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Updated November 2019
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Protein Info
Short Name:
PDE4DIP
Full Name:
Myomegalin
Alias:
Cardiomyopathy associated 2; CMYA2; KIAA0454; KIAA0477; MMGL; MYOME; Phosphodiesterase 4D interacting; Phosphodiesterase 4D interacting protein; Phosphodiesterase 4D interacting protein (myomegalin)
Type:
Adaptor/scaffold
Mass (Da):
91115
Number AA:
1148
UniProt ID:
Q5VU43
International Prot ID:
IPI00002449
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005813
GO:0005737
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
S
N
G
Y
R
T
L
S
Q
H
L
N
D
Site 2
S9
S
N
G
Y
R
T
L
S
Q
H
L
N
D
L
K
Site 3
Y27
F
S
L
K
L
R
I
Y
F
L
E
E
R
M
Q
Site 4
Y37
E
E
R
M
Q
Q
K
Y
E
A
S
R
E
D
I
Site 5
Y45
E
A
S
R
E
D
I
Y
K
R
N
I
E
L
K
Site 6
S57
E
L
K
V
E
V
E
S
L
K
R
E
L
Q
D
Site 7
T72
K
K
Q
H
L
D
K
T
W
A
D
V
E
N
L
Site 8
S81
A
D
V
E
N
L
N
S
Q
N
E
A
E
L
R
Site 9
Y164
D
Q
V
K
P
D
Q
Y
T
E
A
L
A
Q
R
Site 10
S181
R
I
E
E
L
N
Q
S
L
A
A
Q
E
R
L
Site 11
S193
E
R
L
V
E
Q
L
S
R
E
K
Q
Q
L
L
Site 12
S208
H
L
L
E
E
P
T
S
M
E
V
Q
P
M
T
Site 13
S226
L
K
Q
Q
K
L
N
S
H
E
T
T
I
T
Q
Site 14
T230
K
L
N
S
H
E
T
T
I
T
Q
Q
S
V
S
Site 15
T232
N
S
H
E
T
T
I
T
Q
Q
S
V
S
D
S
Site 16
S235
E
T
T
I
T
Q
Q
S
V
S
D
S
H
L
A
Site 17
S237
T
I
T
Q
Q
S
V
S
D
S
H
L
A
E
L
Site 18
S239
T
Q
Q
S
V
S
D
S
H
L
A
E
L
Q
E
Site 19
S276
L
K
C
A
Q
E
S
S
Q
K
Q
D
G
T
I
Site 20
S292
N
L
K
E
T
L
K
S
R
E
R
E
T
E
E
Site 21
T297
L
K
S
R
E
R
E
T
E
E
L
Y
Q
V
I
Site 22
Y301
E
R
E
T
E
E
L
Y
Q
V
I
E
G
Q
N
Site 23
S321
L
R
E
M
L
H
Q
S
Q
L
G
Q
L
H
S
Site 24
S328
S
Q
L
G
Q
L
H
S
S
E
G
T
S
P
A
Site 25
S329
Q
L
G
Q
L
H
S
S
E
G
T
S
P
A
Q
Site 26
S333
L
H
S
S
E
G
T
S
P
A
Q
Q
Q
V
A
Site 27
S415
Q
E
E
L
Q
N
K
S
Q
Q
L
R
A
W
E
Site 28
Y426
R
A
W
E
A
E
K
Y
N
E
I
R
T
Q
E
Site 29
S442
N
I
Q
H
L
N
H
S
L
S
H
K
E
Q
L
Site 30
S444
Q
H
L
N
H
S
L
S
H
K
E
Q
L
L
Q
Site 31
Y459
E
F
R
E
L
L
Q
Y
R
D
N
S
D
K
T
Site 32
S463
L
L
Q
Y
R
D
N
S
D
K
T
L
E
A
N
Site 33
T466
Y
R
D
N
S
D
K
T
L
E
A
N
E
M
L
Site 34
S528
E
R
L
R
D
V
L
S
S
N
E
A
T
M
Q
Site 35
S529
R
L
R
D
V
L
S
S
N
E
A
T
M
Q
S
Site 36
T533
V
L
S
S
N
E
A
T
M
Q
S
M
E
S
L
Site 37
S536
S
N
E
A
T
M
Q
S
M
E
S
L
L
R
A
Site 38
S539
A
T
M
Q
S
M
E
S
L
L
R
A
K
G
L
Site 39
S552
G
L
E
V
E
Q
L
S
T
T
C
Q
N
L
Q
Site 40
T553
L
E
V
E
Q
L
S
T
T
C
Q
N
L
Q
W
Site 41
S570
E
E
M
E
T
K
F
S
R
W
Q
K
E
Q
E
Site 42
S586
I
I
Q
Q
L
Q
T
S
L
H
D
R
N
K
E
Site 43
S598
N
K
E
V
E
D
L
S
A
T
L
L
C
K
L
Site 44
S610
C
K
L
G
P
G
Q
S
E
I
A
E
E
L
C
Site 45
S632
R
M
L
Q
D
L
L
S
D
R
N
K
Q
V
L
Site 46
S651
E
I
Q
G
L
L
Q
S
V
S
T
R
E
Q
E
Site 47
S653
Q
G
L
L
Q
S
V
S
T
R
E
Q
E
S
Q
Site 48
S675
Q
A
L
M
E
R
N
S
E
L
Q
A
L
R
Q
Site 49
Y683
E
L
Q
A
L
R
Q
Y
L
G
G
R
D
S
L
Site 50
S689
Q
Y
L
G
G
R
D
S
L
M
S
Q
A
P
I
Site 51
S692
G
G
R
D
S
L
M
S
Q
A
P
I
S
N
Q
Site 52
S697
L
M
S
Q
A
P
I
S
N
Q
Q
A
E
V
T
Site 53
T704
S
N
Q
Q
A
E
V
T
P
T
G
C
L
G
K
Site 54
T706
Q
Q
A
E
V
T
P
T
G
C
L
G
K
Q
T
Site 55
T713
T
G
C
L
G
K
Q
T
D
Q
G
S
M
Q
I
Site 56
S717
G
K
Q
T
D
Q
G
S
M
Q
I
P
S
R
D
Site 57
S722
Q
G
S
M
Q
I
P
S
R
D
D
S
T
S
L
Site 58
S726
Q
I
P
S
R
D
D
S
T
S
L
T
A
K
E
Site 59
T727
I
P
S
R
D
D
S
T
S
L
T
A
K
E
D
Site 60
S728
P
S
R
D
D
S
T
S
L
T
A
K
E
D
V
Site 61
T730
R
D
D
S
T
S
L
T
A
K
E
D
V
S
I
Site 62
S736
L
T
A
K
E
D
V
S
I
P
R
S
T
L
G
Site 63
S740
E
D
V
S
I
P
R
S
T
L
G
D
L
D
T
Site 64
T741
D
V
S
I
P
R
S
T
L
G
D
L
D
T
V
Site 65
T747
S
T
L
G
D
L
D
T
V
A
G
L
E
K
E
Site 66
S756
A
G
L
E
K
E
L
S
N
A
K
E
E
L
E
Site 67
S772
M
A
K
K
E
R
E
S
Q
M
E
L
S
A
L
Site 68
S777
R
E
S
Q
M
E
L
S
A
L
Q
S
M
M
A
Site 69
S781
M
E
L
S
A
L
Q
S
M
M
A
V
Q
E
E
Site 70
S799
V
Q
A
A
D
M
E
S
L
T
R
N
I
Q
I
Site 71
S843
L
L
R
E
K
V
A
S
V
E
S
Q
G
Q
E
Site 72
S852
E
S
Q
G
Q
E
I
S
G
N
R
R
Q
Q
L
Site 73
S871
E
G
L
V
D
E
R
S
R
L
N
E
A
L
Q
Site 74
Y884
L
Q
A
E
R
Q
L
Y
S
S
L
V
K
F
H
Site 75
S885
Q
A
E
R
Q
L
Y
S
S
L
V
K
F
H
A
Site 76
S886
A
E
R
Q
L
Y
S
S
L
V
K
F
H
A
H
Site 77
S896
K
F
H
A
H
P
E
S
S
E
R
D
R
T
L
Site 78
S897
F
H
A
H
P
E
S
S
E
R
D
R
T
L
Q
Site 79
T902
E
S
S
E
R
D
R
T
L
Q
V
E
L
E
G
Site 80
T933
E
R
L
N
R
L
E
T
L
A
A
I
G
G
A
Site 81
T946
G
A
A
A
G
D
D
T
E
D
T
S
T
E
F
Site 82
T949
A
G
D
D
T
E
D
T
S
T
E
F
T
D
S
Site 83
S950
G
D
D
T
E
D
T
S
T
E
F
T
D
S
I
Site 84
T951
D
D
T
E
D
T
S
T
E
F
T
D
S
I
E
Site 85
T954
E
D
T
S
T
E
F
T
D
S
I
E
E
E
A
Site 86
S956
T
S
T
E
F
T
D
S
I
E
E
E
A
A
H
Site 87
T983
K
S
L
A
T
V
E
T
Q
N
P
S
F
S
P
Site 88
S987
T
V
E
T
Q
N
P
S
F
S
P
P
S
P
M
Site 89
S989
E
T
Q
N
P
S
F
S
P
P
S
P
M
G
G
Site 90
S992
N
P
S
F
S
P
P
S
P
M
G
G
D
S
N
Site 91
S998
P
S
P
M
G
G
D
S
N
R
C
L
Q
E
E
Site 92
S1040
Q
I
E
E
A
G
F
S
S
V
S
H
I
R
N
Site 93
S1041
I
E
E
A
G
F
S
S
V
S
H
I
R
N
T
Site 94
S1051
H
I
R
N
T
M
L
S
L
C
L
E
N
A
E
Site 95
S1094
V
V
T
K
E
G
L
S
E
S
S
L
Q
A
E
Site 96
S1097
K
E
G
L
S
E
S
S
L
Q
A
E
F
R
K
Site 97
S1126
L
K
E
Q
L
V
L
S
S
K
E
G
N
S
K
Site 98
S1127
K
E
Q
L
V
L
S
S
K
E
G
N
S
K
L
Site 99
T1135
K
E
G
N
S
K
L
T
P
E
L
L
V
H
L
Site 100
T1151
S
T
I
E
R
I
N
T
E
L
V
G
S
P
G
Site 101
S1156
I
N
T
E
L
V
G
S
P
G
K
H
Q
H
Q
Site 102
T1169
H
Q
E
E
G
N
V
T
V
R
P
F
P
R
P
Site 103
S1178
R
P
F
P
R
P
Q
S
L
D
L
G
A
T
F
Site 104
T1184
Q
S
L
D
L
G
A
T
F
T
V
D
A
H
Q
Site 105
S1196
A
H
Q
L
D
N
Q
S
Q
P
R
D
P
G
P
Site 106
S1205
P
R
D
P
G
P
Q
S
A
F
S
L
P
G
S
Site 107
S1208
P
G
P
Q
S
A
F
S
L
P
G
S
T
Q
H
Site 108
S1212
S
A
F
S
L
P
G
S
T
Q
H
L
R
S
Q
Site 109
S1218
G
S
T
Q
H
L
R
S
Q
L
S
Q
C
K
Q
Site 110
S1221
Q
H
L
R
S
Q
L
S
Q
C
K
Q
R
Y
Q
Site 111
Y1251
Q
A
N
E
L
E
K
Y
R
V
M
L
T
G
E
Site 112
S1259
R
V
M
L
T
G
E
S
L
V
K
Q
D
S
K
Site 113
S1265
E
S
L
V
K
Q
D
S
K
Q
I
Q
V
D
L
Site 114
Y1277
V
D
L
Q
D
L
G
Y
E
T
C
G
R
S
E
Site 115
T1279
L
Q
D
L
G
Y
E
T
C
G
R
S
E
N
E
Site 116
T1292
N
E
A
E
R
E
E
T
T
S
P
E
C
E
E
Site 117
S1294
A
E
R
E
E
T
T
S
P
E
C
E
E
H
N
Site 118
S1302
P
E
C
E
E
H
N
S
L
K
E
M
V
L
M
Site 119
S1314
V
L
M
E
G
L
C
S
E
Q
G
R
R
G
S
Site 120
S1321
S
E
Q
G
R
R
G
S
T
L
A
S
S
S
E
Site 121
T1322
E
Q
G
R
R
G
S
T
L
A
S
S
S
E
R
Site 122
S1325
R
R
G
S
T
L
A
S
S
S
E
R
K
P
L
Site 123
S1326
R
G
S
T
L
A
S
S
S
E
R
K
P
L
E
Site 124
S1327
G
S
T
L
A
S
S
S
E
R
K
P
L
E
N
Site 125
Y1345
K
Q
E
E
F
R
V
Y
G
K
S
E
N
I
L
Site 126
S1348
E
F
R
V
Y
G
K
S
E
N
I
L
V
L
R
Site 127
S1377
K
V
I
Q
N
L
K
S
R
V
R
S
L
S
V
Site 128
S1381
N
L
K
S
R
V
R
S
L
S
V
T
S
D
Y
Site 129
S1383
K
S
R
V
R
S
L
S
V
T
S
D
Y
S
S
Site 130
T1385
R
V
R
S
L
S
V
T
S
D
Y
S
S
S
L
Site 131
S1386
V
R
S
L
S
V
T
S
D
Y
S
S
S
L
E
Site 132
Y1388
S
L
S
V
T
S
D
Y
S
S
S
L
E
R
P
Site 133
S1389
L
S
V
T
S
D
Y
S
S
S
L
E
R
P
W
Site 134
S1390
S
V
T
S
D
Y
S
S
S
L
E
R
P
W
K
Site 135
S1391
V
T
S
D
Y
S
S
S
L
E
R
P
W
K
L
Site 136
T1403
W
K
L
R
A
V
G
T
L
E
G
S
S
P
H
Site 137
S1407
A
V
G
T
L
E
G
S
S
P
H
S
V
P
D
Site 138
S1408
V
G
T
L
E
G
S
S
P
H
S
V
P
D
E
Site 139
S1411
L
E
G
S
S
P
H
S
V
P
D
E
D
E
G
Site 140
S1421
D
E
D
E
G
W
L
S
D
G
T
G
A
F
Y
Site 141
T1424
E
G
W
L
S
D
G
T
G
A
F
Y
S
P
G
Site 142
Y1428
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D
G
T
G
A
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Y
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L
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A
K
Site 143
S1429
D
G
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A
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K
K
Site 144
S1440
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A
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K
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Site 145
S1446
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A
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Site 146
S1467
K
L
A
E
E
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R
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A
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W
P
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K
Y
Site 147
S1469
A
E
E
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K
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D
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Site 148
Y1474
S
A
S
W
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K
Y
D
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I
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D
Q
Site 149
S1476
S
W
P
G
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Y
D
S
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I
Q
D
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A
R
Site 150
S1486
Q
D
Q
A
R
E
L
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Y
L
R
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I
R
Site 151
Y1487
D
Q
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Y
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K
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R
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Site 152
Y1500
R
E
G
R
G
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C
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R
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K
Site 153
T1509
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Site 154
S1512
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A
K
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E
D
L
L
R
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Site 155
S1519
S
F
E
D
L
L
R
S
N
D
I
D
Y
Y
L
Site 156
Y1524
L
R
S
N
D
I
D
Y
Y
L
G
Q
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F
R
Site 157
Y1525
R
S
N
D
I
D
Y
Y
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R
E
Site 158
S1529
I
D
Y
Y
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G
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R
E
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A
Q
Site 159
T1541
L
A
Q
G
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L
Site 160
T1545
S
Q
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Site 161
S1546
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Site 162
S1549
E
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Site 163
T1550
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K
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K
Site 164
S1555
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Site 165
S1570
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P
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A
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K
E
Site 166
S1591
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K
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A
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S
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Site 167
T1593
K
L
D
A
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S
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A
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Site 168
S1595
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A
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Site 169
S1596
A
R
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Site 170
S1597
R
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Site 171
S1601
P
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S
S
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R
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Site 172
S1603
S
S
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A
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Site 173
S1606
A
L
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Site 174
S1608
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D
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Site 175
S1609
D
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S
S
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L
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D
E
Site 176
T1610
S
H
R
S
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S
S
T
S
F
L
S
D
E
L
Site 177
S1611
H
R
S
P
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S
T
S
F
L
S
D
E
L
E
Site 178
S1614
P
S
S
T
S
F
L
S
D
E
L
E
A
C
S
Site 179
S1621
S
D
E
L
E
A
C
S
D
M
D
I
V
S
E
Site 180
Y1629
D
M
D
I
V
S
E
Y
T
H
Y
E
E
K
K
Site 181
Y1632
I
V
S
E
Y
T
H
Y
E
E
K
K
A
S
P
Site 182
S1638
H
Y
E
E
K
K
A
S
P
S
H
S
D
S
I
Site 183
S1640
E
E
K
K
A
S
P
S
H
S
D
S
I
H
H
Site 184
S1642
K
K
A
S
P
S
H
S
D
S
I
H
H
S
S
Site 185
S1644
A
S
P
S
H
S
D
S
I
H
H
S
S
H
S
Site 186
S1648
H
S
D
S
I
H
H
S
S
H
S
A
V
L
S
Site 187
S1649
S
D
S
I
H
H
S
S
H
S
A
V
L
S
S
Site 188
S1651
S
I
H
H
S
S
H
S
A
V
L
S
S
K
P
Site 189
S1655
S
S
H
S
A
V
L
S
S
K
P
S
S
T
S
Site 190
S1656
S
H
S
A
V
L
S
S
K
P
S
S
T
S
A
Site 191
S1659
A
V
L
S
S
K
P
S
S
T
S
A
S
Q
G
Site 192
S1660
V
L
S
S
K
P
S
S
T
S
A
S
Q
G
A
Site 193
S1662
S
S
K
P
S
S
T
S
A
S
Q
G
A
K
A
Site 194
S1664
K
P
S
S
T
S
A
S
Q
G
A
K
A
E
S
Site 195
S1671
S
Q
G
A
K
A
E
S
N
S
N
P
I
S
L
Site 196
S1673
G
A
K
A
E
S
N
S
N
P
I
S
L
P
T
Site 197
S1677
E
S
N
S
N
P
I
S
L
P
T
P
Q
N
T
Site 198
T1680
S
N
P
I
S
L
P
T
P
Q
N
T
P
K
E
Site 199
T1684
S
L
P
T
P
Q
N
T
P
K
E
A
N
Q
A
Site 200
S1699
H
S
G
F
H
F
H
S
I
P
K
L
A
S
L
Site 201
S1705
H
S
I
P
K
L
A
S
L
P
Q
A
P
L
P
Site 202
S1717
P
L
P
S
A
P
S
S
F
L
P
F
S
P
T
Site 203
S1756
L
Q
K
Q
L
G
E
S
A
S
T
V
P
P
A
Site 204
S1758
K
Q
L
G
E
S
A
S
T
V
P
P
A
S
T
Site 205
T1759
Q
L
G
E
S
A
S
T
V
P
P
A
S
T
A
Site 206
S1770
A
S
T
A
T
L
L
S
N
D
L
E
A
D
S
Site 207
S1777
S
N
D
L
E
A
D
S
S
Y
Y
L
N
S
A
Site 208
S1778
N
D
L
E
A
D
S
S
Y
Y
L
N
S
A
Q
Site 209
Y1779
D
L
E
A
D
S
S
Y
Y
L
N
S
A
Q
P
Site 210
Y1780
L
E
A
D
S
S
Y
Y
L
N
S
A
Q
P
H
Site 211
S1783
D
S
S
Y
Y
L
N
S
A
Q
P
H
S
P
P
Site 212
S1788
L
N
S
A
Q
P
H
S
P
P
R
G
T
I
E
Site 213
T1793
P
H
S
P
P
R
G
T
I
E
L
G
R
I
L
Site 214
Y1804
G
R
I
L
E
P
G
Y
L
G
S
S
G
K
W
Site 215
S1820
V
M
R
P
Q
K
G
S
V
S
G
D
L
S
S
Site 216
S1822
R
P
Q
K
G
S
V
S
G
D
L
S
S
G
S
Site 217
S1826
G
S
V
S
G
D
L
S
S
G
S
S
V
Y
Q
Site 218
S1827
S
V
S
G
D
L
S
S
G
S
S
V
Y
Q
L
Site 219
S1829
S
G
D
L
S
S
G
S
S
V
Y
Q
L
N
S
Site 220
S1830
G
D
L
S
S
G
S
S
V
Y
Q
L
N
S
K
Site 221
T1877
E
Q
L
E
H
R
L
T
S
T
A
R
G
R
G
Site 222
S1878
Q
L
E
H
R
L
T
S
T
A
R
G
R
G
S
Site 223
T1879
L
E
H
R
L
T
S
T
A
R
G
R
G
S
T
Site 224
S1885
S
T
A
R
G
R
G
S
T
S
N
F
Y
S
Q
Site 225
T1886
T
A
R
G
R
G
S
T
S
N
F
Y
S
Q
G
Site 226
S1887
A
R
G
R
G
S
T
S
N
F
Y
S
Q
G
L
Site 227
Y1890
R
G
S
T
S
N
F
Y
S
Q
G
L
E
S
I
Site 228
S1891
G
S
T
S
N
F
Y
S
Q
G
L
E
S
I
P
Site 229
S1919
R
R
L
Q
A
Q
L
S
H
V
S
R
E
H
S
Site 230
S1926
S
H
V
S
R
E
H
S
Q
E
T
E
S
L
R
Site 231
S1931
E
H
S
Q
E
T
E
S
L
R
E
A
L
L
S
Site 232
S1938
S
L
R
E
A
L
L
S
S
R
S
H
L
Q
E
Site 233
S1941
E
A
L
L
S
S
R
S
H
L
Q
E
L
E
K
Site 234
S1980
H
F
R
E
E
R
L
S
L
Q
E
N
D
S
R
Site 235
S1986
L
S
L
Q
E
N
D
S
R
L
Q
H
K
L
V
Site 236
S2008
E
K
Q
Q
L
F
E
S
L
Q
S
E
L
Q
I
Site 237
Y2016
L
Q
S
E
L
Q
I
Y
E
A
L
Y
G
N
S
Site 238
Y2020
L
Q
I
Y
E
A
L
Y
G
N
S
K
K
G
L
Site 239
S2023
Y
E
A
L
Y
G
N
S
K
K
G
L
K
A
Y
Site 240
Y2030
S
K
K
G
L
K
A
Y
S
L
D
A
C
H
Q
Site 241
S2031
K
K
G
L
K
A
Y
S
L
D
A
C
H
Q
I
Site 242
S2061
L
R
G
Q
L
E
Q
S
I
Q
G
N
N
C
L
Site 243
S2084
E
S
G
A
G
K
A
S
L
S
P
S
S
I
N
Site 244
S2086
G
A
G
K
A
S
L
S
P
S
S
I
N
Q
N
Site 245
S2088
G
K
A
S
L
S
P
S
S
I
N
Q
N
F
P
Site 246
S2089
K
A
S
L
S
P
S
S
I
N
Q
N
F
P
A
Site 247
S2097
I
N
Q
N
F
P
A
S
T
D
P
G
N
K
Q
Site 248
S2110
K
Q
L
L
L
Q
D
S
A
V
S
P
P
V
R
Site 249
S2113
L
L
Q
D
S
A
V
S
P
P
V
R
D
V
G
Site 250
S2130
S
P
A
L
V
F
P
S
S
A
S
S
T
P
G
Site 251
S2131
P
A
L
V
F
P
S
S
A
S
S
T
P
G
S
Site 252
S2133
L
V
F
P
S
S
A
S
S
T
P
G
S
E
T
Site 253
S2134
V
F
P
S
S
A
S
S
T
P
G
S
E
T
P
Site 254
T2135
F
P
S
S
A
S
S
T
P
G
S
E
T
P
I
Site 255
S2138
S
A
S
S
T
P
G
S
E
T
P
I
I
N
R
Site 256
T2140
S
S
T
P
G
S
E
T
P
I
I
N
R
A
N
Site 257
S2154
N
G
L
G
L
D
T
S
P
V
M
K
T
P
P
Site 258
T2159
D
T
S
P
V
M
K
T
P
P
K
L
E
G
D
Site 259
T2168
P
K
L
E
G
D
A
T
D
G
S
F
A
N
K
Site 260
S2171
E
G
D
A
T
D
G
S
F
A
N
K
H
G
R
Site 261
Y2187
V
I
G
H
I
D
D
Y
S
A
L
R
Q
Q
I
Site 262
S2188
I
G
H
I
D
D
Y
S
A
L
R
Q
Q
I
A
Site 263
S2213
S
L
V
R
S
A
C
S
F
P
G
L
E
A
Q
Site 264
T2222
P
G
L
E
A
Q
G
T
E
V
L
G
S
K
G
Site 265
S2227
Q
G
T
E
V
L
G
S
K
G
I
H
E
L
R
Site 266
S2235
K
G
I
H
E
L
R
S
S
T
S
A
L
H
H
Site 267
S2236
G
I
H
E
L
R
S
S
T
S
A
L
H
H
A
Site 268
T2237
I
H
E
L
R
S
S
T
S
A
L
H
H
A
L
Site 269
S2249
H
A
L
E
E
S
A
S
L
L
T
M
F
W
R
Site 270
S2274
L
P
G
K
V
G
E
S
T
E
R
E
L
L
E
Site 271
T2275
P
G
K
V
G
E
S
T
E
R
E
L
L
E
L
Site 272
S2287
L
E
L
R
T
K
V
S
K
Q
E
R
L
L
Q
Site 273
T2296
Q
E
R
L
L
Q
S
T
T
E
H
L
K
N
A
Site 274
S2309
N
A
N
Q
Q
K
E
S
M
E
Q
F
I
V
S
Site 275
S2316
S
M
E
Q
F
I
V
S
Q
L
T
R
T
H
D
Site 276
S2336
R
T
N
L
E
V
K
S
L
R
A
L
P
C
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation