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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C6orf174
Full Name:
Uncharacterized protein C6orf174
Alias:
CF174; chromosome 6 open reading frame 174; dJ403A15.3; LOC387104
Type:
Unknown function
Mass (Da):
103181
Number AA:
947
UniProt ID:
Q5TF21
International Prot ID:
IPI00647205
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016020
GO:0016021
GO:0031224
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
Q
P
P
I
G
G
A
Site 2
T13
I
G
G
A
A
P
A
T
A
A
A
S
P
A
A
Site 3
S32
A
R
L
H
P
E
G
S
S
R
K
Q
Q
R
A
Site 4
S41
R
K
Q
Q
R
A
Q
S
P
A
R
P
R
D
S
Site 5
S48
S
P
A
R
P
R
D
S
S
L
R
Q
T
I
A
Site 6
S49
P
A
R
P
R
D
S
S
L
R
Q
T
I
A
A
Site 7
T53
R
D
S
S
L
R
Q
T
I
A
A
T
R
S
P
Site 8
T57
L
R
Q
T
I
A
A
T
R
S
P
V
G
A
G
Site 9
S59
Q
T
I
A
A
T
R
S
P
V
G
A
G
T
K
Site 10
T65
R
S
P
V
G
A
G
T
K
L
N
S
V
R
Q
Site 11
S69
G
A
G
T
K
L
N
S
V
R
Q
Q
Q
L
Q
Site 12
T85
Q
Q
Q
Q
G
N
K
T
G
S
R
T
G
P
P
Site 13
S87
Q
Q
G
N
K
T
G
S
R
T
G
P
P
A
S
Site 14
T89
G
N
K
T
G
S
R
T
G
P
P
A
S
I
R
Site 15
S94
S
R
T
G
P
P
A
S
I
R
G
G
G
G
G
Site 16
T106
G
G
G
A
E
K
A
T
P
L
A
P
K
G
A
Site 17
S152
E
P
P
R
E
L
E
S
V
P
S
K
L
G
E
Site 18
S155
R
E
L
E
S
V
P
S
K
L
G
E
P
P
P
Site 19
S180
G
G
G
A
G
G
G
S
G
E
R
E
G
G
A
Site 20
S209
R
A
Q
Q
R
G
G
S
G
G
E
G
A
S
P
Site 21
S215
G
S
G
G
E
G
A
S
P
S
P
S
S
S
S
Site 22
S217
G
G
E
G
A
S
P
S
P
S
S
S
S
A
G
Site 23
S219
E
G
A
S
P
S
P
S
S
S
S
A
G
K
T
Site 24
S220
G
A
S
P
S
P
S
S
S
S
A
G
K
T
P
Site 25
S221
A
S
P
S
P
S
S
S
S
A
G
K
T
P
G
Site 26
S222
S
P
S
P
S
S
S
S
A
G
K
T
P
G
T
Site 27
T226
S
S
S
S
A
G
K
T
P
G
T
G
S
R
N
Site 28
T229
S
A
G
K
T
P
G
T
G
S
R
N
S
G
S
Site 29
S231
G
K
T
P
G
T
G
S
R
N
S
G
S
G
V
Site 30
S234
P
G
T
G
S
R
N
S
G
S
G
V
A
G
G
Site 31
S236
T
G
S
R
N
S
G
S
G
V
A
G
G
G
S
Site 32
S243
S
G
V
A
G
G
G
S
G
G
G
G
S
Y
W
Site 33
S248
G
G
S
G
G
G
G
S
Y
W
K
E
G
C
L
Site 34
Y249
G
S
G
G
G
G
S
Y
W
K
E
G
C
L
Q
Site 35
S286
H
A
K
N
G
G
G
S
S
S
R
S
S
P
V
Site 36
S287
A
K
N
G
G
G
S
S
S
R
S
S
P
V
S
Site 37
S288
K
N
G
G
G
S
S
S
R
S
S
P
V
S
G
Site 38
S290
G
G
G
S
S
S
R
S
S
P
V
S
G
P
P
Site 39
S291
G
G
S
S
S
R
S
S
P
V
S
G
P
P
A
Site 40
S294
S
S
R
S
S
P
V
S
G
P
P
A
V
C
E
Site 41
S321
A
A
E
G
P
Q
Q
S
A
E
G
S
A
S
G
Site 42
S325
P
Q
Q
S
A
E
G
S
A
S
G
G
G
M
Q
Site 43
S327
Q
S
A
E
G
S
A
S
G
G
G
M
Q
A
A
Site 44
S338
M
Q
A
A
A
P
P
S
S
Q
P
H
P
Q
Q
Site 45
S339
Q
A
A
A
P
P
S
S
Q
P
H
P
Q
Q
L
Site 46
T365
K
L
R
E
E
N
E
T
L
K
N
E
I
D
E
Site 47
T383
E
M
D
E
M
R
D
T
F
F
E
E
D
A
C
Site 48
Y423
A
E
R
K
R
L
R
Y
A
Q
T
G
E
I
D
Site 49
S436
I
D
G
E
L
L
R
S
L
E
Q
D
L
K
V
Site 50
S448
L
K
V
A
K
D
V
S
V
R
L
H
H
E
L
Site 51
T464
N
V
E
E
K
R
T
T
T
E
D
E
N
E
K
Site 52
T465
V
E
E
K
R
T
T
T
E
D
E
N
E
K
L
Site 53
S497
L
E
K
M
K
E
L
S
L
K
R
R
G
S
K
Site 54
S503
L
S
L
K
R
R
G
S
K
D
L
P
K
S
E
Site 55
S509
G
S
K
D
L
P
K
S
E
K
K
A
Q
Q
T
Site 56
T516
S
E
K
K
A
Q
Q
T
P
T
E
E
D
N
E
Site 57
Y560
F
E
H
E
L
Q
K
Y
R
S
F
Y
G
D
L
Site 58
S562
H
E
L
Q
K
Y
R
S
F
Y
G
D
L
D
S
Site 59
Y564
L
Q
K
Y
R
S
F
Y
G
D
L
D
S
P
L
Site 60
S569
S
F
Y
G
D
L
D
S
P
L
P
K
G
E
A
Site 61
S581
G
E
A
G
G
P
P
S
T
R
E
A
E
L
K
Site 62
S630
R
G
D
D
F
N
G
S
A
N
P
L
M
R
E
Site 63
S639
N
P
L
M
R
E
Q
S
E
S
L
S
E
L
R
Site 64
S641
L
M
R
E
Q
S
E
S
L
S
E
L
R
Q
H
Site 65
S643
R
E
Q
S
E
S
L
S
E
L
R
Q
H
L
Q
Site 66
T656
L
Q
L
V
E
D
E
T
E
L
L
R
R
N
V
Site 67
T674
E
E
Q
N
K
R
I
T
A
E
L
N
K
Y
K
Site 68
Y680
I
T
A
E
L
N
K
Y
K
Y
K
S
G
G
H
Site 69
Y682
A
E
L
N
K
Y
K
Y
K
S
G
G
H
D
S
Site 70
S684
L
N
K
Y
K
Y
K
S
G
G
H
D
S
A
R
Site 71
S689
Y
K
S
G
G
H
D
S
A
R
H
H
D
N
A
Site 72
Y724
G
K
V
M
Q
L
Q
Y
E
N
R
V
L
M
S
Site 73
Y736
L
M
S
N
M
Q
R
Y
D
L
A
S
H
L
G
Site 74
S740
M
Q
R
Y
D
L
A
S
H
L
G
I
R
G
S
Site 75
S747
S
H
L
G
I
R
G
S
P
R
D
S
D
A
E
Site 76
S751
I
R
G
S
P
R
D
S
D
A
E
S
D
A
G
Site 77
S755
P
R
D
S
D
A
E
S
D
A
G
K
K
E
S
Site 78
S762
S
D
A
G
K
K
E
S
D
D
D
S
R
P
P
Site 79
S766
K
K
E
S
D
D
D
S
R
P
P
H
R
K
R
Site 80
S781
E
G
P
I
G
G
E
S
D
S
E
E
V
R
N
Site 81
S783
P
I
G
G
E
S
D
S
E
E
V
R
N
I
R
Site 82
T793
V
R
N
I
R
C
L
T
P
T
R
S
F
Y
P
Site 83
T795
N
I
R
C
L
T
P
T
R
S
F
Y
P
A
P
Site 84
S797
R
C
L
T
P
T
R
S
F
Y
P
A
P
G
P
Site 85
Y799
L
T
P
T
R
S
F
Y
P
A
P
G
P
W
P
Site 86
S808
A
P
G
P
W
P
K
S
F
S
D
R
Q
Q
M
Site 87
S810
G
P
W
P
K
S
F
S
D
R
Q
Q
M
K
D
Site 88
S820
Q
Q
M
K
D
I
R
S
E
A
E
R
L
G
K
Site 89
T828
E
A
E
R
L
G
K
T
I
D
R
L
I
A
D
Site 90
S837
D
R
L
I
A
D
T
S
T
I
I
T
E
A
R
Site 91
S863
M
D
E
E
D
D
G
S
R
I
R
E
H
E
L
Site 92
Y872
I
R
E
H
E
L
L
Y
R
I
N
A
Q
M
K
Site 93
T887
A
F
R
K
E
L
Q
T
F
I
D
R
L
E
V
Site 94
S897
D
R
L
E
V
P
K
S
A
D
D
R
G
A
E
Site 95
S908
R
G
A
E
E
P
I
S
V
S
Q
M
F
Q
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation