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Updated November 2019
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Protein Info
Short Name:
KIAA1009
Full Name:
Protein QN1 homolog
Alias:
Type:
Mass (Da):
161943
Number AA:
1403
UniProt ID:
Q5TB80
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S21
E
Q
F
M
K
E
L
S
D
D
S
F
E
N
S
Site 2
S24
M
K
E
L
S
D
D
S
F
E
N
S
D
K
T
Site 3
S28
S
D
D
S
F
E
N
S
D
K
T
A
R
Q
S
Site 4
T31
S
F
E
N
S
D
K
T
A
R
Q
S
K
K
E
Site 5
S35
S
D
K
T
A
R
Q
S
K
K
E
M
K
K
K
Site 6
S65
G
L
L
G
T
N
V
S
Y
L
K
T
K
K
T
Site 7
T69
T
N
V
S
Y
L
K
T
K
K
T
S
Q
P
V
Site 8
T72
S
Y
L
K
T
K
K
T
S
Q
P
V
M
E
I
Site 9
S92
E
K
I
Q
F
L
K
S
S
G
T
S
L
L
S
Site 10
S93
K
I
Q
F
L
K
S
S
G
T
S
L
L
S
T
Site 11
T95
Q
F
L
K
S
S
G
T
S
L
L
S
T
D
S
Site 12
S99
S
S
G
T
S
L
L
S
T
D
S
L
E
T
N
Site 13
T100
S
G
T
S
L
L
S
T
D
S
L
E
T
N
E
Site 14
S102
T
S
L
L
S
T
D
S
L
E
T
N
E
L
V
Site 15
S111
E
T
N
E
L
V
V
S
E
L
N
H
S
S
L
Site 16
S117
V
S
E
L
N
H
S
S
L
G
V
G
L
D
T
Site 17
T124
S
L
G
V
G
L
D
T
L
E
E
Q
E
E
K
Site 18
T143
A
R
L
E
K
G
L
T
S
S
I
D
Y
S
R
Site 19
S144
R
L
E
K
G
L
T
S
S
I
D
Y
S
R
L
Site 20
S145
L
E
K
G
L
T
S
S
I
D
Y
S
R
L
N
Site 21
Y148
G
L
T
S
S
I
D
Y
S
R
L
N
K
E
L
Site 22
S149
L
T
S
S
I
D
Y
S
R
L
N
K
E
L
D
Site 23
S157
R
L
N
K
E
L
D
S
N
D
S
T
H
F
K
Site 24
S160
K
E
L
D
S
N
D
S
T
H
F
K
A
L
H
Site 25
T161
E
L
D
S
N
D
S
T
H
F
K
A
L
H
S
Site 26
S184
D
D
E
H
E
N
E
S
K
H
E
E
L
A
E
Site 27
S194
E
E
L
A
E
N
Y
S
D
D
F
E
D
E
Y
Site 28
Y201
S
D
D
F
E
D
E
Y
V
G
A
P
L
T
T
Site 29
T207
E
Y
V
G
A
P
L
T
T
K
D
E
E
M
P
Site 30
S215
T
K
D
E
E
M
P
S
K
E
N
S
K
S
E
Site 31
S219
E
M
P
S
K
E
N
S
K
S
E
K
I
S
V
Site 32
S221
P
S
K
E
N
S
K
S
E
K
I
S
V
P
K
Site 33
S225
N
S
K
S
E
K
I
S
V
P
K
Q
E
E
E
Site 34
T234
P
K
Q
E
E
E
K
T
G
M
L
A
N
V
V
Site 35
T261
L
D
E
Q
D
K
I
T
P
K
P
R
C
L
P
Site 36
T276
E
M
T
E
N
E
M
T
G
T
G
V
S
Y
G
Site 37
T278
T
E
N
E
M
T
G
T
G
V
S
Y
G
Q
S
Site 38
S281
E
M
T
G
T
G
V
S
Y
G
Q
S
S
S
D
Site 39
Y282
M
T
G
T
G
V
S
Y
G
Q
S
S
S
D
V
Site 40
S285
T
G
V
S
Y
G
Q
S
S
S
D
V
E
A
L
Site 41
S287
V
S
Y
G
Q
S
S
S
D
V
E
A
L
H
Q
Site 42
S313
E
D
K
Q
K
I
E
S
N
T
V
E
D
I
K
Site 43
T315
K
Q
K
I
E
S
N
T
V
E
D
I
K
S
S
Site 44
S321
N
T
V
E
D
I
K
S
S
V
K
G
H
P
Q
Site 45
S322
T
V
E
D
I
K
S
S
V
K
G
H
P
Q
E
Site 46
S338
E
E
N
S
K
N
I
S
T
M
E
S
D
L
P
Site 47
S342
K
N
I
S
T
M
E
S
D
L
P
T
V
E
E
Site 48
T346
T
M
E
S
D
L
P
T
V
E
E
L
M
K
P
Site 49
S358
M
K
P
I
R
I
D
S
F
G
I
S
G
F
D
Site 50
S370
G
F
D
L
Q
P
V
S
S
E
K
V
A
E
R
Site 51
T380
K
V
A
E
R
K
E
T
E
F
F
S
S
L
P
Site 52
S384
R
K
E
T
E
F
F
S
S
L
P
L
K
M
N
Site 53
S385
K
E
T
E
F
F
S
S
L
P
L
K
M
N
P
Site 54
S396
K
M
N
P
N
I
L
S
Q
D
S
Q
H
V
N
Site 55
S399
P
N
I
L
S
Q
D
S
Q
H
V
N
L
F
F
Site 56
T418
E
N
V
I
L
Q
K
T
T
N
E
S
M
E
N
Site 57
S422
L
Q
K
T
T
N
E
S
M
E
N
S
C
P
Q
Site 58
S426
T
N
E
S
M
E
N
S
C
P
Q
V
T
E
V
Site 59
T436
Q
V
T
E
V
T
A
T
E
E
H
V
D
K
M
Site 60
Y444
E
E
H
V
D
K
M
Y
L
N
I
L
R
K
K
Site 61
T453
N
I
L
R
K
K
I
T
V
N
S
S
S
L
S
Site 62
S456
R
K
K
I
T
V
N
S
S
S
L
S
Q
D
D
Site 63
S458
K
I
T
V
N
S
S
S
L
S
Q
D
D
K
I
Site 64
S460
T
V
N
S
S
S
L
S
Q
D
D
K
I
N
K
Site 65
T468
Q
D
D
K
I
N
K
T
Y
R
S
Q
L
S
S
Site 66
S471
K
I
N
K
T
Y
R
S
Q
L
S
S
E
E
E
Site 67
S474
K
T
Y
R
S
Q
L
S
S
E
E
E
G
A
V
Site 68
S475
T
Y
R
S
Q
L
S
S
E
E
E
G
A
V
M
Site 69
S493
V
P
Y
K
K
A
R
S
A
P
P
L
L
K
R
Site 70
S504
L
L
K
R
K
P
Q
S
G
L
Y
A
S
V
R
Site 71
Y507
R
K
P
Q
S
G
L
Y
A
S
V
R
S
S
G
Site 72
S509
P
Q
S
G
L
Y
A
S
V
R
S
S
G
Y
G
Site 73
S513
L
Y
A
S
V
R
S
S
G
Y
G
K
P
S
S
Site 74
Y515
A
S
V
R
S
S
G
Y
G
K
P
S
S
P
L
Site 75
S519
S
S
G
Y
G
K
P
S
S
P
L
K
M
F
S
Site 76
S520
S
G
Y
G
K
P
S
S
P
L
K
M
F
S
T
Site 77
S526
S
S
P
L
K
M
F
S
T
L
E
K
K
T
S
Site 78
T527
S
P
L
K
M
F
S
T
L
E
K
K
T
S
E
Site 79
S533
S
T
L
E
K
K
T
S
E
D
I
I
K
S
K
Site 80
S539
T
S
E
D
I
I
K
S
K
N
L
R
S
I
S
Site 81
S544
I
K
S
K
N
L
R
S
I
S
T
S
N
Q
P
Site 82
S546
S
K
N
L
R
S
I
S
T
S
N
Q
P
R
K
Site 83
S548
N
L
R
S
I
S
T
S
N
Q
P
R
K
K
E
Site 84
S558
P
R
K
K
E
I
L
S
G
T
K
L
I
K
P
Site 85
T575
L
D
K
P
A
H
K
T
E
S
C
L
S
T
R
Site 86
S577
K
P
A
H
K
T
E
S
C
L
S
T
R
K
K
Site 87
S580
H
K
T
E
S
C
L
S
T
R
K
K
S
E
N
Site 88
T581
K
T
E
S
C
L
S
T
R
K
K
S
E
N
P
Site 89
S585
C
L
S
T
R
K
K
S
E
N
P
T
E
T
D
Site 90
T589
R
K
K
S
E
N
P
T
E
T
D
S
C
I
Q
Site 91
S593
E
N
P
T
E
T
D
S
C
I
Q
F
Q
T
D
Site 92
T639
L
I
E
Q
I
K
A
T
F
S
E
K
E
K
E
Site 93
S641
E
Q
I
K
A
T
F
S
E
K
E
K
E
L
E
Site 94
Y670
F
K
L
N
Q
D
N
Y
I
L
Q
A
K
L
S
Site 95
S677
Y
I
L
Q
A
K
L
S
S
F
E
E
T
N
K
Site 96
S678
I
L
Q
A
K
L
S
S
F
E
E
T
N
K
K
Site 97
T682
K
L
S
S
F
E
E
T
N
K
K
Q
R
W
L
Site 98
T699
G
E
A
A
D
P
V
T
G
E
K
L
K
Q
I
Site 99
Y728
Q
Q
E
N
E
R
L
Y
N
Q
V
K
D
L
Q
Site 100
S751
R
M
F
K
E
N
Q
S
L
F
S
E
V
A
S
Site 101
S754
K
E
N
Q
S
L
F
S
E
V
A
S
L
K
E
Site 102
S758
S
L
F
S
E
V
A
S
L
K
E
Q
M
H
K
Site 103
S766
L
K
E
Q
M
H
K
S
R
F
L
S
Q
V
V
Site 104
S770
M
H
K
S
R
F
L
S
Q
V
V
E
D
S
E
Site 105
S776
L
S
Q
V
V
E
D
S
E
P
T
R
N
Q
N
Site 106
T785
P
T
R
N
Q
N
F
T
D
L
L
A
E
L
R
Site 107
Y835
Q
A
K
D
Q
I
A
Y
V
T
G
E
K
L
Y
Site 108
S900
I
E
K
L
K
A
E
S
G
N
P
S
I
R
Q
Site 109
S904
K
A
E
S
G
N
P
S
I
R
Q
K
I
R
L
Site 110
Y939
E
G
I
L
K
R
R
Y
P
N
S
L
P
A
L
Site 111
T956
A
A
S
A
A
G
D
T
V
D
K
N
T
V
E
Site 112
T961
G
D
T
V
D
K
N
T
V
E
F
M
E
K
R
Site 113
S986
K
D
E
D
A
K
K
S
L
R
T
M
E
Q
Q
Site 114
S1021
C
K
L
N
Q
H
D
S
P
R
I
K
A
L
E
Site 115
T1041
I
K
E
A
H
Q
I
T
V
R
N
L
E
A
E
Site 116
S1073
K
D
D
E
D
F
Q
S
I
E
F
Q
V
E
Q
Site 117
S1105
K
R
E
I
Q
D
L
S
K
T
V
E
R
L
Q
Site 118
T1107
E
I
Q
D
L
S
K
T
V
E
R
L
Q
K
D
Site 119
S1120
K
D
R
R
M
M
L
S
N
Q
N
S
K
G
R
Site 120
S1124
M
M
L
S
N
Q
N
S
K
G
R
E
E
M
S
Site 121
S1131
S
K
G
R
E
E
M
S
A
K
R
A
K
K
D
Site 122
S1143
K
K
D
V
L
H
S
S
K
G
N
A
N
S
F
Site 123
S1149
S
S
K
G
N
A
N
S
F
P
G
T
L
D
S
Site 124
T1153
N
A
N
S
F
P
G
T
L
D
S
K
L
Y
Q
Site 125
S1156
S
F
P
G
T
L
D
S
K
L
Y
Q
P
H
T
Site 126
Y1159
G
T
L
D
S
K
L
Y
Q
P
H
T
F
T
D
Site 127
T1163
S
K
L
Y
Q
P
H
T
F
T
D
S
H
V
S
Site 128
T1165
L
Y
Q
P
H
T
F
T
D
S
H
V
S
E
V
Site 129
S1167
Q
P
H
T
F
T
D
S
H
V
S
E
V
L
Q
Site 130
S1188
N
E
L
E
G
L
I
S
E
K
N
E
L
K
M
Site 131
S1197
K
N
E
L
K
M
K
S
E
A
V
M
N
Q
F
Site 132
T1215
M
R
R
V
K
E
D
T
A
A
H
I
A
S
L
Site 133
S1221
D
T
A
A
H
I
A
S
L
K
A
S
H
Q
R
Site 134
S1225
H
I
A
S
L
K
A
S
H
Q
R
E
I
E
K
Site 135
S1244
N
A
V
E
N
S
S
S
K
V
A
E
L
N
R
Site 136
T1255
E
L
N
R
K
I
A
T
Q
E
V
L
I
R
H
Site 137
S1265
V
L
I
R
H
F
Q
S
Q
V
N
E
L
Q
S
Site 138
S1272
S
Q
V
N
E
L
Q
S
K
Q
E
S
L
V
V
Site 139
S1276
E
L
Q
S
K
Q
E
S
L
V
V
S
E
V
R
Site 140
S1280
K
Q
E
S
L
V
V
S
E
V
R
E
E
I
L
Site 141
T1306
R
E
A
K
E
N
H
T
P
E
M
K
H
F
V
Site 142
T1371
R
E
L
E
K
F
R
T
E
L
D
S
I
L
D
Site 143
S1375
K
F
R
T
E
L
D
S
I
L
D
V
L
R
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation