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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RSPH4A
Full Name:
Radial spoke head protein 4 homolog A
Alias:
Radial spoke head-like protein 3
Type:
Mass (Da):
80733
Number AA:
716
UniProt ID:
Q5TD94
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
E
D
S
T
S
P
K
Q
E
K
E
N
Site 2
T20
N
Q
E
E
L
G
E
T
R
R
P
W
E
G
K
Site 3
T28
R
R
P
W
E
G
K
T
A
A
S
P
Q
Y
S
Site 4
S31
W
E
G
K
T
A
A
S
P
Q
Y
S
E
P
E
Site 5
Y34
K
T
A
A
S
P
Q
Y
S
E
P
E
S
S
E
Site 6
S35
T
A
A
S
P
Q
Y
S
E
P
E
S
S
E
P
Site 7
S39
P
Q
Y
S
E
P
E
S
S
E
P
L
E
A
K
Site 8
S40
Q
Y
S
E
P
E
S
S
E
P
L
E
A
K
Q
Site 9
T51
E
A
K
Q
G
P
E
T
G
R
Q
S
R
S
S
Site 10
S55
G
P
E
T
G
R
Q
S
R
S
S
R
P
W
S
Site 11
S57
E
T
G
R
Q
S
R
S
S
R
P
W
S
P
Q
Site 12
S58
T
G
R
Q
S
R
S
S
R
P
W
S
P
Q
S
Site 13
S62
S
R
S
S
R
P
W
S
P
Q
S
R
A
K
T
Site 14
S65
S
R
P
W
S
P
Q
S
R
A
K
T
P
L
G
Site 15
T69
S
P
Q
S
R
A
K
T
P
L
G
G
P
A
G
Site 16
T79
G
G
P
A
G
P
E
T
S
S
P
A
P
V
S
Site 17
S81
P
A
G
P
E
T
S
S
P
A
P
V
S
P
R
Site 18
S86
T
S
S
P
A
P
V
S
P
R
E
P
S
S
S
Site 19
S91
P
V
S
P
R
E
P
S
S
S
P
S
P
L
A
Site 20
S92
V
S
P
R
E
P
S
S
S
P
S
P
L
A
P
Site 21
S93
S
P
R
E
P
S
S
S
P
S
P
L
A
P
A
Site 22
S95
R
E
P
S
S
S
P
S
P
L
A
P
A
R
Q
Site 23
S110
D
L
A
A
P
P
Q
S
D
R
T
T
S
V
I
Site 24
T113
A
P
P
Q
S
D
R
T
T
S
V
I
P
E
A
Site 25
T114
P
P
Q
S
D
R
T
T
S
V
I
P
E
A
G
Site 26
S115
P
Q
S
D
R
T
T
S
V
I
P
E
A
G
T
Site 27
T122
S
V
I
P
E
A
G
T
P
Y
P
D
P
L
E
Site 28
Y124
I
P
E
A
G
T
P
Y
P
D
P
L
E
Q
S
Site 29
S132
P
D
P
L
E
Q
S
S
D
K
R
E
S
T
P
Site 30
S137
Q
S
S
D
K
R
E
S
T
P
H
H
T
S
Q
Site 31
T138
S
S
D
K
R
E
S
T
P
H
H
T
S
Q
S
Site 32
S143
E
S
T
P
H
H
T
S
Q
S
E
G
N
T
F
Site 33
S145
T
P
H
H
T
S
Q
S
E
G
N
T
F
Q
Q
Site 34
T149
T
S
Q
S
E
G
N
T
F
Q
Q
S
Q
Q
P
Site 35
S153
E
G
N
T
F
Q
Q
S
Q
Q
P
K
P
H
L
Site 36
S167
L
C
G
R
R
D
V
S
Y
N
N
A
K
Q
K
Site 37
Y168
C
G
R
R
D
V
S
Y
N
N
A
K
Q
K
E
Site 38
S186
D
V
F
Q
E
E
D
S
N
S
D
Y
D
L
Q
Site 39
S188
F
Q
E
E
D
S
N
S
D
Y
D
L
Q
Q
P
Site 40
Y190
E
E
D
S
N
S
D
Y
D
L
Q
Q
P
A
P
Site 41
S200
Q
Q
P
A
P
G
G
S
E
V
A
P
S
M
L
Site 42
Y217
T
I
Q
N
A
K
A
Y
L
L
K
T
S
S
N
Site 43
T221
A
K
A
Y
L
L
K
T
S
S
N
S
G
F
N
Site 44
S223
A
Y
L
L
K
T
S
S
N
S
G
F
N
L
Y
Site 45
Y230
S
N
S
G
F
N
L
Y
D
H
L
S
N
M
L
Site 46
T238
D
H
L
S
N
M
L
T
K
I
L
N
E
R
P
Site 47
T280
N
E
N
E
L
L
P
T
Y
E
I
A
E
K
Q
Site 48
Y281
E
N
E
L
L
P
T
Y
E
I
A
E
K
Q
K
Site 49
T347
A
L
K
Q
L
T
D
T
H
P
I
Q
R
C
R
Site 50
S396
E
E
R
D
N
G
E
S
E
A
H
E
D
E
E
Site 51
S409
E
E
D
E
L
P
K
S
F
Y
K
A
P
Q
A
Site 52
Y411
D
E
L
P
K
S
F
Y
K
A
P
Q
A
I
P
Site 53
T424
I
P
K
E
E
S
R
T
G
A
N
K
Y
V
Y
Site 54
Y429
S
R
T
G
A
N
K
Y
V
Y
F
V
C
N
E
Site 55
Y431
T
G
A
N
K
Y
V
Y
F
V
C
N
E
P
G
Site 56
S472
R
L
D
A
P
I
I
S
Y
P
P
F
P
G
N
Site 57
Y473
L
D
A
P
I
I
S
Y
P
P
F
P
G
N
E
Site 58
Y483
F
P
G
N
E
S
N
Y
L
R
A
Q
I
A
R
Site 59
S492
R
A
Q
I
A
R
I
S
A
G
T
H
V
S
P
Site 60
S522
E
A
E
G
G
R
N
S
F
E
E
N
P
D
F
Site 61
S580
E
D
E
E
K
D
D
S
D
Y
I
E
Q
E
V
Site 62
Y582
E
E
K
D
D
S
D
Y
I
E
Q
E
V
G
L
Site 63
T608
I
Q
N
I
P
P
W
T
T
R
L
S
S
N
L
Site 64
S612
P
P
W
T
T
R
L
S
S
N
L
I
P
Q
Y
Site 65
S613
P
W
T
T
R
L
S
S
N
L
I
P
Q
Y
A
Site 66
Y633
S
N
L
W
P
G
A
Y
A
F
S
N
G
K
K
Site 67
Y645
G
K
K
F
E
N
F
Y
I
G
W
G
H
K
Y
Site 68
Y652
Y
I
G
W
G
H
K
Y
S
P
D
N
Y
T
P
Site 69
Y657
H
K
Y
S
P
D
N
Y
T
P
P
V
P
P
P
Site 70
T658
K
Y
S
P
D
N
Y
T
P
P
V
P
P
P
V
Site 71
Y666
P
P
V
P
P
P
V
Y
Q
E
Y
P
S
G
P
Site 72
Y669
P
P
P
V
Y
Q
E
Y
P
S
G
P
E
I
T
Site 73
S671
P
V
Y
Q
E
Y
P
S
G
P
E
I
T
E
M
Site 74
S682
I
T
E
M
D
D
P
S
V
E
E
E
Q
A
F
Site 75
S705
L
A
A
E
N
E
E
S
E
E
D
E
D
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation