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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF468
Full Name:
Zinc finger protein 468
Alias:
Type:
Mass (Da):
60573
Number AA:
522
UniProt ID:
Q5VIY5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
R
D
V
A
I
E
F
S
Q
E
E
W
K
C
L
Site 2
Y33
D
P
A
Q
R
T
L
Y
R
D
V
M
L
E
N
Site 3
Y41
R
D
V
M
L
E
N
Y
R
N
L
V
S
L
D
Site 4
S46
E
N
Y
R
N
L
V
S
L
D
I
S
S
K
C
Site 5
T57
S
S
K
C
M
L
K
T
L
S
S
T
G
Q
G
Site 6
S59
K
C
M
L
K
T
L
S
S
T
G
Q
G
N
T
Site 7
T114
N
G
H
A
A
P
M
T
E
I
K
E
L
A
G
Site 8
S122
E
I
K
E
L
A
G
S
T
G
Q
H
D
Q
R
Site 9
S143
I
K
D
Q
L
G
S
S
F
H
L
H
L
P
E
Site 10
S167
I
G
N
Q
V
E
K
S
I
N
N
A
S
S
V
Site 11
S172
E
K
S
I
N
N
A
S
S
V
S
T
S
Q
R
Site 12
S173
K
S
I
N
N
A
S
S
V
S
T
S
Q
R
I
Site 13
T176
N
N
A
S
S
V
S
T
S
Q
R
I
C
C
R
Site 14
S177
N
A
S
S
V
S
T
S
Q
R
I
C
C
R
P
Site 15
T186
R
I
C
C
R
P
K
T
H
I
S
N
K
Y
G
Site 16
Y192
K
T
H
I
S
N
K
Y
G
N
N
S
L
H
S
Site 17
S196
S
N
K
Y
G
N
N
S
L
H
S
S
L
L
T
Site 18
S200
G
N
N
S
L
H
S
S
L
L
T
Q
K
W
E
Site 19
T203
S
L
H
S
S
L
L
T
Q
K
W
E
V
H
M
Site 20
S214
E
V
H
M
R
E
K
S
F
E
C
I
Q
S
F
Site 21
S227
S
F
K
S
F
N
C
S
S
L
L
K
K
H
Q
Site 22
S228
F
K
S
F
N
C
S
S
L
L
K
K
H
Q
I
Site 23
Y257
K
V
F
N
Q
K
R
Y
L
A
C
H
R
R
C
Site 24
T266
A
C
H
R
R
C
H
T
G
E
K
P
Y
K
C
Site 25
Y271
C
H
T
G
E
K
P
Y
K
C
N
E
C
G
K
Site 26
S284
G
K
T
F
G
H
N
S
S
L
F
I
H
K
A
Site 27
S285
K
T
F
G
H
N
S
S
L
F
I
H
K
A
L
Site 28
Y299
L
H
T
G
E
K
P
Y
E
C
E
E
C
D
K
Site 29
S312
D
K
V
F
S
R
K
S
H
L
E
R
H
K
R
Site 30
T322
E
R
H
K
R
I
H
T
G
E
K
P
Y
K
C
Site 31
Y338
V
C
D
E
A
F
A
Y
N
S
Y
L
A
K
H
Site 32
Y355
L
H
T
G
E
K
P
Y
T
C
N
E
C
G
K
Site 33
S368
G
K
V
F
N
R
L
S
T
L
A
R
H
H
R
Site 34
T369
K
V
F
N
R
L
S
T
L
A
R
H
H
R
L
Site 35
T378
A
R
H
H
R
L
H
T
G
E
K
P
Y
K
C
Site 36
S396
D
K
V
F
S
R
K
S
H
L
E
R
H
R
R
Site 37
S406
E
R
H
R
R
I
H
S
G
E
K
P
Y
K
C
Site 38
S424
C
K
V
F
S
R
K
S
N
L
E
R
H
R
R
Site 39
T434
E
R
H
R
R
I
H
T
G
E
K
P
Y
K
C
Site 40
S452
D
K
A
F
Q
R
D
S
H
L
A
Q
H
Q
R
Site 41
T462
A
Q
H
Q
R
V
H
T
G
E
K
P
Y
K
C
Site 42
Y467
V
H
T
G
E
K
P
Y
K
C
N
E
C
G
K
Site 43
T475
K
C
N
E
C
G
K
T
F
G
Q
T
S
S
L
Site 44
S480
G
K
T
F
G
Q
T
S
S
L
I
I
H
R
R
Site 45
S481
K
T
F
G
Q
T
S
S
L
I
I
H
R
R
L
Site 46
T490
I
I
H
R
R
L
H
T
G
E
K
P
Y
K
C
Site 47
Y495
L
H
T
G
E
K
P
Y
K
C
N
E
C
G
K
Site 48
T503
K
C
N
E
C
G
K
T
F
S
Q
M
S
S
L
Site 49
S505
N
E
C
G
K
T
F
S
Q
M
S
S
L
V
Y
Site 50
S508
G
K
T
F
S
Q
M
S
S
L
V
Y
H
H
R
Site 51
S509
K
T
F
S
Q
M
S
S
L
V
Y
H
H
R
L
Site 52
Y512
S
Q
M
S
S
L
V
Y
H
H
R
L
H
S
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation