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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AGBL2
Full Name:
Cytosolic carboxypeptidase 2
Alias:
ATP/GTP-binding protein-like 2
Type:
Mass (Da):
104194
Number AA:
902
UniProt ID:
Q5U5Z8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y17
K
Q
T
I
P
D
P
Y
E
D
F
M
Y
R
H
Site 2
Y22
D
P
Y
E
D
F
M
Y
R
H
L
Q
Y
Y
G
Site 3
Y28
M
Y
R
H
L
Q
Y
Y
G
Y
F
K
A
Q
R
Site 4
Y30
R
H
L
Q
Y
Y
G
Y
F
K
A
Q
R
G
S
Site 5
S37
Y
F
K
A
Q
R
G
S
L
P
N
S
A
T
H
Site 6
S41
Q
R
G
S
L
P
N
S
A
T
H
Q
H
V
R
Site 7
T70
K
D
D
L
I
P
D
T
L
Q
K
E
K
L
L
Site 8
S81
E
K
L
L
W
P
I
S
L
S
S
A
V
H
R
Site 9
S110
W
M
Q
W
R
G
L
S
S
L
Q
P
P
P
P
Site 10
S111
M
Q
W
R
G
L
S
S
L
Q
P
P
P
P
R
Site 11
S122
P
P
P
R
F
K
D
S
P
A
S
A
F
R
V
Site 12
S125
R
F
K
D
S
P
A
S
A
F
R
V
A
G
I
Site 13
S135
R
V
A
G
I
T
D
S
H
M
L
S
L
P
H
Site 14
S139
I
T
D
S
H
M
L
S
L
P
H
L
R
S
R
Site 15
S145
L
S
L
P
H
L
R
S
R
Q
L
L
Y
D
E
Site 16
Y150
L
R
S
R
Q
L
L
Y
D
E
L
D
E
V
N
Site 17
S168
R
E
P
Q
E
L
F
S
I
L
S
T
K
R
P
Site 18
S171
Q
E
L
F
S
I
L
S
T
K
R
P
L
Q
A
Site 19
T172
E
L
F
S
I
L
S
T
K
R
P
L
Q
A
P
Site 20
Y204
W
A
P
P
Q
P
E
Y
F
Y
Q
P
K
G
N
Site 21
Y206
P
P
Q
P
E
Y
F
Y
Q
P
K
G
N
E
K
Site 22
T224
I
V
G
E
K
K
G
T
V
V
Y
Q
L
D
S
Site 23
Y227
E
K
K
G
T
V
V
Y
Q
L
D
S
V
P
I
Site 24
S237
D
S
V
P
I
E
G
S
Y
F
T
S
S
R
V
Site 25
Y238
S
V
P
I
E
G
S
Y
F
T
S
S
R
V
G
Site 26
S241
I
E
G
S
Y
F
T
S
S
R
V
G
G
K
R
Site 27
S242
E
G
S
Y
F
T
S
S
R
V
G
G
K
R
G
Site 28
T257
I
V
K
E
L
A
V
T
L
Q
G
P
E
D
N
Site 29
T265
L
Q
G
P
E
D
N
T
L
L
F
E
S
R
F
Site 30
S270
D
N
T
L
L
F
E
S
R
F
E
S
G
N
L
Site 31
S274
L
F
E
S
R
F
E
S
G
N
L
Q
K
A
V
Site 32
T285
Q
K
A
V
R
V
D
T
Y
E
Y
E
L
T
L
Site 33
Y286
K
A
V
R
V
D
T
Y
E
Y
E
L
T
L
R
Site 34
T291
D
T
Y
E
Y
E
L
T
L
R
T
D
L
Y
T
Site 35
Y297
L
T
L
R
T
D
L
Y
T
N
K
H
T
Q
W
Site 36
T317
Q
N
T
R
K
D
A
T
Y
R
F
T
I
V
N
Site 37
Y318
N
T
R
K
D
A
T
Y
R
F
T
I
V
N
L
Site 38
T321
K
D
A
T
Y
R
F
T
I
V
N
L
L
K
P
Site 39
Y341
V
G
M
K
P
L
L
Y
S
Q
L
D
A
N
T
Site 40
S342
G
M
K
P
L
L
Y
S
Q
L
D
A
N
T
R
Site 41
Y362
R
E
G
N
E
I
K
Y
Y
K
N
N
T
D
D
Site 42
Y363
E
G
N
E
I
K
Y
Y
K
N
N
T
D
D
G
Site 43
Y406
T
Y
T
D
L
Q
C
Y
L
L
S
V
A
N
N
Site 44
S428
K
L
Q
T
L
C
R
S
L
A
G
N
T
V
Y
Site 45
S443
L
L
T
I
T
N
P
S
Q
T
P
Q
E
A
A
Site 46
T445
T
I
T
N
P
S
Q
T
P
Q
E
A
A
A
K
Site 47
S458
A
K
K
A
V
V
L
S
A
R
V
H
P
G
E
Site 48
S469
H
P
G
E
S
N
G
S
W
V
M
K
G
F
L
Site 49
S514
I
V
G
N
Y
R
C
S
L
A
G
R
D
L
N
Site 50
Y524
G
R
D
L
N
R
H
Y
K
T
I
L
K
E
S
Site 51
T526
D
L
N
R
H
Y
K
T
I
L
K
E
S
F
P
Site 52
Y554
E
E
R
E
V
L
L
Y
C
D
F
H
G
H
S
Site 53
Y569
R
K
N
N
I
F
L
Y
G
C
N
N
N
N
R
Site 54
Y627
R
M
G
I
L
N
S
Y
T
M
E
S
T
F
G
Site 55
S631
L
N
S
Y
T
M
E
S
T
F
G
G
S
T
L
Site 56
T632
N
S
Y
T
M
E
S
T
F
G
G
S
T
L
G
Site 57
T644
T
L
G
N
K
R
D
T
H
F
T
I
E
D
L
Site 58
T647
N
K
R
D
T
H
F
T
I
E
D
L
K
S
L
Site 59
S704
Q
D
V
D
L
E
G
S
W
S
D
I
S
L
S
Site 60
S706
V
D
L
E
G
S
W
S
D
I
S
L
S
D
I
Site 61
S709
E
G
S
W
S
D
I
S
L
S
D
I
E
S
S
Site 62
S711
S
W
S
D
I
S
L
S
D
I
E
S
S
T
S
Site 63
S715
I
S
L
S
D
I
E
S
S
T
S
G
S
D
S
Site 64
S716
S
L
S
D
I
E
S
S
T
S
G
S
D
S
S
Site 65
S718
S
D
I
E
S
S
T
S
G
S
D
S
S
L
S
Site 66
S720
I
E
S
S
T
S
G
S
D
S
S
L
S
D
G
Site 67
S722
S
S
T
S
G
S
D
S
S
L
S
D
G
L
P
Site 68
S723
S
T
S
G
S
D
S
S
L
S
D
G
L
P
V
Site 69
S725
S
G
S
D
S
S
L
S
D
G
L
P
V
H
L
Site 70
T740
A
N
I
A
D
E
L
T
Q
K
K
K
M
F
K
Site 71
S753
F
K
K
K
K
K
K
S
L
Q
T
R
K
Q
R
Site 72
Y764
R
K
Q
R
N
E
Q
Y
Q
K
K
N
L
M
Q
Site 73
T776
L
M
Q
K
L
K
L
T
E
D
T
S
E
K
A
Site 74
S780
L
K
L
T
E
D
T
S
E
K
A
G
F
A
S
Site 75
T788
E
K
A
G
F
A
S
T
L
Q
K
Q
P
T
F
Site 76
T794
S
T
L
Q
K
Q
P
T
F
F
K
N
S
E
N
Site 77
S799
Q
P
T
F
F
K
N
S
E
N
S
S
F
L
P
Site 78
S803
F
K
N
S
E
N
S
S
F
L
P
M
K
N
E
Site 79
T826
L
N
R
R
D
K
D
T
P
L
D
P
S
M
A
Site 80
T852
Q
N
K
K
P
G
F
T
V
S
C
S
P
K
R
Site 81
S854
K
K
P
G
F
T
V
S
C
S
P
K
R
T
I
Site 82
S856
P
G
F
T
V
S
C
S
P
K
R
T
I
N
S
Site 83
T860
V
S
C
S
P
K
R
T
I
N
S
S
Q
E
P
Site 84
S864
P
K
R
T
I
N
S
S
Q
E
P
A
P
G
M
Site 85
S878
M
K
P
N
W
P
R
S
R
Y
P
A
T
K
R
Site 86
Y880
P
N
W
P
R
S
R
Y
P
A
T
K
R
G
C
Site 87
T883
P
R
S
R
Y
P
A
T
K
R
G
C
A
A
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation