KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
AHDC1
Full Name:
AT-hook DNA-binding motif-containing protein 1
Alias:
AT hook, DNA binding motif, containing 1; CL23945; DJ159A19.3; RP1-159A19.1
Type:
DNA binding protein
Mass (Da):
168349
Number AA:
1603
UniProt ID:
Q5TGY3
International Prot ID:
IPI00397015
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
V
T
S
S
A
V
C
S
S
P
D
Y
L
R
E
Site 2
S18
T
S
S
A
V
C
S
S
P
D
Y
L
R
E
P
Site 3
Y21
A
V
C
S
S
P
D
Y
L
R
E
P
K
Y
Y
Site 4
Y27
D
Y
L
R
E
P
K
Y
Y
P
G
G
P
P
T
Site 5
Y28
Y
L
R
E
P
K
Y
Y
P
G
G
P
P
T
P
Site 6
T34
Y
Y
P
G
G
P
P
T
P
R
P
L
L
P
T
Site 7
T41
T
P
R
P
L
L
P
T
R
P
P
A
S
P
P
Site 8
S46
L
P
T
R
P
P
A
S
P
P
D
K
A
F
S
Site 9
S53
S
P
P
D
K
A
F
S
T
H
A
F
S
E
N
Site 10
T54
P
P
D
K
A
F
S
T
H
A
F
S
E
N
P
Site 11
S58
A
F
S
T
H
A
F
S
E
N
P
R
P
P
P
Site 12
S70
P
P
P
R
R
D
P
S
T
R
R
P
P
V
L
Site 13
T71
P
P
R
R
D
P
S
T
R
R
P
P
V
L
A
Site 14
S93
P
R
A
A
R
P
V
S
Q
A
R
C
P
T
P
Site 15
T99
V
S
Q
A
R
C
P
T
P
V
G
D
G
S
S
Site 16
S105
P
T
P
V
G
D
G
S
S
S
R
R
C
W
D
Site 17
S106
T
P
V
G
D
G
S
S
S
R
R
C
W
D
N
Site 18
S107
P
V
G
D
G
S
S
S
R
R
C
W
D
N
G
Site 19
T132
I
D
I
M
K
D
L
T
R
L
S
Q
D
L
Q
Site 20
S135
M
K
D
L
T
R
L
S
Q
D
L
Q
H
S
G
Site 21
S141
L
S
Q
D
L
Q
H
S
G
V
H
L
D
C
G
Site 22
S153
D
C
G
G
L
R
L
S
R
P
P
A
P
P
P
Site 23
Y165
P
P
P
G
D
L
Q
Y
S
F
F
S
S
P
S
Site 24
S166
P
P
G
D
L
Q
Y
S
F
F
S
S
P
S
L
Site 25
S172
Y
S
F
F
S
S
P
S
L
A
N
S
I
R
S
Site 26
S176
S
S
P
S
L
A
N
S
I
R
S
P
E
E
R
Site 27
S179
S
L
A
N
S
I
R
S
P
E
E
R
A
T
P
Site 28
T185
R
S
P
E
E
R
A
T
P
H
A
K
S
E
R
Site 29
S190
R
A
T
P
H
A
K
S
E
R
P
S
H
P
L
Site 30
S194
H
A
K
S
E
R
P
S
H
P
L
Y
E
P
E
Site 31
Y198
E
R
P
S
H
P
L
Y
E
P
E
P
E
P
R
Site 32
S207
P
E
P
E
P
R
D
S
P
Q
P
G
Q
G
H
Site 33
S215
P
Q
P
G
Q
G
H
S
P
G
A
T
A
A
A
Site 34
T219
Q
G
H
S
P
G
A
T
A
A
A
T
G
L
P
Site 35
T223
P
G
A
T
A
A
A
T
G
L
P
P
E
P
E
Site 36
S233
P
P
E
P
E
P
D
S
T
D
Y
S
E
L
A
Site 37
T234
P
E
P
E
P
D
S
T
D
Y
S
E
L
A
D
Site 38
Y236
P
E
P
D
S
T
D
Y
S
E
L
A
D
A
D
Site 39
S237
E
P
D
S
T
D
Y
S
E
L
A
D
A
D
I
Site 40
S268
A
Q
A
L
E
P
P
S
P
E
P
E
P
Q
L
Site 41
S323
A
L
D
T
L
P
D
S
L
E
S
Q
L
L
D
Site 42
S369
P
L
R
L
D
L
C
S
P
H
G
P
P
G
P
Site 43
Y382
G
P
E
G
H
P
K
Y
A
L
R
R
T
D
R
Site 44
T387
P
K
Y
A
L
R
R
T
D
R
P
K
I
L
C
Site 45
S447
L
P
G
P
G
P
V
S
V
P
E
L
K
P
E
Site 46
S456
P
E
L
K
P
E
S
S
Q
T
P
V
V
S
T
Site 47
T458
L
K
P
E
S
S
Q
T
P
V
V
S
T
R
K
Site 48
S462
S
S
Q
T
P
V
V
S
T
R
K
G
K
C
R
Site 49
T463
S
Q
T
P
V
V
S
T
R
K
G
K
C
R
G
Site 50
S484
K
M
A
K
I
P
V
S
L
G
R
R
N
K
T
Site 51
T491
S
L
G
R
R
N
K
T
T
Y
K
V
S
S
L
Site 52
T492
L
G
R
R
N
K
T
T
Y
K
V
S
S
L
S
Site 53
Y493
G
R
R
N
K
T
T
Y
K
V
S
S
L
S
S
Site 54
S496
N
K
T
T
Y
K
V
S
S
L
S
S
S
L
S
Site 55
S497
K
T
T
Y
K
V
S
S
L
S
S
S
L
S
V
Site 56
S499
T
Y
K
V
S
S
L
S
S
S
L
S
V
E
G
Site 57
S500
Y
K
V
S
S
L
S
S
S
L
S
V
E
G
K
Site 58
S501
K
V
S
S
L
S
S
S
L
S
V
E
G
K
E
Site 59
S503
S
S
L
S
S
S
L
S
V
E
G
K
E
L
G
Site 60
S514
K
E
L
G
L
R
V
S
A
E
P
T
P
L
L
Site 61
T518
L
R
V
S
A
E
P
T
P
L
L
K
M
K
N
Site 62
S596
R
R
K
Q
K
L
A
S
P
Q
P
S
Y
A
A
Site 63
S600
K
L
A
S
P
Q
P
S
Y
A
A
D
A
N
D
Site 64
Y612
A
N
D
S
K
A
E
Y
S
D
V
L
A
K
L
Site 65
S626
L
A
F
L
N
R
Q
S
Q
C
A
G
R
C
S
Site 66
S633
S
Q
C
A
G
R
C
S
P
P
R
C
W
T
P
Site 67
T639
C
S
P
P
R
C
W
T
P
S
E
P
E
S
V
Site 68
S641
P
P
R
C
W
T
P
S
E
P
E
S
V
H
Q
Site 69
S645
W
T
P
S
E
P
E
S
V
H
Q
A
P
D
T
Site 70
T652
S
V
H
Q
A
P
D
T
Q
S
I
S
H
F
L
Site 71
S654
H
Q
A
P
D
T
Q
S
I
S
H
F
L
H
R
Site 72
S686
G
G
G
H
A
A
K
S
A
R
C
S
F
S
D
Site 73
S690
A
A
K
S
A
R
C
S
F
S
D
F
F
E
G
Site 74
S692
K
S
A
R
C
S
F
S
D
F
F
E
G
I
G
Site 75
T718
G
V
G
G
P
G
L
T
E
L
G
H
P
R
K
Site 76
T735
R
G
E
V
D
A
V
T
G
K
P
K
R
K
R
Site 77
S744
K
P
K
R
K
R
R
S
R
K
N
G
T
L
F
Site 78
T749
R
R
S
R
K
N
G
T
L
F
P
E
Q
V
P
Site 79
S757
L
F
P
E
Q
V
P
S
G
P
G
F
G
E
A
Site 80
T804
E
A
R
A
F
A
S
T
G
L
E
S
G
A
S
Site 81
S811
T
G
L
E
S
G
A
S
G
R
G
S
Y
Y
S
Site 82
S815
S
G
A
S
G
R
G
S
Y
Y
S
T
G
A
P
Site 83
Y816
G
A
S
G
R
G
S
Y
Y
S
T
G
A
P
S
Site 84
Y817
A
S
G
R
G
S
Y
Y
S
T
G
A
P
S
G
Site 85
S818
S
G
R
G
S
Y
Y
S
T
G
A
P
S
G
Q
Site 86
T819
G
R
G
S
Y
Y
S
T
G
A
P
S
G
Q
T
Site 87
S823
Y
Y
S
T
G
A
P
S
G
Q
T
E
L
S
Q
Site 88
S829
P
S
G
Q
T
E
L
S
Q
E
R
Q
N
L
F
Site 89
T837
Q
E
R
Q
N
L
F
T
G
Y
F
R
S
L
L
Site 90
Y839
R
Q
N
L
F
T
G
Y
F
R
S
L
L
D
S
Site 91
S842
L
F
T
G
Y
F
R
S
L
L
D
S
D
D
S
Site 92
S846
Y
F
R
S
L
L
D
S
D
D
S
S
D
L
L
Site 93
S849
S
L
L
D
S
D
D
S
S
D
L
L
D
F
A
Site 94
S858
D
L
L
D
F
A
L
S
A
S
R
P
E
S
R
Site 95
S860
L
D
F
A
L
S
A
S
R
P
E
S
R
K
A
Site 96
S864
L
S
A
S
R
P
E
S
R
K
A
S
G
T
Y
Site 97
S868
R
P
E
S
R
K
A
S
G
T
Y
A
G
P
P
Site 98
T870
E
S
R
K
A
S
G
T
Y
A
G
P
P
T
S
Site 99
Y871
S
R
K
A
S
G
T
Y
A
G
P
P
T
S
A
Site 100
S877
T
Y
A
G
P
P
T
S
A
L
P
A
Q
R
G
Site 101
T887
P
A
Q
R
G
L
A
T
F
P
S
R
G
A
K
Site 102
S890
R
G
L
A
T
F
P
S
R
G
A
K
A
S
P
Site 103
S896
P
S
R
G
A
K
A
S
P
V
A
V
G
S
S
Site 104
S910
S
G
A
G
A
D
P
S
F
Q
P
V
L
S
A
Site 105
S916
P
S
F
Q
P
V
L
S
A
R
Q
T
F
P
P
Site 106
T920
P
V
L
S
A
R
Q
T
F
P
P
G
R
A
A
Site 107
S928
F
P
P
G
R
A
A
S
Y
G
L
T
P
A
A
Site 108
T932
R
A
A
S
Y
G
L
T
P
A
A
S
D
C
R
Site 109
S936
Y
G
L
T
P
A
A
S
D
C
R
A
A
E
T
Site 110
T943
S
D
C
R
A
A
E
T
F
P
K
L
V
P
P
Site 111
S952
P
K
L
V
P
P
P
S
A
M
A
R
S
P
T
Site 112
S957
P
P
S
A
M
A
R
S
P
T
T
H
P
P
A
Site 113
T959
S
A
M
A
R
S
P
T
T
H
P
P
A
N
T
Site 114
T960
A
M
A
R
S
P
T
T
H
P
P
A
N
T
Y
Site 115
T966
T
T
H
P
P
A
N
T
Y
L
P
Q
Y
G
G
Site 116
Y967
T
H
P
P
A
N
T
Y
L
P
Q
Y
G
G
Y
Site 117
Y971
A
N
T
Y
L
P
Q
Y
G
G
Y
G
A
G
Q
Site 118
S979
G
G
Y
G
A
G
Q
S
V
F
A
P
T
K
P
Site 119
S999
C
A
N
S
K
D
C
S
F
A
Y
G
S
G
N
Site 120
Y1002
S
K
D
C
S
F
A
Y
G
S
G
N
S
L
P
Site 121
S1004
D
C
S
F
A
Y
G
S
G
N
S
L
P
A
S
Site 122
S1007
F
A
Y
G
S
G
N
S
L
P
A
S
P
S
S
Site 123
S1011
S
G
N
S
L
P
A
S
P
S
S
A
H
S
A
Site 124
S1013
N
S
L
P
A
S
P
S
S
A
H
S
A
G
Y
Site 125
S1014
S
L
P
A
S
P
S
S
A
H
S
A
G
Y
A
Site 126
S1017
A
S
P
S
S
A
H
S
A
G
Y
A
P
P
P
Site 127
Y1020
S
S
A
H
S
A
G
Y
A
P
P
P
T
G
G
Site 128
T1025
A
G
Y
A
P
P
P
T
G
G
P
C
L
P
P
Site 129
S1033
G
G
P
C
L
P
P
S
K
A
S
F
F
S
S
Site 130
S1036
C
L
P
P
S
K
A
S
F
F
S
S
S
E
G
Site 131
S1039
P
S
K
A
S
F
F
S
S
S
E
G
A
P
F
Site 132
S1040
S
K
A
S
F
F
S
S
S
E
G
A
P
F
S
Site 133
S1041
K
A
S
F
F
S
S
S
E
G
A
P
F
S
G
Site 134
S1047
S
S
E
G
A
P
F
S
G
S
A
P
T
P
L
Site 135
S1049
E
G
A
P
F
S
G
S
A
P
T
P
L
R
C
Site 136
T1052
P
F
S
G
S
A
P
T
P
L
R
C
D
S
R
Site 137
S1058
P
T
P
L
R
C
D
S
R
A
S
T
V
S
P
Site 138
S1061
L
R
C
D
S
R
A
S
T
V
S
P
G
G
Y
Site 139
T1062
R
C
D
S
R
A
S
T
V
S
P
G
G
Y
M
Site 140
S1064
D
S
R
A
S
T
V
S
P
G
G
Y
M
V
P
Site 141
Y1068
S
T
V
S
P
G
G
Y
M
V
P
K
G
T
T
Site 142
S1077
V
P
K
G
T
T
A
S
A
T
S
A
A
S
A
Site 143
T1079
K
G
T
T
A
S
A
T
S
A
A
S
A
A
S
Site 144
S1083
A
S
A
T
S
A
A
S
A
A
S
S
S
S
S
Site 145
S1086
T
S
A
A
S
A
A
S
S
S
S
S
S
F
Q
Site 146
S1087
S
A
A
S
A
A
S
S
S
S
S
S
F
Q
P
Site 147
S1088
A
A
S
A
A
S
S
S
S
S
S
F
Q
P
S
Site 148
S1089
A
S
A
A
S
S
S
S
S
S
F
Q
P
S
P
Site 149
S1090
S
A
A
S
S
S
S
S
S
F
Q
P
S
P
E
Site 150
S1091
A
A
S
S
S
S
S
S
F
Q
P
S
P
E
N
Site 151
S1095
S
S
S
S
F
Q
P
S
P
E
N
C
R
Q
F
Site 152
Y1114
Q
W
P
F
R
Q
G
Y
G
G
L
D
W
A
S
Site 153
S1121
Y
G
G
L
D
W
A
S
E
A
F
S
Q
L
Y
Site 154
S1125
D
W
A
S
E
A
F
S
Q
L
Y
N
P
S
F
Site 155
Y1128
S
E
A
F
S
Q
L
Y
N
P
S
F
D
C
H
Site 156
S1131
F
S
Q
L
Y
N
P
S
F
D
C
H
V
S
E
Site 157
S1137
P
S
F
D
C
H
V
S
E
P
N
V
I
L
D
Site 158
Y1148
V
I
L
D
I
S
N
Y
T
P
Q
K
V
K
Q
Site 159
T1149
I
L
D
I
S
N
Y
T
P
Q
K
V
K
Q
Q
Site 160
S1160
V
K
Q
Q
T
A
V
S
E
T
F
S
E
S
S
Site 161
T1162
Q
Q
T
A
V
S
E
T
F
S
E
S
S
S
D
Site 162
S1164
T
A
V
S
E
T
F
S
E
S
S
S
D
S
T
Site 163
S1166
V
S
E
T
F
S
E
S
S
S
D
S
T
Q
F
Site 164
S1167
S
E
T
F
S
E
S
S
S
D
S
T
Q
F
N
Site 165
S1168
E
T
F
S
E
S
S
S
D
S
T
Q
F
N
Q
Site 166
S1170
F
S
E
S
S
S
D
S
T
Q
F
N
Q
P
V
Site 167
T1171
S
E
S
S
S
D
S
T
Q
F
N
Q
P
V
G
Site 168
S1187
G
G
F
R
R
A
N
S
E
A
S
S
S
E
G
Site 169
S1190
R
R
A
N
S
E
A
S
S
S
E
G
Q
S
S
Site 170
S1191
R
A
N
S
E
A
S
S
S
E
G
Q
S
S
L
Site 171
S1192
A
N
S
E
A
S
S
S
E
G
Q
S
S
L
S
Site 172
S1196
A
S
S
S
E
G
Q
S
S
L
S
S
L
E
K
Site 173
S1197
S
S
S
E
G
Q
S
S
L
S
S
L
E
K
L
Site 174
S1199
S
E
G
Q
S
S
L
S
S
L
E
K
L
M
M
Site 175
S1200
E
G
Q
S
S
L
S
S
L
E
K
L
M
M
D
Site 176
Y1217
E
A
S
S
A
P
G
Y
N
W
N
Q
S
V
L
Site 177
S1222
P
G
Y
N
W
N
Q
S
V
L
F
Q
S
S
S
Site 178
S1227
N
Q
S
V
L
F
Q
S
S
S
K
P
G
R
G
Site 179
S1228
Q
S
V
L
F
Q
S
S
S
K
P
G
R
G
R
Site 180
S1229
S
V
L
F
Q
S
S
S
K
P
G
R
G
R
R
Site 181
S1245
K
V
D
L
F
E
A
S
H
L
G
F
P
T
S
Site 182
S1258
T
S
A
S
A
A
A
S
G
Y
P
S
K
R
S
Site 183
Y1260
A
S
A
A
A
S
G
Y
P
S
K
R
S
T
G
Site 184
S1262
A
A
A
S
G
Y
P
S
K
R
S
T
G
P
R
Site 185
S1265
S
G
Y
P
S
K
R
S
T
G
P
R
Q
P
R
Site 186
T1266
G
Y
P
S
K
R
S
T
G
P
R
Q
P
R
G
Site 187
S1281
G
R
G
G
G
A
C
S
A
K
K
E
R
G
G
Site 188
S1309
V
N
P
L
F
Q
D
S
P
D
L
G
L
D
Y
Site 189
Y1316
S
P
D
L
G
L
D
Y
Y
S
G
D
S
S
M
Site 190
Y1317
P
D
L
G
L
D
Y
Y
S
G
D
S
S
M
S
Site 191
S1318
D
L
G
L
D
Y
Y
S
G
D
S
S
M
S
P
Site 192
S1321
L
D
Y
Y
S
G
D
S
S
M
S
P
L
P
S
Site 193
S1322
D
Y
Y
S
G
D
S
S
M
S
P
L
P
S
Q
Site 194
S1324
Y
S
G
D
S
S
M
S
P
L
P
S
Q
S
R
Site 195
S1328
S
S
M
S
P
L
P
S
Q
S
R
A
F
G
V
Site 196
S1330
M
S
P
L
P
S
Q
S
R
A
F
G
V
G
E
Site 197
Y1347
P
C
D
F
I
G
P
Y
S
M
N
P
S
T
P
Site 198
S1348
C
D
F
I
G
P
Y
S
M
N
P
S
T
P
S
Site 199
S1352
G
P
Y
S
M
N
P
S
T
P
S
D
G
T
F
Site 200
T1353
P
Y
S
M
N
P
S
T
P
S
D
G
T
F
G
Site 201
S1355
S
M
N
P
S
T
P
S
D
G
T
F
G
Q
G
Site 202
T1358
P
S
T
P
S
D
G
T
F
G
Q
G
F
H
C
Site 203
S1367
G
Q
G
F
H
C
D
S
P
S
L
G
A
P
E
Site 204
S1369
G
F
H
C
D
S
P
S
L
G
A
P
E
L
D
Site 205
T1388
P
P
L
A
H
P
P
T
V
F
D
A
G
L
Q
Site 206
Y1398
D
A
G
L
Q
K
A
Y
S
P
T
C
S
P
T
Site 207
S1399
A
G
L
Q
K
A
Y
S
P
T
C
S
P
T
L
Site 208
T1401
L
Q
K
A
Y
S
P
T
C
S
P
T
L
G
F
Site 209
S1403
K
A
Y
S
P
T
C
S
P
T
L
G
F
K
E
Site 210
T1405
Y
S
P
T
C
S
P
T
L
G
F
K
E
E
L
Site 211
Y1456
L
P
L
G
Q
P
H
Y
D
S
P
S
C
K
G
Site 212
S1458
L
G
Q
P
H
Y
D
S
P
S
C
K
G
T
A
Site 213
T1464
D
S
P
S
C
K
G
T
A
Y
W
Y
P
P
G
Site 214
Y1466
P
S
C
K
G
T
A
Y
W
Y
P
P
G
S
A
Site 215
Y1468
C
K
G
T
A
Y
W
Y
P
P
G
S
A
A
R
Site 216
S1472
A
Y
W
Y
P
P
G
S
A
A
R
S
P
P
Y
Site 217
S1476
P
P
G
S
A
A
R
S
P
P
Y
E
G
K
V
Site 218
Y1479
S
A
A
R
S
P
P
Y
E
G
K
V
G
T
G
Site 219
S1501
R
T
E
A
A
C
L
S
A
P
H
L
A
S
P
Site 220
S1507
L
S
A
P
H
L
A
S
P
P
A
T
P
K
A
Site 221
T1511
H
L
A
S
P
P
A
T
P
K
A
D
K
E
P
Site 222
S1549
L
L
S
D
L
T
L
S
P
V
P
R
D
S
L
Site 223
S1555
L
S
P
V
P
R
D
S
L
L
P
L
Q
D
T
Site 224
T1562
S
L
L
P
L
Q
D
T
A
Y
R
Y
P
G
F
Site 225
Y1564
L
P
L
Q
D
T
A
Y
R
Y
P
G
F
M
P
Site 226
Y1566
L
Q
D
T
A
Y
R
Y
P
G
F
M
P
Q
A
Site 227
T1597
A
E
P
H
P
E
D
T
F
T
V
T
S
L
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation