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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NBPF14
Full Name:
Neuroblastoma breakpoint family member 14
Alias:
Type:
Mass (Da):
105853
Number AA:
921
UniProt ID:
Q5TI25
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y26
Q
A
E
E
L
R
Q
Y
K
V
L
V
H
A
Q
Site 2
T38
H
A
Q
E
R
E
L
T
Q
L
R
E
K
L
R
Site 3
S51
L
R
E
G
R
D
A
S
R
S
L
N
E
H
L
Site 4
S53
E
G
R
D
A
S
R
S
L
N
E
H
L
Q
A
Site 5
T63
E
H
L
Q
A
L
L
T
P
D
E
P
D
K
S
Site 6
S70
T
P
D
E
P
D
K
S
Q
G
Q
D
L
Q
E
Site 7
S94
Q
H
L
V
Q
K
L
S
P
E
N
D
N
D
D
Site 8
S116
V
A
E
K
V
Q
K
S
S
A
P
R
E
M
Q
Site 9
S117
A
E
K
V
Q
K
S
S
A
P
R
E
M
Q
K
Site 10
S134
E
K
E
V
P
E
D
S
L
E
E
C
A
I
T
Site 11
T141
S
L
E
E
C
A
I
T
C
S
N
S
H
G
P
Site 12
Y149
C
S
N
S
H
G
P
Y
D
S
N
Q
P
H
R
Site 13
S151
N
S
H
G
P
Y
D
S
N
Q
P
H
R
K
T
Site 14
T158
S
N
Q
P
H
R
K
T
K
I
T
F
E
E
D
Site 15
T161
P
H
R
K
T
K
I
T
F
E
E
D
K
V
D
Site 16
S169
F
E
E
D
K
V
D
S
T
L
I
G
S
S
S
Site 17
T170
E
E
D
K
V
D
S
T
L
I
G
S
S
S
H
Site 18
S176
S
T
L
I
G
S
S
S
H
V
E
W
E
D
A
Site 19
S204
E
E
E
K
G
P
V
S
P
R
N
L
Q
E
S
Site 20
S211
S
P
R
N
L
Q
E
S
E
E
E
E
V
P
Q
Site 21
S220
E
E
E
V
P
Q
E
S
W
D
E
G
Y
S
T
Site 22
Y225
Q
E
S
W
D
E
G
Y
S
T
L
S
I
P
P
Site 23
S226
E
S
W
D
E
G
Y
S
T
L
S
I
P
P
E
Site 24
T227
S
W
D
E
G
Y
S
T
L
S
I
P
P
E
M
Site 25
S229
D
E
G
Y
S
T
L
S
I
P
P
E
M
L
A
Site 26
S237
I
P
P
E
M
L
A
S
Y
K
S
Y
S
S
T
Site 27
Y238
P
P
E
M
L
A
S
Y
K
S
Y
S
S
T
F
Site 28
S240
E
M
L
A
S
Y
K
S
Y
S
S
T
F
H
S
Site 29
S242
L
A
S
Y
K
S
Y
S
S
T
F
H
S
L
E
Site 30
S243
A
S
Y
K
S
Y
S
S
T
F
H
S
L
E
E
Site 31
T244
S
Y
K
S
Y
S
S
T
F
H
S
L
E
E
Q
Site 32
S247
S
Y
S
S
T
F
H
S
L
E
E
Q
Q
V
C
Site 33
S280
E
A
T
G
P
R
L
S
R
E
L
L
D
E
K
Site 34
S295
G
P
E
V
L
Q
D
S
L
D
R
C
Y
S
T
Site 35
Y300
Q
D
S
L
D
R
C
Y
S
T
P
S
G
C
L
Site 36
S301
D
S
L
D
R
C
Y
S
T
P
S
G
C
L
E
Site 37
T302
S
L
D
R
C
Y
S
T
P
S
G
C
L
E
L
Site 38
S304
D
R
C
Y
S
T
P
S
G
C
L
E
L
T
D
Site 39
T310
P
S
G
C
L
E
L
T
D
S
C
Q
P
Y
R
Site 40
S312
G
C
L
E
L
T
D
S
C
Q
P
Y
R
S
A
Site 41
Y316
L
T
D
S
C
Q
P
Y
R
S
A
F
Y
V
L
Site 42
Y321
Q
P
Y
R
S
A
F
Y
V
L
E
Q
Q
R
V
Site 43
Y340
N
M
D
E
I
E
K
Y
Q
E
V
E
E
D
Q
Site 44
S350
V
E
E
D
Q
D
P
S
C
P
R
L
S
R
E
Site 45
S355
D
P
S
C
P
R
L
S
R
E
L
L
D
E
K
Site 46
S370
E
P
E
V
L
Q
D
S
L
G
R
C
Y
S
T
Site 47
Y375
Q
D
S
L
G
R
C
Y
S
T
P
S
G
Y
L
Site 48
S376
D
S
L
G
R
C
Y
S
T
P
S
G
Y
L
E
Site 49
T377
S
L
G
R
C
Y
S
T
P
S
G
Y
L
E
L
Site 50
S379
G
R
C
Y
S
T
P
S
G
Y
L
E
L
P
D
Site 51
Y391
L
P
D
L
G
Q
P
Y
S
S
A
V
Y
S
L
Site 52
S392
P
D
L
G
Q
P
Y
S
S
A
V
Y
S
L
E
Site 53
S393
D
L
G
Q
P
Y
S
S
A
V
Y
S
L
E
E
Site 54
S397
P
Y
S
S
A
V
Y
S
L
E
E
Q
Y
L
G
Site 55
S430
G
P
P
C
P
R
L
S
R
E
L
L
E
V
V
Site 56
S445
E
P
E
V
L
Q
D
S
L
D
R
C
Y
S
T
Site 57
Y450
Q
D
S
L
D
R
C
Y
S
T
P
S
S
C
L
Site 58
S451
D
S
L
D
R
C
Y
S
T
P
S
S
C
L
E
Site 59
T452
S
L
D
R
C
Y
S
T
P
S
S
C
L
E
Q
Site 60
S455
R
C
Y
S
T
P
S
S
C
L
E
Q
P
D
S
Site 61
S462
S
C
L
E
Q
P
D
S
C
Q
P
Y
G
S
S
Site 62
Y466
Q
P
D
S
C
Q
P
Y
G
S
S
F
Y
A
L
Site 63
S469
S
C
Q
P
Y
G
S
S
F
Y
A
L
E
E
K
Site 64
S481
E
E
K
H
V
G
F
S
L
D
V
G
E
I
E
Site 65
S501
K
K
R
R
G
R
R
S
K
K
E
R
R
R
G
Site 66
S524
N
P
P
C
P
R
L
S
R
E
L
L
D
E
K
Site 67
Y560
L
T
D
S
C
Q
P
Y
R
S
A
F
Y
I
L
Site 68
Y584
D
M
D
E
I
E
K
Y
Q
E
V
E
E
D
Q
Site 69
S594
V
E
E
D
Q
D
P
S
C
P
R
L
S
G
E
Site 70
S599
D
P
S
C
P
R
L
S
G
E
L
L
D
E
K
Site 71
S614
E
P
E
V
L
Q
E
S
L
D
R
C
Y
S
T
Site 72
Y619
Q
E
S
L
D
R
C
Y
S
T
P
S
G
C
L
Site 73
S620
E
S
L
D
R
C
Y
S
T
P
S
G
C
L
E
Site 74
S844
P
P
C
P
R
L
N
S
M
L
M
E
V
E
E
Site 75
S858
E
P
E
V
L
Q
D
S
L
D
I
C
Y
S
T
Site 76
Y863
Q
D
S
L
D
I
C
Y
S
T
P
S
M
Y
F
Site 77
Y869
C
Y
S
T
P
S
M
Y
F
E
L
P
D
S
F
Site 78
Y879
L
P
D
S
F
Q
H
Y
R
S
V
F
Y
S
F
Site 79
S881
D
S
F
Q
H
Y
R
S
V
F
Y
S
F
E
E
Site 80
S885
H
Y
R
S
V
F
Y
S
F
E
E
E
H
I
S
Site 81
S892
S
F
E
E
E
H
I
S
F
A
L
Y
V
D
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation