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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AKD1
Full Name:
Adenylate kinase domain-containing protein 1
Alias:
adenylate kinase domain containing 1; AKD2; C6orf199; C6orf224; CF199; coiled-coil domain-containing protein C6orf199; dJ70A9.1; FLJ25791; FLJ30976; FLJ42177; MGC26954
Type:
Kinase (non-protein); EC 2.7.4.3
Mass (Da):
86640
Number AA:
UniProt ID:
Q5TCS8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0019205
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
T
S
Q
E
K
T
E
E
Y
P
F
A
D
Site 2
Y10
S
Q
E
K
T
E
E
Y
P
F
A
D
I
F
D
Site 3
T21
D
I
F
D
E
D
E
T
E
R
N
F
L
L
S
Site 4
T45
K
P
G
V
G
K
T
T
L
A
R
Y
I
T
Q
Site 5
S85
M
L
Q
S
M
L
I
S
G
Q
S
I
P
D
E
Site 6
Y152
I
N
I
K
C
P
D
Y
D
L
C
Q
R
I
S
Site 7
T167
G
Q
R
Q
H
N
N
T
G
Y
I
Y
S
R
D
Site 8
Y169
R
Q
H
N
N
T
G
Y
I
Y
S
R
D
Q
W
Site 9
Y171
H
N
N
T
G
Y
I
Y
S
R
D
Q
W
D
P
Site 10
Y233
L
V
Q
R
P
E
D
Y
L
E
N
V
E
N
I
Site 11
Y263
M
A
E
H
N
P
Q
Y
L
I
E
L
N
G
N
Site 12
Y286
I
V
M
D
R
L
K
Y
L
N
L
K
R
A
A
Site 13
T296
L
K
R
A
A
I
L
T
K
L
Q
G
A
E
E
Site 14
T308
A
E
E
E
I
N
D
T
M
E
N
D
E
L
F
Site 15
T317
E
N
D
E
L
F
R
T
L
A
S
Y
K
L
I
Site 16
Y328
Y
K
L
I
A
P
R
Y
R
W
Q
R
S
K
W
Site 17
S350
L
K
D
G
N
I
Y
S
G
L
P
D
Y
S
V
Site 18
S367
L
G
K
I
Y
C
L
S
S
E
E
A
L
K
P
Site 19
S368
G
K
I
Y
C
L
S
S
E
E
A
L
K
P
F
Site 20
S402
F
I
L
G
P
Q
Y
S
G
K
T
T
L
C
N
Site 21
T406
P
Q
Y
S
G
K
T
T
L
C
N
M
L
A
E
Site 22
Y415
C
N
M
L
A
E
N
Y
K
G
K
V
V
D
Y
Site 23
Y422
Y
K
G
K
V
V
D
Y
A
Q
L
V
Q
P
R
Site 24
T436
R
F
D
K
A
R
E
T
L
V
E
N
T
I
A
Site 25
T469
Q
A
R
K
Q
A
E
T
A
L
R
E
F
Q
R
Site 26
Y478
L
R
E
F
Q
R
Q
Y
E
K
M
E
F
G
V
Site 27
S493
F
P
M
E
A
T
H
S
S
I
D
E
E
G
Y
Site 28
S494
P
M
E
A
T
H
S
S
I
D
E
E
G
Y
I
Site 29
Y500
S
S
I
D
E
E
G
Y
I
Q
G
S
Q
R
D
Site 30
S504
E
E
G
Y
I
Q
G
S
Q
R
D
R
G
S
S
Site 31
S510
G
S
Q
R
D
R
G
S
S
L
V
D
T
E
E
Site 32
S511
S
Q
R
D
R
G
S
S
L
V
D
T
E
E
A
Site 33
T515
R
G
S
S
L
V
D
T
E
E
A
K
T
K
S
Site 34
T520
V
D
T
E
E
A
K
T
K
S
E
N
V
L
H
Site 35
T544
D
G
K
E
T
G
E
T
F
T
F
K
R
H
S
Site 36
T546
K
E
T
G
E
T
F
T
F
K
R
H
S
Q
D
Site 37
S551
T
F
T
F
K
R
H
S
Q
D
A
S
Q
D
V
Site 38
S555
K
R
H
S
Q
D
A
S
Q
D
V
K
L
Y
S
Site 39
S562
S
Q
D
V
K
L
Y
S
D
T
A
P
T
E
D
Site 40
Y601
D
I
N
F
E
Q
P
Y
E
K
H
A
E
I
L
Site 41
Y629
R
F
P
G
A
P
K
Y
G
G
W
I
V
D
N
Site 42
S661
P
D
L
V
I
Y
L
S
D
T
E
N
N
G
K
Site 43
Y675
K
C
L
F
N
R
I
Y
L
Q
K
K
S
E
I
Site 44
S680
R
I
Y
L
Q
K
K
S
E
I
D
S
K
I
L
Site 45
S684
Q
K
K
S
E
I
D
S
K
I
L
E
R
L
L
Site 46
S704
K
K
K
E
E
E
K
S
H
R
R
G
I
E
T
Site 47
T711
S
H
R
R
G
I
E
T
R
R
R
K
S
K
A
Site 48
S716
I
E
T
R
R
R
K
S
K
A
T
G
T
Y
E
Site 49
T719
R
R
R
K
S
K
A
T
G
T
Y
E
S
E
G
Site 50
T721
R
K
S
K
A
T
G
T
Y
E
S
E
G
K
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation