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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GFI1B
Full Name:
Zinc finger protein Gfi-1b
Alias:
Growth factor independent protein 1B;Potential regulator of CDKN1A translocated in CML
Type:
Mass (Da):
37492
Number AA:
330
UniProt ID:
Q5VTD9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
P
R
S
F
L
V
K
S
K
K
A
H
T
Y
H
Site 2
Y15
K
S
K
K
A
H
T
Y
H
Q
P
R
V
Q
E
Site 3
T32
P
L
W
P
P
A
L
T
P
V
P
R
D
Q
A
Site 4
S41
V
P
R
D
Q
A
P
S
N
S
P
V
L
S
T
Site 5
S43
R
D
Q
A
P
S
N
S
P
V
L
S
T
L
F
Site 6
S47
P
S
N
S
P
V
L
S
T
L
F
P
N
Q
C
Site 7
T58
P
N
Q
C
L
D
W
T
N
L
K
R
E
P
E
Site 8
S86
P
E
G
P
I
V
L
S
R
P
Q
D
G
D
S
Site 9
S93
S
R
P
Q
D
G
D
S
P
L
S
D
S
P
P
Site 10
S96
Q
D
G
D
S
P
L
S
D
S
P
P
F
Y
K
Site 11
S98
G
D
S
P
L
S
D
S
P
P
F
Y
K
P
S
Site 12
Y102
L
S
D
S
P
P
F
Y
K
P
S
F
S
W
D
Site 13
S105
S
P
P
F
Y
K
P
S
F
S
W
D
T
L
A
Site 14
S107
P
F
Y
K
P
S
F
S
W
D
T
L
A
T
T
Site 15
T110
K
P
S
F
S
W
D
T
L
A
T
T
Y
G
H
Site 16
T114
S
W
D
T
L
A
T
T
Y
G
H
S
Y
R
Q
Site 17
S118
L
A
T
T
Y
G
H
S
Y
R
Q
A
P
S
T
Site 18
S124
H
S
Y
R
Q
A
P
S
T
M
Q
S
A
F
L
Site 19
T125
S
Y
R
Q
A
P
S
T
M
Q
S
A
F
L
E
Site 20
S128
Q
A
P
S
T
M
Q
S
A
F
L
E
H
S
V
Site 21
S134
Q
S
A
F
L
E
H
S
V
S
L
Y
G
S
P
Site 22
S140
H
S
V
S
L
Y
G
S
P
L
V
P
S
T
E
Site 23
S145
Y
G
S
P
L
V
P
S
T
E
P
A
L
D
F
Site 24
T146
G
S
P
L
V
P
S
T
E
P
A
L
D
F
S
Site 25
S153
T
E
P
A
L
D
F
S
L
R
Y
S
P
G
M
Site 26
Y156
A
L
D
F
S
L
R
Y
S
P
G
M
D
A
Y
Site 27
S157
L
D
F
S
L
R
Y
S
P
G
M
D
A
Y
H
Site 28
Y163
Y
S
P
G
M
D
A
Y
H
C
V
K
C
N
K
Site 29
S173
V
K
C
N
K
V
F
S
T
P
H
G
L
E
V
Site 30
T174
K
C
N
K
V
F
S
T
P
H
G
L
E
V
H
Site 31
S185
L
E
V
H
V
R
R
S
H
S
G
T
R
P
F
Site 32
S187
V
H
V
R
R
S
H
S
G
T
R
P
F
A
C
Site 33
T189
V
R
R
S
H
S
G
T
R
P
F
A
C
D
I
Site 34
S206
K
T
F
G
H
A
V
S
L
E
Q
H
T
H
V
Site 35
S215
E
Q
H
T
H
V
H
S
Q
E
R
S
F
E
C
Site 36
S232
C
G
K
A
F
K
R
S
S
T
L
S
T
H
L
Site 37
S233
G
K
A
F
K
R
S
S
T
L
S
T
H
L
L
Site 38
T234
K
A
F
K
R
S
S
T
L
S
T
H
L
L
I
Site 39
S236
F
K
R
S
S
T
L
S
T
H
L
L
I
H
S
Site 40
T237
K
R
S
S
T
L
S
T
H
L
L
I
H
S
D
Site 41
S243
S
T
H
L
L
I
H
S
D
T
R
P
Y
P
C
Site 42
T245
H
L
L
I
H
S
D
T
R
P
Y
P
C
Q
F
Site 43
Y248
I
H
S
D
T
R
P
Y
P
C
Q
F
C
G
K
Site 44
Y268
S
D
M
K
K
H
T
Y
I
H
T
G
E
K
P
Site 45
S286
Q
V
C
G
K
A
F
S
Q
S
S
N
L
I
T
Site 46
S288
C
G
K
A
F
S
Q
S
S
N
L
I
T
H
S
Site 47
S289
G
K
A
F
S
Q
S
S
N
L
I
T
H
S
R
Site 48
T293
S
Q
S
S
N
L
I
T
H
S
R
K
H
T
G
Site 49
S295
S
S
N
L
I
T
H
S
R
K
H
T
G
F
K
Site 50
T299
I
T
H
S
R
K
H
T
G
F
K
P
F
S
C
Site 51
S325
D
L
R
R
H
R
E
S
Q
H
N
L
K
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation