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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MEX3C
Full Name:
RNA-binding protein MEX3C
Alias:
FLJ38871; Mex-3 C; Ring finger and KH domain containing 2; RING finger and KH domain-containing protein 2; RING finger protein 194; RNA-binding protein MEX3C: RING finger and KH domain-containing protein 2: RING finger protein 194: Putative uncharacterized protein; RNF194
Type:
Unknown function
Mass (Da):
69366
Number AA:
659
UniProt ID:
Q5U5Q3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S36
P
P
P
L
P
P
P
S
G
G
P
E
L
E
G
Site 2
S61
A
L
G
L
D
D
P
S
P
A
E
P
G
A
P
Site 3
S88
A
R
R
A
A
E
L
S
P
E
E
R
A
P
P
Site 4
S139
E
A
E
E
E
D
R
S
S
L
L
L
L
S
P
Site 5
S140
A
E
E
E
D
R
S
S
L
L
L
L
S
P
P
Site 6
S152
S
P
P
A
A
T
A
S
Q
T
Q
Q
I
P
G
Site 7
S229
A
A
L
L
R
R
K
S
V
N
T
T
E
C
V
Site 8
T232
L
R
R
K
S
V
N
T
T
E
C
V
P
V
P
Site 9
T233
R
R
K
S
V
N
T
T
E
C
V
P
V
P
S
Site 10
T262
I
K
A
L
R
A
K
T
N
T
Y
I
K
T
P
Site 11
T264
A
L
R
A
K
T
N
T
Y
I
K
T
P
V
R
Site 12
T268
K
T
N
T
Y
I
K
T
P
V
R
G
E
E
P
Site 13
S295
M
A
K
R
E
I
L
S
A
A
E
H
F
S
M
Site 14
S301
L
S
A
A
E
H
F
S
M
I
R
A
S
R
N
Site 15
S306
H
F
S
M
I
R
A
S
R
N
K
N
G
P
A
Site 16
S320
A
L
G
G
L
S
C
S
P
N
L
P
G
Q
T
Site 17
T328
P
N
L
P
G
Q
T
T
V
Q
V
R
V
P
Y
Site 18
T356
I
K
R
I
Q
Q
Q
T
H
T
Y
I
V
T
P
Site 19
T358
R
I
Q
Q
Q
T
H
T
Y
I
V
T
P
S
R
Site 20
T362
Q
T
H
T
Y
I
V
T
P
S
R
D
K
E
P
Site 21
S364
H
T
Y
I
V
T
P
S
R
D
K
E
P
V
F
Site 22
T374
K
E
P
V
F
E
V
T
G
M
P
E
N
V
D
Site 23
Y409
N
E
E
N
D
F
H
Y
N
G
T
D
V
S
F
Site 24
S415
H
Y
N
G
T
D
V
S
F
E
G
G
T
L
G
Site 25
S423
F
E
G
G
T
L
G
S
A
W
L
S
S
N
P
Site 26
S427
T
L
G
S
A
W
L
S
S
N
P
V
P
P
S
Site 27
S428
L
G
S
A
W
L
S
S
N
P
V
P
P
S
R
Site 28
S434
S
S
N
P
V
P
P
S
R
A
R
M
I
S
N
Site 29
S440
P
S
R
A
R
M
I
S
N
Y
R
N
D
S
S
Site 30
Y442
R
A
R
M
I
S
N
Y
R
N
D
S
S
S
S
Site 31
S446
I
S
N
Y
R
N
D
S
S
S
S
L
G
S
G
Site 32
S447
S
N
Y
R
N
D
S
S
S
S
L
G
S
G
S
Site 33
S448
N
Y
R
N
D
S
S
S
S
L
G
S
G
S
T
Site 34
S449
Y
R
N
D
S
S
S
S
L
G
S
G
S
T
D
Site 35
S452
D
S
S
S
S
L
G
S
G
S
T
D
S
Y
F
Site 36
S454
S
S
S
L
G
S
G
S
T
D
S
Y
F
G
S
Site 37
T455
S
S
L
G
S
G
S
T
D
S
Y
F
G
S
N
Site 38
S457
L
G
S
G
S
T
D
S
Y
F
G
S
N
R
L
Site 39
Y458
G
S
G
S
T
D
S
Y
F
G
S
N
R
L
A
Site 40
S461
S
T
D
S
Y
F
G
S
N
R
L
A
D
F
S
Site 41
S468
S
N
R
L
A
D
F
S
P
T
S
P
F
S
T
Site 42
T470
R
L
A
D
F
S
P
T
S
P
F
S
T
G
N
Site 43
S471
L
A
D
F
S
P
T
S
P
F
S
T
G
N
F
Site 44
S474
F
S
P
T
S
P
F
S
T
G
N
F
W
F
G
Site 45
T475
S
P
T
S
P
F
S
T
G
N
F
W
F
G
D
Site 46
T483
G
N
F
W
F
G
D
T
L
P
S
V
G
S
E
Site 47
S486
W
F
G
D
T
L
P
S
V
G
S
E
D
L
A
Site 48
S496
S
E
D
L
A
V
D
S
P
A
F
D
S
L
P
Site 49
S501
V
D
S
P
A
F
D
S
L
P
T
S
A
Q
T
Site 50
S505
A
F
D
S
L
P
T
S
A
Q
T
I
W
T
P
Site 51
T511
T
S
A
Q
T
I
W
T
P
F
E
P
V
N
P
Site 52
S520
F
E
P
V
N
P
L
S
G
F
G
S
D
P
S
Site 53
S524
N
P
L
S
G
F
G
S
D
P
S
G
N
M
K
Site 54
S527
S
G
F
G
S
D
P
S
G
N
M
K
T
Q
R
Site 55
T532
D
P
S
G
N
M
K
T
Q
R
R
G
S
Q
P
Site 56
S537
M
K
T
Q
R
R
G
S
Q
P
S
T
P
R
L
Site 57
S540
Q
R
R
G
S
Q
P
S
T
P
R
L
S
P
T
Site 58
T541
R
R
G
S
Q
P
S
T
P
R
L
S
P
T
F
Site 59
S545
Q
P
S
T
P
R
L
S
P
T
F
P
E
S
I
Site 60
T547
S
T
P
R
L
S
P
T
F
P
E
S
I
E
H
Site 61
S551
L
S
P
T
F
P
E
S
I
E
H
P
L
A
R
Site 62
S562
P
L
A
R
R
V
R
S
D
P
P
S
T
G
N
Site 63
S566
R
V
R
S
D
P
P
S
T
G
N
H
V
G
L
Site 64
S581
P
I
Y
I
P
A
F
S
N
G
T
N
S
Y
S
Site 65
T584
I
P
A
F
S
N
G
T
N
S
Y
S
S
S
N
Site 66
S586
A
F
S
N
G
T
N
S
Y
S
S
S
N
G
G
Site 67
Y587
F
S
N
G
T
N
S
Y
S
S
S
N
G
G
S
Site 68
S588
S
N
G
T
N
S
Y
S
S
S
N
G
G
S
T
Site 69
S589
N
G
T
N
S
Y
S
S
S
N
G
G
S
T
S
Site 70
S590
G
T
N
S
Y
S
S
S
N
G
G
S
T
S
S
Site 71
S594
Y
S
S
S
N
G
G
S
T
S
S
S
P
P
E
Site 72
T595
S
S
S
N
G
G
S
T
S
S
S
P
P
E
S
Site 73
S596
S
S
N
G
G
S
T
S
S
S
P
P
E
S
R
Site 74
S597
S
N
G
G
S
T
S
S
S
P
P
E
S
R
R
Site 75
S598
N
G
G
S
T
S
S
S
P
P
E
S
R
R
K
Site 76
S602
T
S
S
S
P
P
E
S
R
R
K
H
D
C
V
Site 77
T641
N
K
I
C
E
K
R
T
P
S
C
P
V
C
Q
Site 78
S643
I
C
E
K
R
T
P
S
C
P
V
C
Q
T
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation