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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MEI1
Full Name:
Meiosis inhibitor protein 1
Alias:
Meiosis defective protein 1
Type:
Mass (Da):
141161
Number AA:
1274
UniProt ID:
Q5TIA1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
R
Q
A
A
T
A
G
T
P
G
P
R
R
E
E
Site 2
Y29
L
L
F
E
R
A
H
Y
R
H
D
P
R
W
L
Site 3
S58
L
L
P
D
P
G
V
S
L
V
R
K
K
H
M
Site 4
T130
T
Q
L
K
L
E
Q
T
I
R
C
L
L
D
E
Site 5
S147
K
E
L
C
N
M
P
S
M
R
G
S
L
A
T
Site 6
S197
P
S
E
G
I
Q
A
S
V
C
Y
L
Y
G
K
Site 7
Y202
Q
A
S
V
C
Y
L
Y
G
K
L
Y
S
S
P
Site 8
S277
A
K
N
I
E
G
S
S
G
N
T
S
L
P
L
Site 9
T280
I
E
G
S
S
G
N
T
S
L
P
L
V
L
K
Site 10
S281
E
G
S
S
G
N
T
S
L
P
L
V
L
K
K
Site 11
S337
F
E
H
L
S
S
S
S
E
V
L
V
W
S
S
Site 12
S377
V
V
R
S
L
Q
G
S
L
K
M
N
N
I
E
Site 13
T398
L
L
F
A
E
I
L
T
R
Q
P
E
E
I
K
Site 14
S410
E
I
K
L
F
T
S
S
A
M
C
R
D
A
G
Site 15
S449
F
L
R
K
D
H
Q
S
T
P
P
V
Q
Y
G
Site 16
T450
L
R
K
D
H
Q
S
T
P
P
V
Q
Y
G
E
Site 17
S473
L
N
R
C
A
E
F
S
Q
T
L
L
S
R
R
Site 18
T475
R
C
A
E
F
S
Q
T
L
L
S
R
R
P
L
Site 19
S478
E
F
S
Q
T
L
L
S
R
R
P
L
G
H
A
Site 20
S486
R
R
P
L
G
H
A
S
S
R
D
S
E
K
A
Site 21
S487
R
P
L
G
H
A
S
S
R
D
S
E
K
A
I
Site 22
S490
G
H
A
S
S
R
D
S
E
K
A
I
L
Q
R
Site 23
S503
Q
R
G
K
F
L
L
S
T
L
E
G
F
R
S
Site 24
T504
R
G
K
F
L
L
S
T
L
E
G
F
R
S
A
Site 25
T530
S
A
Q
E
N
P
F
T
A
P
S
A
K
K
E
Site 26
T539
P
S
A
K
K
E
D
T
L
E
A
F
S
E
F
Site 27
T566
V
M
R
H
L
E
Q
T
T
H
P
A
L
M
E
Site 28
S594
P
H
M
K
E
K
F
S
K
K
L
A
S
S
S
Site 29
S599
K
F
S
K
K
L
A
S
S
S
F
I
R
L
T
Site 30
S601
S
K
K
L
A
S
S
S
F
I
R
L
T
L
E
Site 31
S615
E
L
K
A
R
F
C
S
G
L
S
H
S
A
L
Site 32
S639
Y
M
C
L
N
L
L
S
A
P
E
K
T
G
P
Site 33
T644
L
L
S
A
P
E
K
T
G
P
P
S
K
E
E
Site 34
S648
P
E
K
T
G
P
P
S
K
E
E
L
S
A
V
Site 35
S653
P
P
S
K
E
E
L
S
A
V
S
E
L
L
Q
Site 36
S667
Q
H
G
L
P
Q
I
S
S
R
S
P
E
S
L
Site 37
S668
H
G
L
P
Q
I
S
S
R
S
P
E
S
L
A
Site 38
S670
L
P
Q
I
S
S
R
S
P
E
S
L
A
F
L
Site 39
S673
I
S
S
R
S
P
E
S
L
A
F
L
S
D
R
Site 40
S678
P
E
S
L
A
F
L
S
D
R
Q
Y
M
E
G
Site 41
Y682
A
F
L
S
D
R
Q
Y
M
E
G
A
A
R
Q
Site 42
S710
I
H
E
D
R
F
V
S
E
A
E
L
F
E
A
Site 43
S724
A
V
Q
S
F
L
L
S
L
Q
D
Q
G
E
R
Site 44
T753
I
C
Q
D
K
D
N
T
L
R
E
T
M
V
S
Site 45
T757
K
D
N
T
L
R
E
T
M
V
S
A
I
R
K
Site 46
S760
T
L
R
E
T
M
V
S
A
I
R
K
F
L
E
Site 47
T777
P
D
L
Q
L
V
Y
T
H
H
P
L
L
L
R
Site 48
Y812
F
F
W
E
E
S
S
Y
E
E
L
D
D
V
T
Site 49
T819
Y
E
E
L
D
D
V
T
S
A
G
Q
P
A
L
Site 50
T868
K
V
L
I
S
L
R
T
F
L
R
R
N
E
D
Site 51
S900
L
L
V
E
H
G
A
S
P
S
G
A
S
G
N
Site 52
S902
V
E
H
G
A
S
P
S
G
A
S
G
N
L
P
Site 53
S913
G
N
L
P
L
L
L
S
L
L
S
L
M
Q
L
Site 54
S924
L
M
Q
L
R
N
V
S
E
Q
E
L
D
S
V
Site 55
S930
V
S
E
Q
E
L
D
S
V
A
M
K
L
L
H
Site 56
S940
M
K
L
L
H
Q
V
S
K
L
C
G
K
C
S
Site 57
Y962
Q
P
S
F
N
F
L
Y
W
S
L
H
Q
T
T
Site 58
T968
L
Y
W
S
L
H
Q
T
T
P
S
S
Q
K
R
Site 59
T969
Y
W
S
L
H
Q
T
T
P
S
S
Q
K
R
A
Site 60
S972
L
H
Q
T
T
P
S
S
Q
K
R
A
A
A
V
Site 61
S1003
L
T
L
A
K
A
D
S
P
R
T
A
L
L
C
Site 62
S1018
S
A
W
L
L
T
A
S
F
S
A
Q
Q
H
K
Site 63
S1020
W
L
L
T
A
S
F
S
A
Q
Q
H
K
G
S
Site 64
T1033
G
S
L
Q
V
H
Q
T
L
S
V
E
M
D
Q
Site 65
S1046
D
Q
V
L
K
A
L
S
F
P
K
K
K
A
A
Site 66
Y1134
C
L
E
A
L
L
D
Y
L
D
A
R
S
P
D
Site 67
S1148
D
I
A
L
H
V
A
S
Q
P
W
N
R
F
L
Site 68
T1177
P
E
I
L
R
L
M
T
L
F
M
R
Y
R
S
Site 69
S1184
T
L
F
M
R
Y
R
S
S
S
V
L
S
H
E
Site 70
S1185
L
F
M
R
Y
R
S
S
S
V
L
S
H
E
E
Site 71
S1186
F
M
R
Y
R
S
S
S
V
L
S
H
E
E
V
Site 72
S1189
Y
R
S
S
S
V
L
S
H
E
E
V
G
D
V
Site 73
S1233
M
G
H
L
A
D
H
S
M
A
Q
T
L
Q
A
Site 74
T1237
A
D
H
S
M
A
Q
T
L
Q
A
S
L
E
G
Site 75
S1241
M
A
Q
T
L
Q
A
S
L
E
G
L
P
P
S
Site 76
S1248
S
L
E
G
L
P
P
S
T
S
S
G
Q
P
P
Site 77
T1249
L
E
G
L
P
P
S
T
S
S
G
Q
P
P
L
Site 78
S1250
E
G
L
P
P
S
T
S
S
G
Q
P
P
L
Q
Site 79
S1251
G
L
P
P
S
T
S
S
G
Q
P
P
L
Q
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation