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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DCAF12L1
Full Name:
DDB1- and CUL4-associated factor 12-like protein 1
Alias:
WD repeat-containing protein 40B
Type:
Mass (Da):
51201
Number AA:
463
UniProt ID:
Q5VU92
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S23
V
E
A
D
A
E
S
S
P
S
Q
G
L
A
A
Site 2
S25
A
D
A
E
S
S
P
S
Q
G
L
A
A
A
D
Site 3
T47
K
R
Q
R
R
P
A
T
Y
R
S
M
A
H
Y
Site 4
Y48
R
Q
R
R
P
A
T
Y
R
S
M
A
H
Y
L
Site 5
Y54
T
Y
R
S
M
A
H
Y
L
K
V
R
E
V
G
Site 6
Y78
F
D
G
E
L
R
G
Y
A
V
Q
R
L
P
E
Site 7
T88
Q
R
L
P
E
L
L
T
E
R
Q
L
E
L
G
Site 8
T96
E
R
Q
L
E
L
G
T
V
N
K
V
F
A
S
Site 9
S103
T
V
N
K
V
F
A
S
Q
W
L
N
S
R
Q
Site 10
S139
R
I
P
L
L
R
D
S
E
A
R
L
A
Q
D
Site 11
S160
H
A
I
E
L
N
P
S
K
T
L
L
A
T
G
Site 12
T162
I
E
L
N
P
S
K
T
L
L
A
T
G
G
E
Site 13
S173
T
G
G
E
N
P
N
S
L
A
I
Y
Q
L
P
Site 14
Y177
N
P
N
S
L
A
I
Y
Q
L
P
S
L
D
P
Site 15
S210
L
S
D
T
V
A
V
S
G
S
R
D
G
T
V
Site 16
T216
V
S
G
S
R
D
G
T
V
A
L
W
R
M
D
Site 17
T230
D
P
D
K
F
D
D
T
V
A
W
H
S
E
V
Site 18
S235
D
D
T
V
A
W
H
S
E
V
G
L
P
V
Y
Site 19
Y242
S
E
V
G
L
P
V
Y
A
H
I
R
P
R
D
Site 20
S261
P
R
A
I
I
N
P
S
N
R
K
V
R
A
L
Site 21
S281
N
Q
E
L
G
A
V
S
L
D
G
Y
F
H
L
Site 22
Y314
R
D
N
V
C
L
T
Y
C
D
D
M
S
V
Y
Site 23
Y321
Y
C
D
D
M
S
V
Y
A
V
G
S
H
S
H
Site 24
S330
V
G
S
H
S
H
V
S
F
L
D
L
R
Q
D
Site 25
S346
Q
N
I
R
P
L
C
S
R
E
G
G
T
G
V
Site 26
T351
L
C
S
R
E
G
G
T
G
V
R
S
L
S
F
Site 27
S355
E
G
G
T
G
V
R
S
L
S
F
Y
R
H
I
Site 28
T364
S
F
Y
R
H
I
I
T
V
G
T
G
Q
G
S
Site 29
Y375
G
Q
G
S
L
L
F
Y
D
V
R
A
Q
K
F
Site 30
S388
K
F
L
E
E
R
A
S
A
T
L
E
S
S
S
Site 31
T390
L
E
E
R
A
S
A
T
L
E
S
S
S
G
P
Site 32
S393
R
A
S
A
T
L
E
S
S
S
G
P
A
R
R
Site 33
S395
S
A
T
L
E
S
S
S
G
P
A
R
R
K
L
Site 34
Y458
P
A
G
L
H
G
N
Y
A
G
L
W
S
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation