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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRPF38B
Full Name:
Pre-mRNA-splicing factor 38B
Alias:
FLJ10330; NET1; PR38B; PRP38 pre-mRNA processing factor 38 domain containing B; Sarcoma antigen NY-SAR-27
Type:
RNA processing
Mass (Da):
64468
Number AA:
546
UniProt ID:
Q5VTL8
International Prot ID:
IPI00018098
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005681
GO:0030529
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006139
GO:0006396
GO:0006397
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
A
N
N
S
P
A
L
T
G
N
S
Site 2
T9
A
N
N
S
P
A
L
T
G
N
S
Q
P
Q
H
Site 3
S12
S
P
A
L
T
G
N
S
Q
P
Q
H
Q
A
A
Site 4
S40
G
A
T
K
P
A
V
S
G
K
Q
G
N
V
L
Site 5
Y71
T
N
I
L
S
S
P
Y
F
K
V
Q
L
Y
E
Site 6
Y77
P
Y
F
K
V
Q
L
Y
E
L
K
T
Y
H
E
Site 7
Y82
Q
L
Y
E
L
K
T
Y
H
E
V
V
D
E
I
Site 8
Y90
H
E
V
V
D
E
I
Y
F
K
V
T
H
V
E
Site 9
T106
W
E
K
G
S
R
K
T
A
G
Q
T
G
M
C
Site 10
T150
K
Q
V
M
G
L
I
T
H
T
D
S
P
Y
I
Site 11
T152
V
M
G
L
I
T
H
T
D
S
P
Y
I
R
A
Site 12
S154
G
L
I
T
H
T
D
S
P
Y
I
R
A
L
G
Site 13
Y156
I
T
H
T
D
S
P
Y
I
R
A
L
G
F
M
Site 14
Y164
I
R
A
L
G
F
M
Y
I
R
Y
T
Q
P
P
Site 15
Y167
L
G
F
M
Y
I
R
Y
T
Q
P
P
T
D
L
Site 16
T235
N
I
D
Q
Q
I
K
T
R
P
R
K
I
K
K
Site 17
S260
R
H
V
E
R
R
R
S
R
S
P
R
R
S
L
Site 18
S262
V
E
R
R
R
S
R
S
P
R
R
S
L
S
P
Site 19
S266
R
S
R
S
P
R
R
S
L
S
P
R
R
S
P
Site 20
S268
R
S
P
R
R
S
L
S
P
R
R
S
P
R
R
Site 21
S272
R
S
L
S
P
R
R
S
P
R
R
S
R
S
R
Site 22
S276
P
R
R
S
P
R
R
S
R
S
R
S
H
H
R
Site 23
S278
R
S
P
R
R
S
R
S
R
S
H
H
R
E
G
Site 24
S280
P
R
R
S
R
S
R
S
H
H
R
E
G
H
G
Site 25
S288
H
H
R
E
G
H
G
S
S
S
F
D
R
E
L
Site 26
S289
H
R
E
G
H
G
S
S
S
F
D
R
E
L
E
Site 27
S290
R
E
G
H
G
S
S
S
F
D
R
E
L
E
R
Site 28
S318
R
E
K
E
R
R
R
S
R
S
I
D
R
G
L
Site 29
S320
K
E
R
R
R
S
R
S
I
D
R
G
L
E
R
Site 30
S330
R
G
L
E
R
R
R
S
R
S
R
E
R
H
R
Site 31
S332
L
E
R
R
R
S
R
S
R
E
R
H
R
S
R
Site 32
S338
R
S
R
E
R
H
R
S
R
S
R
S
R
D
R
Site 33
S340
R
E
R
H
R
S
R
S
R
S
R
D
R
K
G
Site 34
S342
R
H
R
S
R
S
R
S
R
D
R
K
G
D
R
Site 35
Y370
G
R
R
R
D
R
D
Y
D
K
E
R
G
N
E
Site 36
S385
R
E
K
E
R
E
R
S
R
E
R
S
K
E
Q
Site 37
S389
R
E
R
S
R
E
R
S
K
E
Q
R
S
R
G
Site 38
S419
H
R
D
D
K
R
D
S
K
K
E
K
K
H
S
Site 39
S426
S
K
K
E
K
K
H
S
R
S
R
S
R
E
R
Site 40
S428
K
E
K
K
H
S
R
S
R
S
R
E
R
K
H
Site 41
S430
K
K
H
S
R
S
R
S
R
E
R
K
H
R
S
Site 42
S437
S
R
E
R
K
H
R
S
R
S
R
S
R
N
A
Site 43
S439
E
R
K
H
R
S
R
S
R
S
R
N
A
G
K
Site 44
S441
K
H
R
S
R
S
R
S
R
N
A
G
K
R
S
Site 45
S448
S
R
N
A
G
K
R
S
R
S
R
S
K
E
K
Site 46
S450
N
A
G
K
R
S
R
S
R
S
K
E
K
S
S
Site 47
S452
G
K
R
S
R
S
R
S
K
E
K
S
S
K
H
Site 48
S456
R
S
R
S
K
E
K
S
S
K
H
K
N
E
S
Site 49
S457
S
R
S
K
E
K
S
S
K
H
K
N
E
S
K
Site 50
S463
S
S
K
H
K
N
E
S
K
E
K
S
N
K
R
Site 51
S467
K
N
E
S
K
E
K
S
N
K
R
S
R
S
G
Site 52
S471
K
E
K
S
N
K
R
S
R
S
G
S
Q
G
R
Site 53
S473
K
S
N
K
R
S
R
S
G
S
Q
G
R
T
D
Site 54
S475
N
K
R
S
R
S
G
S
Q
G
R
T
D
S
V
Site 55
T479
R
S
G
S
Q
G
R
T
D
S
V
E
K
S
K
Site 56
S481
G
S
Q
G
R
T
D
S
V
E
K
S
K
K
R
Site 57
S485
R
T
D
S
V
E
K
S
K
K
R
E
H
S
P
Site 58
S491
K
S
K
K
R
E
H
S
P
S
K
E
K
S
R
Site 59
S493
K
K
R
E
H
S
P
S
K
E
K
S
R
K
R
Site 60
S497
H
S
P
S
K
E
K
S
R
K
R
S
R
S
K
Site 61
S501
K
E
K
S
R
K
R
S
R
S
K
E
R
S
H
Site 62
S503
K
S
R
K
R
S
R
S
K
E
R
S
H
K
R
Site 63
S507
R
S
R
S
K
E
R
S
H
K
R
D
H
S
D
Site 64
S513
R
S
H
K
R
D
H
S
D
S
K
D
Q
S
D
Site 65
S515
H
K
R
D
H
S
D
S
K
D
Q
S
D
K
H
Site 66
S519
H
S
D
S
K
D
Q
S
D
K
H
D
R
R
R
Site 67
S527
D
K
H
D
R
R
R
S
Q
S
I
E
Q
E
S
Site 68
S529
H
D
R
R
R
S
Q
S
I
E
Q
E
S
Q
E
Site 69
S534
S
Q
S
I
E
Q
E
S
Q
E
K
Q
H
K
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation