KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
AGBL4
Full Name:
Cytosolic carboxypeptidase 6
Alias:
ATP/GTP-binding protein-like 4
Type:
Mass (Da):
62385
Number AA:
540
UniProt ID:
Q5VU57
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
A
E
G
S
Q
S
A
P
E
A
G
Site 2
S7
_
M
A
E
G
S
Q
S
A
P
E
A
G
N
D
Site 3
S62
L
G
R
V
D
Q
V
S
E
F
E
Y
D
L
F
Site 4
Y66
D
Q
V
S
E
F
E
Y
D
L
F
I
R
P
D
Site 5
T74
D
L
F
I
R
P
D
T
C
N
P
R
F
R
V
Site 6
S93
T
V
E
N
V
K
E
S
Q
R
V
I
F
N
I
Site 7
S108
V
N
F
S
K
T
K
S
L
Y
R
D
G
M
A
Site 8
S120
G
M
A
P
M
V
K
S
T
S
R
P
K
W
Q
Site 9
T121
M
A
P
M
V
K
S
T
S
R
P
K
W
Q
R
Site 10
S122
A
P
M
V
K
S
T
S
R
P
K
W
Q
R
L
Site 11
Y135
R
L
P
P
K
N
V
Y
Y
Y
R
C
P
D
H
Site 12
Y136
L
P
P
K
N
V
Y
Y
Y
R
C
P
D
H
R
Site 13
Y137
P
P
K
N
V
Y
Y
Y
R
C
P
D
H
R
K
Site 14
Y161
F
D
R
E
E
D
I
Y
Q
F
A
Y
C
Y
P
Site 15
Y165
E
D
I
Y
Q
F
A
Y
C
Y
P
Y
T
Y
T
Site 16
Y177
T
Y
T
R
F
Q
H
Y
L
D
S
L
Q
K
R
Site 17
Y188
L
Q
K
R
N
M
D
Y
F
F
R
E
Q
L
G
Site 18
T207
Q
R
K
L
D
L
L
T
I
T
S
P
D
N
L
Site 19
S210
L
D
L
L
T
I
T
S
P
D
N
L
R
E
G
Site 20
T226
E
Q
K
V
V
F
I
T
G
R
V
H
P
G
E
Site 21
T234
G
R
V
H
P
G
E
T
P
S
S
F
V
C
Q
Site 22
S236
V
H
P
G
E
T
P
S
S
F
V
C
Q
G
I
Site 23
S237
H
P
G
E
T
P
S
S
F
V
C
Q
G
I
I
Site 24
Y275
M
L
N
P
D
G
V
Y
L
G
N
Y
R
C
S
Site 25
T302
P
S
P
W
V
H
P
T
L
H
G
V
K
Q
L
Site 26
Y314
K
Q
L
I
V
Q
M
Y
N
D
P
K
T
S
L
Site 27
T319
Q
M
Y
N
D
P
K
T
S
L
E
F
Y
I
D
Site 28
Y324
P
K
T
S
L
E
F
Y
I
D
I
H
A
H
S
Site 29
Y339
T
M
M
N
G
F
M
Y
G
N
I
F
E
D
E
Site 30
S367
C
Q
N
A
E
D
F
S
Y
S
S
T
S
F
N
Site 31
Y368
Q
N
A
E
D
F
S
Y
S
S
T
S
F
N
R
Site 32
S369
N
A
E
D
F
S
Y
S
S
T
S
F
N
R
D
Site 33
T371
E
D
F
S
Y
S
S
T
S
F
N
R
D
A
V
Site 34
S372
D
F
S
Y
S
S
T
S
F
N
R
D
A
V
K
Site 35
T382
R
D
A
V
K
A
G
T
G
R
R
F
L
G
G
Site 36
Y396
G
L
L
D
H
T
S
Y
C
Y
T
L
E
V
S
Site 37
T399
D
H
T
S
Y
C
Y
T
L
E
V
S
F
Y
S
Site 38
T433
L
G
R
N
V
A
R
T
F
L
D
Y
Y
R
L
Site 39
Y438
A
R
T
F
L
D
Y
Y
R
L
N
P
V
V
E
Site 40
S468
V
Q
R
R
K
E
K
S
P
P
Y
K
H
P
L
Site 41
Y471
R
K
E
K
S
P
P
Y
K
H
P
L
L
R
G
Site 42
S481
P
L
L
R
G
P
A
S
N
Y
P
N
S
K
G
Site 43
Y483
L
R
G
P
A
S
N
Y
P
N
S
K
G
D
K
Site 44
S486
P
A
S
N
Y
P
N
S
K
G
D
K
K
S
S
Site 45
S492
N
S
K
G
D
K
K
S
S
V
N
H
K
D
P
Site 46
S493
S
K
G
D
K
K
S
S
V
N
H
K
D
P
S
Site 47
S500
S
V
N
H
K
D
P
S
T
P
F
L
K
T
R
Site 48
T501
V
N
H
K
D
P
S
T
P
F
L
K
T
R
S
Site 49
T506
P
S
T
P
F
L
K
T
R
S
P
G
R
S
Y
Site 50
S508
T
P
F
L
K
T
R
S
P
G
R
S
Y
G
D
Site 51
S512
K
T
R
S
P
G
R
S
Y
G
D
R
S
M
H
Site 52
Y513
T
R
S
P
G
R
S
Y
G
D
R
S
M
H
F
Site 53
S517
G
R
S
Y
G
D
R
S
M
H
F
L
L
G
N
Site 54
S529
L
G
N
E
I
N
H
S
S
L
A
S
K
D
L
Site 55
S530
G
N
E
I
N
H
S
S
L
A
S
K
D
L
W
Site 56
S533
I
N
H
S
S
L
A
S
K
D
L
W
I
N
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation