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Updated November 2019
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Protein Info
Short Name:
RPRD2
Full Name:
Regulation of nuclear pre-mRNA domain-containing protein 2
Alias:
FLJ32145; HSPC099; K0460; KIAA0460; regulation of nuclear pre-mRNA domain containing 2
Type:
Unknown function
Mass (Da):
156020
Number AA:
1461
UniProt ID:
Q5VT52
International Prot ID:
IPI00384541
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
A
A
G
G
G
G
G
S
S
K
A
S
S
S
S
Site 2
S10
A
G
G
G
G
G
S
S
K
A
S
S
S
S
A
Site 3
S13
G
G
G
S
S
K
A
S
S
S
S
A
S
S
A
Site 4
S14
G
G
S
S
K
A
S
S
S
S
A
S
S
A
G
Site 5
S15
G
S
S
K
A
S
S
S
S
A
S
S
A
G
A
Site 6
S16
S
S
K
A
S
S
S
S
A
S
S
A
G
A
L
Site 7
S18
K
A
S
S
S
S
A
S
S
A
G
A
L
E
S
Site 8
S19
A
S
S
S
S
A
S
S
A
G
A
L
E
S
S
Site 9
S26
S
A
G
A
L
E
S
S
L
D
R
K
F
Q
S
Site 10
S33
S
L
D
R
K
F
Q
S
V
T
N
T
M
E
S
Site 11
T37
K
F
Q
S
V
T
N
T
M
E
S
I
Q
G
L
Site 12
S40
S
V
T
N
T
M
E
S
I
Q
G
L
S
S
W
Site 13
S46
E
S
I
Q
G
L
S
S
W
C
I
E
N
K
K
Site 14
Y71
K
W
L
R
R
S
A
Y
P
H
R
L
N
L
F
Site 15
Y79
P
H
R
L
N
L
F
Y
L
A
N
D
V
I
Q
Site 16
S99
N
A
I
I
F
R
E
S
F
A
D
V
L
P
E
Site 17
S115
A
A
L
V
K
D
P
S
V
S
K
S
V
E
R
Site 18
S117
L
V
K
D
P
S
V
S
K
S
V
E
R
I
F
Site 19
S119
K
D
P
S
V
S
K
S
V
E
R
I
F
K
I
Site 20
Y133
I
W
E
D
R
N
V
Y
P
E
E
M
I
V
A
Site 21
S146
V
A
L
R
E
A
L
S
T
T
F
K
T
Q
K
Site 22
T147
A
L
R
E
A
L
S
T
T
F
K
T
Q
K
Q
Site 23
T148
L
R
E
A
L
S
T
T
F
K
T
Q
K
Q
L
Site 24
S170
P
N
K
Q
W
K
K
S
Q
T
S
T
N
P
K
Site 25
T174
W
K
K
S
Q
T
S
T
N
P
K
A
A
L
K
Site 26
Y200
L
I
E
E
L
L
L
Y
K
R
S
E
D
Q
I
Site 27
S203
E
L
L
L
Y
K
R
S
E
D
Q
I
E
L
K
Site 28
S215
E
L
K
E
K
Q
L
S
T
M
R
V
D
V
C
Site 29
T216
L
K
E
K
Q
L
S
T
M
R
V
D
V
C
S
Site 30
T234
L
K
C
L
K
D
K
T
G
G
K
K
F
S
K
Site 31
S240
K
T
G
G
K
K
F
S
K
E
F
E
E
A
S
Site 32
S248
K
E
F
E
E
A
S
S
K
L
E
E
F
V
N
Site 33
Y278
L
E
N
A
G
I
F
Y
E
A
Q
Y
K
E
V
Site 34
T294
V
V
A
N
A
Y
K
T
F
A
N
R
V
N
N
Site 35
S311
K
K
L
D
Q
L
K
S
T
L
P
D
P
E
E
Site 36
S319
T
L
P
D
P
E
E
S
P
V
P
S
P
S
M
Site 37
S323
P
E
E
S
P
V
P
S
P
S
M
D
A
P
S
Site 38
S325
E
S
P
V
P
S
P
S
M
D
A
P
S
P
T
Site 39
S330
S
P
S
M
D
A
P
S
P
T
G
S
E
S
P
Site 40
T332
S
M
D
A
P
S
P
T
G
S
E
S
P
F
Q
Site 41
S334
D
A
P
S
P
T
G
S
E
S
P
F
Q
G
M
Site 42
S336
P
S
P
T
G
S
E
S
P
F
Q
G
M
G
G
Site 43
S346
Q
G
M
G
G
E
E
S
Q
S
P
T
M
E
S
Site 44
S348
M
G
G
E
E
S
Q
S
P
T
M
E
S
E
K
Site 45
T350
G
E
E
S
Q
S
P
T
M
E
S
E
K
S
A
Site 46
S353
S
Q
S
P
T
M
E
S
E
K
S
A
T
P
E
Site 47
S356
P
T
M
E
S
E
K
S
A
T
P
E
P
V
T
Site 48
T358
M
E
S
E
K
S
A
T
P
E
P
V
T
D
N
Site 49
T363
S
A
T
P
E
P
V
T
D
N
R
D
V
E
D
Site 50
S374
D
V
E
D
M
E
L
S
D
V
E
D
D
G
S
Site 51
S381
S
D
V
E
D
D
G
S
K
I
I
V
E
D
R
Site 52
S396
K
E
K
P
A
E
K
S
A
V
S
T
S
V
P
Site 53
S399
P
A
E
K
S
A
V
S
T
S
V
P
T
K
P
Site 54
T400
A
E
K
S
A
V
S
T
S
V
P
T
K
P
T
Site 55
S401
E
K
S
A
V
S
T
S
V
P
T
K
P
T
E
Site 56
S411
T
K
P
T
E
N
I
S
K
A
S
S
C
T
P
Site 57
S415
E
N
I
S
K
A
S
S
C
T
P
V
P
V
T
Site 58
S436
L
P
K
P
V
N
T
S
L
S
P
S
P
A
L
Site 59
S440
V
N
T
S
L
S
P
S
P
A
L
A
L
P
N
Site 60
S473
V
M
K
N
T
G
V
S
P
A
S
R
P
S
P
Site 61
S476
N
T
G
V
S
P
A
S
R
P
S
P
G
T
P
Site 62
S479
V
S
P
A
S
R
P
S
P
G
T
P
T
S
P
Site 63
T482
A
S
R
P
S
P
G
T
P
T
S
P
S
N
L
Site 64
T484
R
P
S
P
G
T
P
T
S
P
S
N
L
T
S
Site 65
S485
P
S
P
G
T
P
T
S
P
S
N
L
T
S
G
Site 66
S487
P
G
T
P
T
S
P
S
N
L
T
S
G
L
K
Site 67
T490
P
T
S
P
S
N
L
T
S
G
L
K
T
P
A
Site 68
S491
T
S
P
S
N
L
T
S
G
L
K
T
P
A
P
Site 69
T495
N
L
T
S
G
L
K
T
P
A
P
A
T
T
T
Site 70
S512
N
P
L
A
N
I
L
S
K
V
E
I
T
P
E
Site 71
T517
I
L
S
K
V
E
I
T
P
E
S
I
L
S
A
Site 72
S523
I
T
P
E
S
I
L
S
A
L
S
K
T
Q
T
Site 73
S526
E
S
I
L
S
A
L
S
K
T
Q
T
Q
S
A
Site 74
T528
I
L
S
A
L
S
K
T
Q
T
Q
S
A
P
A
Site 75
T530
S
A
L
S
K
T
Q
T
Q
S
A
P
A
L
Q
Site 76
T547
S
S
L
L
Q
S
V
T
G
N
P
V
P
A
S
Site 77
S554
T
G
N
P
V
P
A
S
E
A
A
S
Q
S
T
Site 78
S558
V
P
A
S
E
A
A
S
Q
S
T
S
A
S
P
Site 79
S560
A
S
E
A
A
S
Q
S
T
S
A
S
P
A
N
Site 80
S562
E
A
A
S
Q
S
T
S
A
S
P
A
N
T
T
Site 81
S564
A
S
Q
S
T
S
A
S
P
A
N
T
T
V
S
Site 82
T568
T
S
A
S
P
A
N
T
T
V
S
T
I
K
G
Site 83
S571
S
P
A
N
T
T
V
S
T
I
K
G
R
N
L
Site 84
S581
K
G
R
N
L
P
S
S
A
Q
P
F
I
P
K
Site 85
S589
A
Q
P
F
I
P
K
S
F
N
Y
S
P
N
S
Site 86
Y592
F
I
P
K
S
F
N
Y
S
P
N
S
S
T
S
Site 87
S593
I
P
K
S
F
N
Y
S
P
N
S
S
T
S
E
Site 88
S596
S
F
N
Y
S
P
N
S
S
T
S
E
V
S
S
Site 89
S597
F
N
Y
S
P
N
S
S
T
S
E
V
S
S
T
Site 90
T598
N
Y
S
P
N
S
S
T
S
E
V
S
S
T
S
Site 91
S599
Y
S
P
N
S
S
T
S
E
V
S
S
T
S
A
Site 92
S602
N
S
S
T
S
E
V
S
S
T
S
A
S
K
A
Site 93
S603
S
S
T
S
E
V
S
S
T
S
A
S
K
A
S
Site 94
T604
S
T
S
E
V
S
S
T
S
A
S
K
A
S
I
Site 95
S605
T
S
E
V
S
S
T
S
A
S
K
A
S
I
G
Site 96
S607
E
V
S
S
T
S
A
S
K
A
S
I
G
Q
S
Site 97
S610
S
T
S
A
S
K
A
S
I
G
Q
S
P
G
L
Site 98
S614
S
K
A
S
I
G
Q
S
P
G
L
P
S
T
T
Site 99
S619
G
Q
S
P
G
L
P
S
T
T
F
K
L
P
S
Site 100
T620
Q
S
P
G
L
P
S
T
T
F
K
L
P
S
N
Site 101
T621
S
P
G
L
P
S
T
T
F
K
L
P
S
N
S
Site 102
S626
S
T
T
F
K
L
P
S
N
S
L
G
F
T
A
Site 103
S628
T
F
K
L
P
S
N
S
L
G
F
T
A
T
H
Site 104
T632
P
S
N
S
L
G
F
T
A
T
H
N
T
S
P
Site 105
T634
N
S
L
G
F
T
A
T
H
N
T
S
P
A
A
Site 106
S638
F
T
A
T
H
N
T
S
P
A
A
P
P
T
E
Site 107
T644
T
S
P
A
A
P
P
T
E
V
T
I
C
Q
S
Site 108
S651
T
E
V
T
I
C
Q
S
S
E
V
S
K
P
K
Site 109
S655
I
C
Q
S
S
E
V
S
K
P
K
L
E
S
E
Site 110
S661
V
S
K
P
K
L
E
S
E
S
T
S
P
S
L
Site 111
S663
K
P
K
L
E
S
E
S
T
S
P
S
L
E
M
Site 112
T664
P
K
L
E
S
E
S
T
S
P
S
L
E
M
K
Site 113
S665
K
L
E
S
E
S
T
S
P
S
L
E
M
K
I
Site 114
S667
E
S
E
S
T
S
P
S
L
E
M
K
I
H
N
Site 115
S697
P
I
L
S
S
L
G
S
S
A
P
S
E
S
H
Site 116
S698
I
L
S
S
L
G
S
S
A
P
S
E
S
H
P
Site 117
S701
S
L
G
S
S
A
P
S
E
S
H
P
S
D
F
Site 118
S703
G
S
S
A
P
S
E
S
H
P
S
D
F
Q
R
Site 119
S706
A
P
S
E
S
H
P
S
D
F
Q
R
G
P
T
Site 120
T713
S
D
F
Q
R
G
P
T
S
T
S
I
D
N
I
Site 121
S714
D
F
Q
R
G
P
T
S
T
S
I
D
N
I
D
Site 122
T715
F
Q
R
G
P
T
S
T
S
I
D
N
I
D
G
Site 123
T723
S
I
D
N
I
D
G
T
P
V
R
D
E
R
S
Site 124
S730
T
P
V
R
D
E
R
S
G
T
P
T
Q
D
E
Site 125
T732
V
R
D
E
R
S
G
T
P
T
Q
D
E
M
M
Site 126
T734
D
E
R
S
G
T
P
T
Q
D
E
M
M
D
K
Site 127
S744
E
M
M
D
K
P
T
S
S
S
V
D
T
M
S
Site 128
S745
M
M
D
K
P
T
S
S
S
V
D
T
M
S
L
Site 129
S746
M
D
K
P
T
S
S
S
V
D
T
M
S
L
L
Site 130
T749
P
T
S
S
S
V
D
T
M
S
L
L
S
K
I
Site 131
S758
S
L
L
S
K
I
I
S
P
G
S
S
T
P
S
Site 132
S761
S
K
I
I
S
P
G
S
S
T
P
S
S
T
R
Site 133
S762
K
I
I
S
P
G
S
S
T
P
S
S
T
R
S
Site 134
T763
I
I
S
P
G
S
S
T
P
S
S
T
R
S
P
Site 135
S765
S
P
G
S
S
T
P
S
S
T
R
S
P
P
P
Site 136
S766
P
G
S
S
T
P
S
S
T
R
S
P
P
P
G
Site 137
T767
G
S
S
T
P
S
S
T
R
S
P
P
P
G
R
Site 138
S769
S
T
P
S
S
T
R
S
P
P
P
G
R
D
E
Site 139
S777
P
P
P
G
R
D
E
S
Y
P
R
E
L
S
N
Site 140
Y778
P
P
G
R
D
E
S
Y
P
R
E
L
S
N
S
Site 141
S783
E
S
Y
P
R
E
L
S
N
S
V
S
T
Y
R
Site 142
S785
Y
P
R
E
L
S
N
S
V
S
T
Y
R
P
F
Site 143
S787
R
E
L
S
N
S
V
S
T
Y
R
P
F
G
L
Site 144
T788
E
L
S
N
S
V
S
T
Y
R
P
F
G
L
G
Site 145
Y789
L
S
N
S
V
S
T
Y
R
P
F
G
L
G
S
Site 146
S796
Y
R
P
F
G
L
G
S
E
S
P
Y
K
Q
P
Site 147
S798
P
F
G
L
G
S
E
S
P
Y
K
Q
P
S
D
Site 148
Y800
G
L
G
S
E
S
P
Y
K
Q
P
S
D
G
M
Site 149
S804
E
S
P
Y
K
Q
P
S
D
G
M
E
R
P
S
Site 150
S811
S
D
G
M
E
R
P
S
S
L
M
D
S
S
Q
Site 151
S812
D
G
M
E
R
P
S
S
L
M
D
S
S
Q
E
Site 152
S816
R
P
S
S
L
M
D
S
S
Q
E
K
F
Y
P
Site 153
S817
P
S
S
L
M
D
S
S
Q
E
K
F
Y
P
D
Site 154
Y822
D
S
S
Q
E
K
F
Y
P
D
T
S
F
Q
E
Site 155
T825
Q
E
K
F
Y
P
D
T
S
F
Q
E
D
E
D
Site 156
S826
E
K
F
Y
P
D
T
S
F
Q
E
D
E
D
Y
Site 157
Y833
S
F
Q
E
D
E
D
Y
R
D
F
E
Y
S
G
Site 158
Y838
E
D
Y
R
D
F
E
Y
S
G
P
P
P
S
A
Site 159
S839
D
Y
R
D
F
E
Y
S
G
P
P
P
S
A
M
Site 160
S844
E
Y
S
G
P
P
P
S
A
M
M
N
L
E
K
Site 161
S856
L
E
K
K
P
A
K
S
I
L
K
S
S
K
L
Site 162
S860
P
A
K
S
I
L
K
S
S
K
L
S
D
T
T
Site 163
S864
I
L
K
S
S
K
L
S
D
T
T
E
Y
Q
P
Site 164
T866
K
S
S
K
L
S
D
T
T
E
Y
Q
P
I
L
Site 165
T867
S
S
K
L
S
D
T
T
E
Y
Q
P
I
L
S
Site 166
Y869
K
L
S
D
T
T
E
Y
Q
P
I
L
S
S
Y
Site 167
S874
T
E
Y
Q
P
I
L
S
S
Y
S
H
R
A
Q
Site 168
S875
E
Y
Q
P
I
L
S
S
Y
S
H
R
A
Q
E
Site 169
S877
Q
P
I
L
S
S
Y
S
H
R
A
Q
E
F
G
Site 170
S887
A
Q
E
F
G
V
K
S
A
F
P
P
S
V
R
Site 171
S899
S
V
R
A
L
L
D
S
S
E
N
C
D
R
L
Site 172
S900
V
R
A
L
L
D
S
S
E
N
C
D
R
L
S
Site 173
S907
S
E
N
C
D
R
L
S
S
S
P
G
L
F
G
Site 174
S908
E
N
C
D
R
L
S
S
S
P
G
L
F
G
A
Site 175
S909
N
C
D
R
L
S
S
S
P
G
L
F
G
A
F
Site 176
S917
P
G
L
F
G
A
F
S
V
R
G
N
E
P
G
Site 177
S925
V
R
G
N
E
P
G
S
D
R
S
P
S
P
S
Site 178
S928
N
E
P
G
S
D
R
S
P
S
P
S
K
N
D
Site 179
S930
P
G
S
D
R
S
P
S
P
S
K
N
D
S
F
Site 180
S932
S
D
R
S
P
S
P
S
K
N
D
S
F
F
T
Site 181
S936
P
S
P
S
K
N
D
S
F
F
T
P
D
S
N
Site 182
T939
S
K
N
D
S
F
F
T
P
D
S
N
H
N
S
Site 183
S942
D
S
F
F
T
P
D
S
N
H
N
S
L
S
Q
Site 184
S946
T
P
D
S
N
H
N
S
L
S
Q
S
T
T
G
Site 185
S948
D
S
N
H
N
S
L
S
Q
S
T
T
G
H
L
Site 186
S950
N
H
N
S
L
S
Q
S
T
T
G
H
L
S
L
Site 187
T952
N
S
L
S
Q
S
T
T
G
H
L
S
L
P
Q
Site 188
S956
Q
S
T
T
G
H
L
S
L
P
Q
K
Q
Y
P
Site 189
Y962
L
S
L
P
Q
K
Q
Y
P
D
S
P
H
P
V
Site 190
S965
P
Q
K
Q
Y
P
D
S
P
H
P
V
P
H
R
Site 191
S973
P
H
P
V
P
H
R
S
L
F
S
P
Q
N
T
Site 192
S976
V
P
H
R
S
L
F
S
P
Q
N
T
L
A
A
Site 193
T980
S
L
F
S
P
Q
N
T
L
A
A
P
T
G
H
Site 194
S991
P
T
G
H
P
P
T
S
G
V
E
K
V
L
A
Site 195
T1006
S
T
I
S
T
T
S
T
I
E
F
K
N
M
L
Site 196
S1017
K
N
M
L
K
N
A
S
R
K
P
S
D
D
K
Site 197
S1021
K
N
A
S
R
K
P
S
D
D
K
H
F
G
Q
Site 198
S1031
K
H
F
G
Q
A
P
S
K
G
T
P
S
D
G
Site 199
T1034
G
Q
A
P
S
K
G
T
P
S
D
G
V
S
L
Site 200
S1036
A
P
S
K
G
T
P
S
D
G
V
S
L
S
N
Site 201
S1040
G
T
P
S
D
G
V
S
L
S
N
L
T
Q
P
Site 202
S1042
P
S
D
G
V
S
L
S
N
L
T
Q
P
S
L
Site 203
S1048
L
S
N
L
T
Q
P
S
L
T
A
T
D
Q
Q
Site 204
T1052
T
Q
P
S
L
T
A
T
D
Q
Q
Q
Q
E
E
Site 205
T1065
E
E
H
Y
R
I
E
T
R
V
S
S
S
C
L
Site 206
S1068
Y
R
I
E
T
R
V
S
S
S
C
L
D
L
P
Site 207
S1069
R
I
E
T
R
V
S
S
S
C
L
D
L
P
D
Site 208
S1070
I
E
T
R
V
S
S
S
C
L
D
L
P
D
S
Site 209
S1077
S
C
L
D
L
P
D
S
T
E
E
K
G
A
P
Site 210
T1078
C
L
D
L
P
D
S
T
E
E
K
G
A
P
I
Site 211
Y1090
A
P
I
E
T
L
G
Y
H
S
A
S
N
R
R
Site 212
S1094
T
L
G
Y
H
S
A
S
N
R
R
M
S
G
E
Site 213
S1099
S
A
S
N
R
R
M
S
G
E
P
I
Q
T
V
Site 214
T1105
M
S
G
E
P
I
Q
T
V
E
S
I
R
V
P
Site 215
S1108
E
P
I
Q
T
V
E
S
I
R
V
P
G
K
G
Site 216
S1124
R
G
H
G
R
E
A
S
R
V
G
W
F
D
L
Site 217
S1132
R
V
G
W
F
D
L
S
T
S
G
S
S
F
D
Site 218
T1133
V
G
W
F
D
L
S
T
S
G
S
S
F
D
N
Site 219
S1134
G
W
F
D
L
S
T
S
G
S
S
F
D
N
G
Site 220
S1136
F
D
L
S
T
S
G
S
S
F
D
N
G
P
S
Site 221
S1137
D
L
S
T
S
G
S
S
F
D
N
G
P
S
S
Site 222
S1143
S
S
F
D
N
G
P
S
S
A
S
E
L
A
S
Site 223
S1144
S
F
D
N
G
P
S
S
A
S
E
L
A
S
L
Site 224
S1146
D
N
G
P
S
S
A
S
E
L
A
S
L
G
G
Site 225
S1150
S
S
A
S
E
L
A
S
L
G
G
G
G
S
G
Site 226
T1160
G
G
G
S
G
G
L
T
G
F
K
T
A
P
Y
Site 227
T1164
G
G
L
T
G
F
K
T
A
P
Y
K
E
R
A
Site 228
Y1167
T
G
F
K
T
A
P
Y
K
E
R
A
P
Q
F
Site 229
S1177
R
A
P
Q
F
Q
E
S
V
G
S
F
R
S
N
Site 230
S1180
Q
F
Q
E
S
V
G
S
F
R
S
N
S
F
N
Site 231
S1183
E
S
V
G
S
F
R
S
N
S
F
N
S
T
F
Site 232
S1185
V
G
S
F
R
S
N
S
F
N
S
T
F
E
H
Site 233
T1189
R
S
N
S
F
N
S
T
F
E
H
H
L
P
P
Site 234
S1197
F
E
H
H
L
P
P
S
P
L
E
H
G
T
P
Site 235
T1203
P
S
P
L
E
H
G
T
P
F
Q
R
E
P
V
Site 236
S1214
R
E
P
V
G
P
S
S
A
P
P
V
P
P
K
Site 237
S1228
K
D
H
G
G
I
F
S
R
D
A
P
T
H
L
Site 238
T1233
I
F
S
R
D
A
P
T
H
L
P
S
V
D
L
Site 239
S1237
D
A
P
T
H
L
P
S
V
D
L
S
N
P
F
Site 240
S1241
H
L
P
S
V
D
L
S
N
P
F
T
K
E
A
Site 241
T1245
V
D
L
S
N
P
F
T
K
E
A
A
L
A
H
Site 242
S1263
P
P
P
P
G
E
H
S
G
I
P
F
P
T
P
Site 243
T1269
H
S
G
I
P
F
P
T
P
P
P
P
P
P
P
Site 244
S1280
P
P
P
P
G
E
H
S
S
S
G
G
S
G
V
Site 245
S1281
P
P
P
G
E
H
S
S
S
G
G
S
G
V
P
Site 246
S1282
P
P
G
E
H
S
S
S
G
G
S
G
V
P
F
Site 247
S1285
E
H
S
S
S
G
G
S
G
V
P
F
S
T
P
Site 248
S1290
G
G
S
G
V
P
F
S
T
P
P
P
P
P
P
Site 249
T1291
G
S
G
V
P
F
S
T
P
P
P
P
P
P
P
Site 250
S1302
P
P
P
P
V
D
H
S
G
V
V
P
F
P
A
Site 251
S1330
V
F
P
K
D
H
S
S
L
L
Q
G
T
L
A
Site 252
T1353
P
R
D
H
G
G
P
T
Q
R
D
L
N
G
P
Site 253
S1363
D
L
N
G
P
G
L
S
R
V
R
E
S
L
T
Site 254
S1368
G
L
S
R
V
R
E
S
L
T
L
P
S
H
S
Site 255
T1370
S
R
V
R
E
S
L
T
L
P
S
H
S
L
E
Site 256
S1373
R
E
S
L
T
L
P
S
H
S
L
E
H
L
G
Site 257
S1375
S
L
T
L
P
S
H
S
L
E
H
L
G
P
P
Site 258
S1391
G
G
G
G
G
G
G
S
N
S
S
S
G
P
P
Site 259
S1393
G
G
G
G
G
S
N
S
S
S
G
P
P
L
G
Site 260
S1394
G
G
G
G
S
N
S
S
S
G
P
P
L
G
P
Site 261
S1395
G
G
G
S
N
S
S
S
G
P
P
L
G
P
S
Site 262
S1402
S
G
P
P
L
G
P
S
H
R
D
T
I
S
R
Site 263
T1406
L
G
P
S
H
R
D
T
I
S
R
S
G
I
I
Site 264
S1408
P
S
H
R
D
T
I
S
R
S
G
I
I
L
R
Site 265
S1416
R
S
G
I
I
L
R
S
P
R
P
D
F
R
P
Site 266
S1429
R
P
R
E
P
F
L
S
R
D
P
F
H
S
L
Site 267
S1435
L
S
R
D
P
F
H
S
L
K
R
P
R
P
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation