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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CYP4A22
Full Name:
Cytochrome P450 4A22
Alias:
CYPIVA22;Fatty acid omega-hydroxylase;Lauric acid omega-hydroxylase
Type:
Mass (Da):
59246
Number AA:
519
UniProt ID:
Q5TCH4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
V
S
V
L
S
P
S
Site 2
S4
_
_
_
_
M
S
V
S
V
L
S
P
S
R
R
Site 3
S7
_
M
S
V
S
V
L
S
P
S
R
R
L
G
G
Site 4
S9
S
V
S
V
L
S
P
S
R
R
L
G
G
V
S
Site 5
T81
R
I
Q
E
R
V
K
T
F
P
S
A
C
P
Y
Site 6
Y100
G
K
V
R
V
Q
L
Y
D
P
D
Y
M
K
V
Site 7
Y104
V
Q
L
Y
D
P
D
Y
M
K
V
I
L
G
R
Site 8
S112
M
K
V
I
L
G
R
S
D
P
K
S
H
G
S
Site 9
S116
L
G
R
S
D
P
K
S
H
G
S
Y
K
F
L
Site 10
Y120
D
P
K
S
H
G
S
Y
K
F
L
A
P
R
I
Site 11
T147
F
Q
H
R
R
M
L
T
P
A
F
H
N
D
I
Site 12
Y158
H
N
D
I
L
K
P
Y
V
G
L
M
A
D
S
Site 13
S181
E
E
L
L
G
Q
D
S
P
L
E
V
F
Q
H
Site 14
S200
T
L
D
T
I
M
K
S
A
F
S
H
Q
G
S
Site 15
S207
S
A
F
S
H
Q
G
S
I
Q
V
D
R
N
S
Site 16
S214
S
I
Q
V
D
R
N
S
Q
S
Y
I
Q
A
I
Site 17
Y217
V
D
R
N
S
Q
S
Y
I
Q
A
I
S
D
L
Site 18
T241
N
A
F
H
E
N
D
T
I
Y
S
L
T
S
A
Site 19
Y243
F
H
E
N
D
T
I
Y
S
L
T
S
A
G
R
Site 20
S244
H
E
N
D
T
I
Y
S
L
T
S
A
G
R
W
Site 21
S247
D
T
I
Y
S
L
T
S
A
G
R
W
T
H
R
Site 22
T252
L
T
S
A
G
R
W
T
H
R
A
C
Q
L
A
Site 23
T317
D
L
R
A
E
V
D
T
F
M
F
E
G
H
D
Site 24
S328
E
G
H
D
T
T
A
S
G
I
S
W
I
L
Y
Site 25
S360
G
L
L
G
D
G
A
S
I
T
W
N
H
L
D
Site 26
S394
P
G
I
G
R
E
L
S
T
P
V
T
F
P
D
Site 27
T395
G
I
G
R
E
L
S
T
P
V
T
F
P
D
G
Site 28
T398
R
E
L
S
T
P
V
T
F
P
D
G
R
S
L
Site 29
S440
P
S
R
F
A
P
G
S
A
Q
H
S
H
A
F
Site 30
S444
A
P
G
S
A
Q
H
S
H
A
F
L
P
F
S
Site 31
S451
S
H
A
F
L
P
F
S
G
G
S
R
N
C
I
Site 32
S498
M
A
R
L
V
L
K
S
K
N
G
I
H
L
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation