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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRAMEF17
Full Name:
PRAME family member 17
Alias:
Type:
Mass (Da):
54769
Number AA:
474
UniProt ID:
Q5VTA0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
S
L
Q
S
P
S
R
L
L
E
L
Site 2
T72
P
L
G
S
L
M
K
T
P
H
L
E
T
L
Q
Site 3
S123
W
S
G
A
R
A
L
S
C
S
P
E
A
M
S
Site 4
S125
G
A
R
A
L
S
C
S
P
E
A
M
S
K
R
Site 5
S130
S
C
S
P
E
A
M
S
K
R
Q
T
V
E
D
Site 6
T134
E
A
M
S
K
R
Q
T
V
E
D
Y
P
R
T
Site 7
Y138
K
R
Q
T
V
E
D
Y
P
R
T
G
E
H
Q
Site 8
T141
T
V
E
D
Y
P
R
T
G
E
H
Q
P
L
K
Site 9
S158
I
D
L
C
Q
K
E
S
T
L
D
E
C
L
S
Site 10
T159
D
L
C
Q
K
E
S
T
L
D
E
C
L
S
Y
Site 11
S165
S
T
L
D
E
C
L
S
Y
L
C
R
W
I
H
Site 12
Y166
T
L
D
E
C
L
S
Y
L
C
R
W
I
H
Y
Site 13
Y188
C
C
N
K
V
Q
N
Y
S
M
P
T
S
S
F
Site 14
S189
C
N
K
V
Q
N
Y
S
M
P
T
S
S
F
R
Site 15
S193
Q
N
Y
S
M
P
T
S
S
F
R
N
L
L
K
Site 16
S194
N
Y
S
M
P
T
S
S
F
R
N
L
L
K
R
Site 17
Y203
R
N
L
L
K
R
V
Y
P
D
S
I
Q
E
L
Site 18
S206
L
K
R
V
Y
P
D
S
I
Q
E
L
E
I
K
Site 19
S217
L
E
I
K
R
K
C
S
L
N
K
T
G
K
F
Site 20
T221
R
K
C
S
L
N
K
T
G
K
F
A
P
Y
L
Site 21
Y227
K
T
G
K
F
A
P
Y
L
S
Q
M
S
N
L
Site 22
S229
G
K
F
A
P
Y
L
S
Q
M
S
N
L
R
K
Site 23
S232
A
P
Y
L
S
Q
M
S
N
L
R
K
L
F
L
Site 24
Y248
F
G
Y
D
D
E
L
Y
V
S
G
Q
Q
Q
F
Site 25
S250
Y
D
D
E
L
Y
V
S
G
Q
Q
Q
F
V
P
Site 26
Y273
L
Y
Y
P
Q
M
L
Y
I
R
K
I
S
N
I
Site 27
S278
M
L
Y
I
R
K
I
S
N
I
K
E
H
L
E
Site 28
S314
D
Q
D
M
E
C
L
S
Q
Y
P
S
L
S
Q
Site 29
Y316
D
M
E
C
L
S
Q
Y
P
S
L
S
Q
L
K
Site 30
S318
E
C
L
S
Q
Y
P
S
L
S
Q
L
K
E
L
Site 31
S320
L
S
Q
Y
P
S
L
S
Q
L
K
E
L
H
L
Site 32
T335
I
H
I
L
M
W
T
T
N
L
E
P
L
G
A
Site 33
S364
K
D
C
Q
I
Q
D
S
Q
L
R
V
L
L
P
Site 34
T380
L
S
R
C
S
Q
L
T
T
F
Y
F
R
G
N
Site 35
T381
S
R
C
S
Q
L
T
T
F
Y
F
R
G
N
E
Site 36
Y383
C
S
Q
L
T
T
F
Y
F
R
G
N
E
T
S
Site 37
S390
Y
F
R
G
N
E
T
S
T
N
A
L
K
D
L
Site 38
T401
L
K
D
L
L
C
H
T
G
G
L
S
K
L
G
Site 39
T440
I
R
A
E
L
M
C
T
L
R
E
V
R
Q
P
Site 40
S459
F
G
P
I
P
C
P
S
C
G
S
W
P
S
E
Site 41
S462
I
P
C
P
S
C
G
S
W
P
S
E
K
V
D
Site 42
S465
P
S
C
G
S
W
P
S
E
K
V
D
F
H
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation