S1383
K
L
A
R
Q
R
N
S
S
V
A
A
A
Q
L
Site 124
S1384
L
A
R
Q
R
N
S
S
V
A
A
A
Q
L
V
Site 125
S1411
A
Q
Q
Q
G
D
Q
S
I
R
T
R
Q
S
S
Site 126
T1414
Q
G
D
Q
S
I
R
T
R
Q
S
S
E
C
S
Site 127
S1417
Q
S
I
R
T
R
Q
S
S
E
C
S
E
S
P
Site 128
S1418
S
I
R
T
R
Q
S
S
E
C
S
E
S
P
S
Site 129
S1421
T
R
Q
S
S
E
C
S
E
S
P
S
Y
S
P
Site 130
S1423
Q
S
S
E
C
S
E
S
P
S
Y
S
P
Q
P
Site 131
S1425
S
E
C
S
E
S
P
S
Y
S
P
Q
P
Q
P
Site 132
Y1426
E
C
S
E
S
P
S
Y
S
P
Q
P
Q
P
F
Site 133
S1427
C
S
E
S
P
S
Y
S
P
Q
P
Q
P
F
P
Site 134
S1437
P
Q
P
F
P
Q
N
S
S
Q
S
A
A
I
T
Site 135
S1438
Q
P
F
P
Q
N
S
S
Q
S
A
A
I
T
Q
Site 136
T1444
S
S
Q
S
A
A
I
T
Q
P
S
S
Q
P
G
Site 137
S1447
S
A
A
I
T
Q
P
S
S
Q
P
G
S
Q
P
Site 138
S1448
A
A
I
T
Q
P
S
S
Q
P
G
S
Q
P
K
Site 139
S1452
Q
P
S
S
Q
P
G
S
Q
P
K
L
G
P
P
Site 140
Y1474
H
Q
V
Q
M
P
L
Y
N
F
P
Q
S
P
P
Site 141
S1479
P
L
Y
N
F
P
Q
S
P
P
A
Q
Y
S
P
Site 142
S1485
Q
S
P
P
A
Q
Y
S
P
M
H
N
M
G
L
Site 143
S1514
I
H
G
P
V
I
H
S
A
P
G
S
A
P
S
Site 144
S1521
S
A
P
G
S
A
P
S
N
I
G
L
N
D
P
Site 145
T1545
R
P
V
A
I
P
N
T
S
H
D
G
H
W
P
Site 146
T1554
H
D
G
H
W
P
R
T
V
A
P
N
S
L
V
Site 147
S1563
A
P
N
S
L
V
N
S
G
A
V
G
N
S
E
Site 148
S1569
N
S
G
A
V
G
N
S
E
P
G
F
R
G
L
Site 149
T1577
E
P
G
F
R
G
L
T
P
P
I
P
W
E
H
Site 150
Y1620
F
Q
P
N
K
P
F
Y
T
Q
D
R
C
A
T
Site 151
T1627
Y
T
Q
D
R
C
A
T
R
R
C
R
E
R
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation