KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
FAM108B1
Full Name:
Abhydrolase domain-containing protein FAM108B1
Alias:
abhydrolase domain-containing; C9orf77; CGI-67; F108B; family with sequence similarity 108, B1; family with sequence similarity 108, member B1; RP11-409O11.2
Type:
Hydrolase; EC 3.-.-.-
Mass (Da):
32196
Number AA:
288
UniProt ID:
Q5VST6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0016787
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T34
A
F
L
P
P
D
P
T
Y
T
L
M
C
D
E
Site 2
Y35
F
L
P
P
D
P
T
Y
T
L
M
C
D
E
S
Site 3
T36
L
P
P
D
P
T
Y
T
L
M
C
D
E
S
G
Site 4
T47
D
E
S
G
S
R
W
T
L
H
L
S
E
R
A
Site 5
Y58
S
E
R
A
D
W
Q
Y
S
S
R
E
K
D
A
Site 6
S59
E
R
A
D
W
Q
Y
S
S
R
E
K
D
A
I
Site 7
S60
R
A
D
W
Q
Y
S
S
R
E
K
D
A
I
E
Site 8
T71
D
A
I
E
C
F
M
T
R
T
S
K
G
N
R
Site 9
Y92
R
C
S
P
N
A
K
Y
T
L
L
F
S
H
G
Site 10
T93
C
S
P
N
A
K
Y
T
L
L
F
S
H
G
N
Site 11
Y125
I
N
C
N
I
F
S
Y
D
Y
S
G
Y
G
A
Site 12
Y127
C
N
I
F
S
Y
D
Y
S
G
Y
G
A
S
S
Site 13
S128
N
I
F
S
Y
D
Y
S
G
Y
G
A
S
S
G
Site 14
Y130
F
S
Y
D
Y
S
G
Y
G
A
S
S
G
K
P
Site 15
S134
Y
S
G
Y
G
A
S
S
G
K
P
T
E
K
N
Site 16
T138
G
A
S
S
G
K
P
T
E
K
N
L
Y
A
D
Site 17
Y143
K
P
T
E
K
N
L
Y
A
D
I
E
A
A
W
Site 18
Y157
W
L
A
L
R
T
R
Y
G
I
R
P
E
N
V
Site 19
Y270
G
H
N
D
V
E
L
Y
G
Q
Y
L
E
R
L
Site 20
Y273
D
V
E
L
Y
G
Q
Y
L
E
R
L
K
Q
F
Site 21
S282
E
R
L
K
Q
F
V
S
Q
E
L
V
N
L
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation