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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM40A
Full Name:
Protein FAM40A
Alias:
FA40A; KIAA1761
Type:
Uncharacterized protein
Mass (Da):
95576
Number AA:
837
UniProt ID:
Q5VSL9
International Prot ID:
IPI00549766
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S59
N
R
N
Q
R
K
D
S
E
G
Y
S
E
S
P
Site 2
Y62
Q
R
K
D
S
E
G
Y
S
E
S
P
D
L
E
Site 3
S63
R
K
D
S
E
G
Y
S
E
S
P
D
L
E
F
Site 4
S65
D
S
E
G
Y
S
E
S
P
D
L
E
F
E
Y
Site 5
Y72
S
P
D
L
E
F
E
Y
A
D
T
D
K
W
A
Site 6
T75
L
E
F
E
Y
A
D
T
D
K
W
A
A
E
L
Site 7
S83
D
K
W
A
A
E
L
S
E
L
Y
S
Y
T
E
Site 8
S87
A
E
L
S
E
L
Y
S
Y
T
E
G
P
E
F
Site 9
Y88
E
L
S
E
L
Y
S
Y
T
E
G
P
E
F
L
Site 10
T89
L
S
E
L
Y
S
Y
T
E
G
P
E
F
L
M
Site 11
S161
G
T
F
G
E
C
S
S
E
A
E
V
Q
S
W
Site 12
S200
I
D
N
S
A
A
C
S
S
A
V
R
K
P
A
Site 13
S201
D
N
S
A
A
C
S
S
A
V
R
K
P
A
I
Site 14
T247
E
W
R
T
M
R
Q
T
F
R
A
E
L
G
S
Site 15
S254
T
F
R
A
E
L
G
S
P
L
Y
N
N
E
P
Site 16
Y257
A
E
L
G
S
P
L
Y
N
N
E
P
F
A
I
Site 17
S306
G
G
F
E
E
L
Q
S
M
K
A
E
K
R
S
Site 18
S313
S
M
K
A
E
K
R
S
I
L
G
L
P
P
L
Site 19
S324
L
P
P
L
P
E
D
S
I
K
V
I
R
N
M
Site 20
S335
I
R
N
M
R
A
A
S
P
P
A
S
A
S
D
Site 21
S339
R
A
A
S
P
P
A
S
A
S
D
L
I
E
Q
Site 22
S341
A
S
P
P
A
S
A
S
D
L
I
E
Q
Q
Q
Site 23
Y373
A
F
N
E
R
D
P
Y
K
A
D
D
S
R
E
Site 24
S378
D
P
Y
K
A
D
D
S
R
E
E
E
E
E
N
Site 25
S390
E
E
N
D
D
D
N
S
L
E
G
E
T
F
P
Site 26
T413
P
P
L
Q
H
P
Q
T
D
R
L
T
C
P
K
Site 27
T417
H
P
Q
T
D
R
L
T
C
P
K
G
L
P
W
Site 28
S439
D
I
E
M
F
L
E
S
S
R
S
K
F
I
G
Site 29
S440
I
E
M
F
L
E
S
S
R
S
K
F
I
G
Y
Site 30
S442
M
F
L
E
S
S
R
S
K
F
I
G
Y
T
L
Site 31
Y447
S
R
S
K
F
I
G
Y
T
L
G
S
D
T
N
Site 32
T448
R
S
K
F
I
G
Y
T
L
G
S
D
T
N
T
Site 33
T455
T
L
G
S
D
T
N
T
V
V
G
L
P
R
P
Site 34
S466
L
P
R
P
I
H
E
S
I
K
T
L
K
Q
H
Site 35
T469
P
I
H
E
S
I
K
T
L
K
Q
H
K
Y
T
Site 36
Y475
K
T
L
K
Q
H
K
Y
T
S
I
A
E
V
Q
Site 37
Y489
Q
A
Q
M
E
E
E
Y
L
R
S
P
L
S
G
Site 38
S492
M
E
E
E
Y
L
R
S
P
L
S
G
G
E
E
Site 39
S495
E
Y
L
R
S
P
L
S
G
G
E
E
E
V
E
Site 40
T539
A
P
T
S
K
A
K
T
D
S
I
N
I
L
A
Site 41
T555
V
L
P
E
E
M
P
T
T
V
L
Q
S
M
K
Site 42
T556
L
P
E
E
M
P
T
T
V
L
Q
S
M
K
L
Site 43
S560
M
P
T
T
V
L
Q
S
M
K
L
G
V
D
V
Site 44
S630
S
Y
I
T
A
K
N
S
I
S
V
L
D
Y
P
Site 45
S632
I
T
A
K
N
S
I
S
V
L
D
Y
P
H
C
Site 46
Y636
N
S
I
S
V
L
D
Y
P
H
C
V
V
H
E
Site 47
S651
L
P
E
L
T
A
E
S
L
E
A
G
D
S
N
Site 48
Y723
L
L
K
V
Q
T
K
Y
L
G
R
Q
W
R
K
Site 49
S731
L
G
R
Q
W
R
K
S
N
M
K
T
M
S
A
Site 50
T735
W
R
K
S
N
M
K
T
M
S
A
I
Y
Q
K
Site 51
Y740
M
K
T
M
S
A
I
Y
Q
K
V
R
H
R
L
Site 52
Y753
R
L
N
D
D
W
A
Y
G
N
D
L
D
A
R
Site 53
Y783
E
R
F
N
A
R
R
Y
D
R
A
H
S
N
P
Site 54
S788
R
R
Y
D
R
A
H
S
N
P
D
F
L
P
V
Site 55
S801
P
V
D
N
C
L
Q
S
V
L
G
Q
R
V
D
Site 56
Y817
P
E
D
F
Q
M
N
Y
D
L
W
L
E
R
E
Site 57
S831
E
V
F
S
K
P
I
S
W
E
E
L
L
Q
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation