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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NT5DC1
Full Name:
5'-nucleotidase domain-containing protein 1
Alias:
Type:
Mass (Da):
51845
Number AA:
455
UniProt ID:
Q5TFE4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T20
V
G
F
D
L
D
H
T
L
C
R
Y
N
L
P
Site 2
Y24
L
D
H
T
L
C
R
Y
N
L
P
E
S
A
P
Site 3
S29
C
R
Y
N
L
P
E
S
A
P
L
I
Y
N
S
Site 4
T55
D
K
E
L
L
N
V
T
P
E
D
W
D
F
C
Site 5
T83
L
K
L
A
N
N
G
T
V
L
R
A
S
H
G
Site 6
S88
N
G
T
V
L
R
A
S
H
G
T
K
M
M
T
Site 7
T91
V
L
R
A
S
H
G
T
K
M
M
T
P
E
V
Site 8
T95
S
H
G
T
K
M
M
T
P
E
V
L
A
E
A
Site 9
T115
W
K
H
F
L
S
D
T
G
M
A
C
R
S
G
Site 10
Y125
A
C
R
S
G
K
Y
Y
F
Y
D
N
Y
F
D
Site 11
Y127
R
S
G
K
Y
Y
F
Y
D
N
Y
F
D
L
P
Site 12
Y130
K
Y
Y
F
Y
D
N
Y
F
D
L
P
G
A
L
Site 13
Y145
L
C
A
R
V
V
D
Y
L
T
K
L
N
N
G
Site 14
T147
A
R
V
V
D
Y
L
T
K
L
N
N
G
Q
K
Site 15
Y182
F
K
E
N
C
G
I
Y
F
P
E
I
K
R
D
Site 16
Y193
I
K
R
D
P
G
R
Y
L
H
S
C
P
E
S
Site 17
S196
D
P
G
R
Y
L
H
S
C
P
E
S
V
K
K
Site 18
Y225
I
T
S
S
H
S
D
Y
C
R
L
L
C
E
Y
Site 19
S256
A
L
K
P
G
F
F
S
H
L
P
S
Q
R
P
Site 20
S260
G
F
F
S
H
L
P
S
Q
R
P
F
R
T
L
Site 21
S278
E
E
Q
E
A
L
P
S
L
D
K
P
G
W
Y
Site 22
S286
L
D
K
P
G
W
Y
S
Q
G
N
A
V
H
L
Site 23
Y294
Q
G
N
A
V
H
L
Y
E
L
L
K
K
M
T
Site 24
T301
Y
E
L
L
K
K
M
T
G
K
P
E
P
K
V
Site 25
Y310
K
P
E
P
K
V
V
Y
F
G
D
S
M
H
S
Site 26
Y325
D
I
F
P
A
R
H
Y
S
N
W
E
T
V
L
Site 27
T330
R
H
Y
S
N
W
E
T
V
L
I
L
E
E
L
Site 28
T343
E
L
R
G
D
E
G
T
R
S
Q
R
P
E
E
Site 29
S345
R
G
D
E
G
T
R
S
Q
R
P
E
E
S
E
Site 30
S351
R
S
Q
R
P
E
E
S
E
P
L
E
K
K
G
Site 31
Y360
P
L
E
K
K
G
K
Y
E
G
P
K
A
K
P
Site 32
S372
A
K
P
L
N
T
S
S
K
K
W
G
S
F
F
Site 33
S377
T
S
S
K
K
W
G
S
F
F
I
D
S
V
L
Site 34
T389
S
V
L
G
L
E
N
T
E
D
S
L
V
Y
T
Site 35
S392
G
L
E
N
T
E
D
S
L
V
Y
T
W
S
C
Site 36
T396
T
E
D
S
L
V
Y
T
W
S
C
K
R
I
S
Site 37
T404
W
S
C
K
R
I
S
T
Y
S
T
I
A
I
P
Site 38
T407
K
R
I
S
T
Y
S
T
I
A
I
P
S
I
E
Site 39
Y423
I
A
E
L
P
L
D
Y
K
F
T
R
F
S
S
Site 40
T426
L
P
L
D
Y
K
F
T
R
F
S
S
S
N
S
Site 41
S429
D
Y
K
F
T
R
F
S
S
S
N
S
K
T
A
Site 42
S430
Y
K
F
T
R
F
S
S
S
N
S
K
T
A
G
Site 43
S431
K
F
T
R
F
S
S
S
N
S
K
T
A
G
Y
Site 44
S433
T
R
F
S
S
S
N
S
K
T
A
G
Y
Y
P
Site 45
T435
F
S
S
S
N
S
K
T
A
G
Y
Y
P
N
P
Site 46
Y438
S
N
S
K
T
A
G
Y
Y
P
N
P
P
L
V
Site 47
Y439
N
S
K
T
A
G
Y
Y
P
N
P
P
L
V
L
Site 48
S447
P
N
P
P
L
V
L
S
S
D
E
T
L
I
S
Site 49
S448
N
P
P
L
V
L
S
S
D
E
T
L
I
S
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation