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Updated November 2019
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Protein Info
Short Name:
MYOM3
Full Name:
Myomesin-3
Alias:
FLJ35961; Myom3; Myomesin family member 3; Myomesin family, member 3
Type:
Unknown function
Mass (Da):
162171
Number AA:
1437
UniProt ID:
Q5VTT5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
T
L
P
H
S
L
G
G
A
G
D
P
Site 2
S39
Q
K
E
E
R
Q
H
S
L
R
M
G
S
S
V
Site 3
S44
Q
H
S
L
R
M
G
S
S
V
R
R
R
T
F
Site 4
S45
H
S
L
R
M
G
S
S
V
R
R
R
T
F
R
Site 5
T50
G
S
S
V
R
R
R
T
F
R
S
S
E
E
E
Site 6
S53
V
R
R
R
T
F
R
S
S
E
E
E
H
E
F
Site 7
S54
R
R
R
T
F
R
S
S
E
E
E
H
E
F
S
Site 8
S61
S
E
E
E
H
E
F
S
A
A
D
Y
A
L
A
Site 9
S80
L
T
A
S
S
E
L
S
W
E
A
Q
L
R
R
Site 10
T89
E
A
Q
L
R
R
Q
T
S
A
V
E
L
E
E
Site 11
S90
A
Q
L
R
R
Q
T
S
A
V
E
L
E
E
R
Site 12
T130
R
Q
R
R
D
W
K
T
L
R
R
R
T
E
E
Site 13
T135
W
K
T
L
R
R
R
T
E
E
K
V
Q
E
A
Site 14
Y150
K
E
L
R
E
L
C
Y
G
R
G
P
W
F
W
Site 15
S180
L
T
C
T
V
Q
A
S
P
P
P
Q
V
T
W
Site 16
Y188
P
P
P
Q
V
T
W
Y
K
N
D
T
R
I
D
Site 17
T207
R
A
G
K
Y
R
I
T
N
N
Y
G
L
L
S
Site 18
Y210
K
Y
R
I
T
N
N
Y
G
L
L
S
L
E
I
Site 19
S214
T
N
N
Y
G
L
L
S
L
E
I
R
R
C
A
Site 20
S225
R
R
C
A
I
E
D
S
A
T
Y
T
V
R
V
Site 21
T227
C
A
I
E
D
S
A
T
Y
T
V
R
V
K
N
Site 22
T229
I
E
D
S
A
T
Y
T
V
R
V
K
N
A
H
Site 23
S241
N
A
H
G
Q
A
S
S
F
A
K
V
L
V
R
Site 24
S259
G
K
D
A
G
F
D
S
E
I
F
K
R
S
T
Site 25
T266
S
E
I
F
K
R
S
T
F
G
P
S
V
E
F
Site 26
S270
K
R
S
T
F
G
P
S
V
E
F
T
S
V
L
Site 27
S289
A
R
E
K
E
P
F
S
L
S
C
L
F
S
E
Site 28
S291
E
K
E
P
F
S
L
S
C
L
F
S
E
D
V
Site 29
S303
E
D
V
L
D
A
E
S
I
Q
W
F
R
D
G
Site 30
S311
I
Q
W
F
R
D
G
S
L
L
R
S
S
R
R
Site 31
S315
R
D
G
S
L
L
R
S
S
R
R
R
K
I
L
Site 32
S316
D
G
S
L
L
R
S
S
R
R
R
K
I
L
Y
Site 33
Y323
S
R
R
R
K
I
L
Y
T
D
R
Q
A
S
L
Site 34
T324
R
R
R
K
I
L
Y
T
D
R
Q
A
S
L
K
Site 35
S329
L
Y
T
D
R
Q
A
S
L
K
V
S
C
T
Y
Site 36
S333
R
Q
A
S
L
K
V
S
C
T
Y
K
E
D
E
Site 37
T335
A
S
L
K
V
S
C
T
Y
K
E
D
E
G
L
Site 38
Y336
S
L
K
V
S
C
T
Y
K
E
D
E
G
L
Y
Site 39
Y343
Y
K
E
D
E
G
L
Y
M
V
R
V
P
S
P
Site 40
S349
L
Y
M
V
R
V
P
S
P
F
G
P
R
E
Q
Site 41
S357
P
F
G
P
R
E
Q
S
T
Y
V
L
V
R
D
Site 42
Y359
G
P
R
E
Q
S
T
Y
V
L
V
R
D
A
E
Site 43
S375
E
N
P
G
A
P
G
S
P
L
N
V
R
C
L
Site 44
T392
N
R
D
C
L
I
L
T
W
A
P
P
S
D
T
Site 45
S397
I
L
T
W
A
P
P
S
D
T
R
G
N
P
I
Site 46
T405
D
T
R
G
N
P
I
T
A
Y
T
I
E
R
C
Site 47
Y407
R
G
N
P
I
T
A
Y
T
I
E
R
C
Q
G
Site 48
S442
Q
G
L
V
E
G
Q
S
Y
R
F
R
V
R
A
Site 49
Y443
G
L
V
E
G
Q
S
Y
R
F
R
V
R
A
I
Site 50
S451
R
F
R
V
R
A
I
S
R
V
G
S
S
V
P
Site 51
S455
R
A
I
S
R
V
G
S
S
V
P
S
K
A
S
Site 52
S456
A
I
S
R
V
G
S
S
V
P
S
K
A
S
E
Site 53
T477
H
D
A
A
R
R
K
T
E
I
P
F
D
L
G
Site 54
S490
L
G
N
K
I
T
I
S
T
D
A
F
E
D
T
Site 55
T497
S
T
D
A
F
E
D
T
V
T
I
P
S
P
P
Site 56
T499
D
A
F
E
D
T
V
T
I
P
S
P
P
T
N
Site 57
S502
E
D
T
V
T
I
P
S
P
P
T
N
V
H
A
Site 58
T505
V
T
I
P
S
P
P
T
N
V
H
A
S
E
I
Site 59
S510
P
P
T
N
V
H
A
S
E
I
R
E
A
Y
V
Site 60
Y516
A
S
E
I
R
E
A
Y
V
V
L
A
W
E
E
Site 61
S525
V
L
A
W
E
E
P
S
P
R
D
R
A
P
L
Site 62
T533
P
R
D
R
A
P
L
T
Y
S
L
E
K
S
V
Site 63
S535
D
R
A
P
L
T
Y
S
L
E
K
S
V
I
G
Site 64
S539
L
T
Y
S
L
E
K
S
V
I
G
S
G
T
W
Site 65
S543
L
E
K
S
V
I
G
S
G
T
W
E
A
I
S
Site 66
S550
S
G
T
W
E
A
I
S
S
E
S
P
V
R
S
Site 67
S551
G
T
W
E
A
I
S
S
E
S
P
V
R
S
P
Site 68
S553
W
E
A
I
S
S
E
S
P
V
R
S
P
R
F
Site 69
S557
S
S
E
S
P
V
R
S
P
R
F
A
V
L
D
Site 70
S570
L
D
L
E
K
K
K
S
Y
V
F
R
V
R
A
Site 71
Y571
D
L
E
K
K
K
S
Y
V
F
R
V
R
A
M
Site 72
Y581
R
V
R
A
M
N
Q
Y
G
L
S
D
P
S
E
Site 73
S584
A
M
N
Q
Y
G
L
S
D
P
S
E
P
S
E
Site 74
S587
Q
Y
G
L
S
D
P
S
E
P
S
E
P
I
A
Site 75
S590
L
S
D
P
S
E
P
S
E
P
I
A
L
R
G
Site 76
T601
A
L
R
G
P
P
A
T
L
P
P
P
A
Q
V
Site 77
T614
Q
V
Q
A
F
R
D
T
Q
T
S
V
S
L
T
Site 78
T616
Q
A
F
R
D
T
Q
T
S
V
S
L
T
W
D
Site 79
S617
A
F
R
D
T
Q
T
S
V
S
L
T
W
D
P
Site 80
S619
R
D
T
Q
T
S
V
S
L
T
W
D
P
V
K
Site 81
T621
T
Q
T
S
V
S
L
T
W
D
P
V
K
D
P
Site 82
Y633
K
D
P
E
L
L
G
Y
Y
I
Y
S
R
K
V
Site 83
Y634
D
P
E
L
L
G
Y
Y
I
Y
S
R
K
V
G
Site 84
Y636
E
L
L
G
Y
Y
I
Y
S
R
K
V
G
T
S
Site 85
T647
V
G
T
S
E
W
Q
T
V
N
N
K
P
I
Q
Site 86
T659
P
I
Q
G
T
R
F
T
V
P
G
L
R
T
G
Site 87
Y669
G
L
R
T
G
K
E
Y
E
F
C
V
R
S
V
Site 88
S675
E
Y
E
F
C
V
R
S
V
S
E
A
G
V
G
Site 89
S677
E
F
C
V
R
S
V
S
E
A
G
V
G
E
S
Site 90
S685
E
A
G
V
G
E
S
S
A
A
T
E
P
I
R
Site 91
T688
V
G
E
S
S
A
A
T
E
P
I
R
V
K
Q
Site 92
T699
R
V
K
Q
A
L
A
T
P
S
A
P
Y
G
F
Site 93
Y734
G
G
G
K
I
L
G
Y
F
L
D
Q
H
D
S
Site 94
S762
P
T
R
V
C
K
V
S
D
L
H
E
G
H
F
Site 95
Y770
D
L
H
E
G
H
F
Y
E
F
R
A
R
A
A
Site 96
S790
G
E
L
S
A
P
S
S
L
F
E
C
K
E
W
Site 97
Y806
M
P
Q
P
G
P
P
Y
D
V
R
A
S
E
V
Site 98
S811
P
P
Y
D
V
R
A
S
E
V
R
A
T
S
L
Site 99
T816
R
A
S
E
V
R
A
T
S
L
V
L
Q
W
E
Site 100
S817
A
S
E
V
R
A
T
S
L
V
L
Q
W
E
P
Site 101
Y827
L
Q
W
E
P
P
L
Y
M
G
A
G
P
V
T
Site 102
T834
Y
M
G
A
G
P
V
T
G
Y
H
V
S
F
Q
Site 103
Y836
G
A
G
P
V
T
G
Y
H
V
S
F
Q
E
E
Site 104
S839
P
V
T
G
Y
H
V
S
F
Q
E
E
G
S
E
Site 105
T852
S
E
Q
W
K
P
V
T
P
G
P
I
S
G
T
Site 106
S857
P
V
T
P
G
P
I
S
G
T
H
L
R
V
S
Site 107
S864
S
G
T
H
L
R
V
S
D
L
Q
P
G
K
S
Site 108
S871
S
D
L
Q
P
G
K
S
Y
V
F
Q
V
Q
A
Site 109
Y872
D
L
Q
P
G
K
S
Y
V
F
Q
V
Q
A
M
Site 110
S888
S
A
G
L
G
Q
P
S
M
P
T
D
P
V
L
Site 111
T891
L
G
Q
P
S
M
P
T
D
P
V
L
L
E
D
Site 112
S927
E
A
P
E
A
P
D
S
S
E
F
Q
W
S
K
Site 113
S928
A
P
E
A
P
D
S
S
E
F
Q
W
S
K
D
Site 114
S933
D
S
S
E
F
Q
W
S
K
D
Y
K
G
P
L
Site 115
Y936
E
F
Q
W
S
K
D
Y
K
G
P
L
D
P
Q
Site 116
S954
I
E
D
K
V
N
K
S
K
V
I
L
K
E
P
Site 117
T974
G
T
Y
S
V
I
V
T
D
A
D
E
D
I
S
Site 118
S981
T
D
A
D
E
D
I
S
A
S
H
T
L
T
E
Site 119
T985
E
D
I
S
A
S
H
T
L
T
E
E
E
L
E
Site 120
T987
I
S
A
S
H
T
L
T
E
E
E
L
E
K
L
Site 121
S1049
N
N
K
E
I
F
S
S
P
N
R
K
I
N
F
Site 122
S1071
E
V
I
I
Q
N
L
S
E
E
D
K
G
S
Y
Site 123
S1077
L
S
E
E
D
K
G
S
Y
T
A
Q
L
Q
D
Site 124
T1094
A
K
N
Q
I
T
L
T
L
V
D
D
D
F
D
Site 125
Y1121
W
K
R
K
Q
G
P
Y
F
E
R
P
L
Q
W
Site 126
Y1165
A
E
M
P
D
G
Q
Y
D
P
E
T
G
T
G
Site 127
T1169
D
G
Q
Y
D
P
E
T
G
T
G
L
L
C
I
Site 128
Y1187
S
K
K
D
K
G
I
Y
R
A
M
V
S
D
D
Site 129
S1192
G
I
Y
R
A
M
V
S
D
D
R
G
E
D
D
Site 130
T1200
D
D
R
G
E
D
D
T
I
L
D
L
T
G
D
Site 131
S1240
E
E
G
I
R
I
F
S
K
V
K
Y
Y
N
V
Site 132
Y1244
R
I
F
S
K
V
K
Y
Y
N
V
E
Y
M
K
Site 133
Y1245
I
F
S
K
V
K
Y
Y
N
V
E
Y
M
K
T
Site 134
S1263
H
K
D
K
R
L
E
S
G
D
R
I
R
T
G
Site 135
T1269
E
S
G
D
R
I
R
T
G
T
T
L
D
E
I
Site 136
T1271
G
D
R
I
R
T
G
T
T
L
D
E
I
W
L
Site 137
S1286
H
I
L
D
P
K
D
S
D
K
G
K
Y
T
L
Site 138
Y1291
K
D
S
D
K
G
K
Y
T
L
E
I
A
A
G
Site 139
S1305
G
K
E
V
R
Q
L
S
T
D
L
S
G
Q
A
Site 140
S1309
R
Q
L
S
T
D
L
S
G
Q
A
F
E
D
A
Site 141
T1325
A
E
H
Q
R
L
K
T
L
A
I
I
E
K
N
Site 142
T1345
R
G
L
P
D
V
A
T
I
M
E
D
K
T
L
Site 143
T1363
C
I
V
S
G
D
P
T
P
E
I
S
W
L
K
Site 144
T1376
L
K
N
D
Q
P
V
T
F
L
D
R
Y
R
M
Site 145
Y1381
P
V
T
F
L
D
R
Y
R
M
E
V
R
G
T
Site 146
T1388
Y
R
M
E
V
R
G
T
E
V
T
I
T
I
E
Site 147
T1391
E
V
R
G
T
E
V
T
I
T
I
E
K
V
N
Site 148
T1393
R
G
T
E
V
T
I
T
I
E
K
V
N
S
E
Site 149
S1399
I
T
I
E
K
V
N
S
E
D
S
G
R
Y
G
Site 150
S1402
E
K
V
N
S
E
D
S
G
R
Y
G
V
F
V
Site 151
Y1413
G
V
F
V
K
N
K
Y
G
S
E
T
G
Q
V
Site 152
T1421
G
S
E
T
G
Q
V
T
I
S
V
F
K
H
G
Site 153
S1423
E
T
G
Q
V
T
I
S
V
F
K
H
G
D
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation