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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
OGFRL1
Full Name:
Opioid growth factor receptor-like protein 1
Alias:
Type:
Mass (Da):
51252
Number AA:
451
UniProt ID:
Q5TC84
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T14
G
V
S
F
R
E
P
T
T
V
E
D
C
D
S
Site 2
T15
V
S
F
R
E
P
T
T
V
E
D
C
D
S
T
Site 3
S21
T
T
V
E
D
C
D
S
T
W
Q
T
D
S
E
Site 4
T22
T
V
E
D
C
D
S
T
W
Q
T
D
S
E
P
Site 5
T25
D
C
D
S
T
W
Q
T
D
S
E
P
E
P
E
Site 6
S27
D
S
T
W
Q
T
D
S
E
P
E
P
E
E
P
Site 7
S40
E
P
G
P
G
G
G
S
E
G
P
G
Q
E
S
Site 8
S64
A
G
G
R
P
G
A
S
P
A
P
D
E
D
A
Site 9
T86
G
G
D
S
T
E
A
T
A
K
P
K
R
S
F
Site 10
S92
A
T
A
K
P
K
R
S
F
Y
A
A
R
D
L
Site 11
Y94
A
K
P
K
R
S
F
Y
A
A
R
D
L
Y
K
Site 12
Y100
F
Y
A
A
R
D
L
Y
K
Y
R
H
Q
Y
P
Site 13
Y102
A
A
R
D
L
Y
K
Y
R
H
Q
Y
P
N
F
Site 14
Y106
L
Y
K
Y
R
H
Q
Y
P
N
F
K
D
I
R
Site 15
Y114
P
N
F
K
D
I
R
Y
Q
N
D
L
S
N
L
Site 16
Y124
D
L
S
N
L
R
F
Y
K
N
K
I
P
F
K
Site 17
Y136
P
F
K
P
D
G
V
Y
I
E
E
V
L
S
K
Site 18
Y148
L
S
K
W
K
G
D
Y
E
K
L
E
H
N
H
Site 19
Y179
Y
A
K
E
L
T
T
Y
E
I
E
E
F
K
K
Site 20
T187
E
I
E
E
F
K
K
T
K
E
A
I
R
R
F
Site 21
T213
G
I
K
L
T
D
K
T
G
N
V
A
R
A
V
Site 22
Y236
L
N
E
S
Q
H
N
Y
L
R
I
T
R
I
L
Site 23
T240
Q
H
N
Y
L
R
I
T
R
I
L
K
S
L
G
Site 24
S245
R
I
T
R
I
L
K
S
L
G
E
L
G
Y
E
Site 25
Y251
K
S
L
G
E
L
G
Y
E
S
F
K
S
P
L
Site 26
S253
L
G
E
L
G
Y
E
S
F
K
S
P
L
V
K
Site 27
Y282
I
K
Q
S
A
L
E
Y
F
V
Y
T
I
R
D
Site 28
Y285
S
A
L
E
Y
F
V
Y
T
I
R
D
R
R
E
Site 29
T286
A
L
E
Y
F
V
Y
T
I
R
D
R
R
E
R
Site 30
T305
R
F
A
Q
K
H
Y
T
P
S
E
N
F
I
W
Site 31
S320
G
P
P
R
K
E
Q
S
E
G
S
K
A
Q
K
Site 32
S323
R
K
E
Q
S
E
G
S
K
A
Q
K
M
S
S
Site 33
S329
G
S
K
A
Q
K
M
S
S
P
L
A
S
S
H
Site 34
S330
S
K
A
Q
K
M
S
S
P
L
A
S
S
H
N
Site 35
S334
K
M
S
S
P
L
A
S
S
H
N
S
Q
T
S
Site 36
S335
M
S
S
P
L
A
S
S
H
N
S
Q
T
S
M
Site 37
S338
P
L
A
S
S
H
N
S
Q
T
S
M
H
K
K
Site 38
T340
A
S
S
H
N
S
Q
T
S
M
H
K
K
A
K
Site 39
S341
S
S
H
N
S
Q
T
S
M
H
K
K
A
K
D
Site 40
S349
M
H
K
K
A
K
D
S
K
N
S
S
S
A
V
Site 41
S352
K
A
K
D
S
K
N
S
S
S
A
V
H
L
N
Site 42
S353
A
K
D
S
K
N
S
S
S
A
V
H
L
N
S
Site 43
S354
K
D
S
K
N
S
S
S
A
V
H
L
N
S
K
Site 44
S360
S
S
A
V
H
L
N
S
K
T
A
E
D
K
K
Site 45
T377
P
K
E
P
V
E
E
T
D
R
P
S
P
E
P
Site 46
S381
V
E
E
T
D
R
P
S
P
E
P
S
N
E
A
Site 47
S385
D
R
P
S
P
E
P
S
N
E
A
A
K
P
R
Site 48
T394
E
A
A
K
P
R
N
T
E
K
D
S
N
A
E
Site 49
S398
P
R
N
T
E
K
D
S
N
A
E
N
M
N
S
Site 50
S405
S
N
A
E
N
M
N
S
Q
P
E
K
T
V
T
Site 51
T410
M
N
S
Q
P
E
K
T
V
T
T
P
T
E
K
Site 52
T412
S
Q
P
E
K
T
V
T
T
P
T
E
K
K
E
Site 53
T413
Q
P
E
K
T
V
T
T
P
T
E
K
K
E
S
Site 54
S420
T
P
T
E
K
K
E
S
V
S
P
E
N
N
E
Site 55
S422
T
E
K
K
E
S
V
S
P
E
N
N
E
E
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation