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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CACHD1
Full Name:
VWFA and cache domain-containing protein 1
Alias:
Type:
Mass (Da):
142290
Number AA:
1274
UniProt ID:
Q5VU97
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
R
Q
P
E
E
E
E
T
A
V
A
R
A
R
R
Site 2
T268
H
D
K
I
S
V
L
T
V
A
D
T
V
R
T
Site 3
S306
T
F
V
S
S
V
K
S
S
D
S
P
T
Q
H
Site 4
S307
F
V
S
S
V
K
S
S
D
S
P
T
Q
H
A
Site 5
S309
S
S
V
K
S
S
D
S
P
T
Q
H
A
V
G
Site 6
T311
V
K
S
S
D
S
P
T
Q
H
A
V
G
F
Q
Site 7
Y408
A
E
Q
N
S
G
K
Y
G
V
P
D
R
M
A
Site 8
S1130
R
R
S
H
Q
H
M
S
P
L
A
A
Q
E
M
Site 9
S1138
P
L
A
A
Q
E
M
S
V
R
M
S
N
L
E
Site 10
S1142
Q
E
M
S
V
R
M
S
N
L
E
N
D
R
D
Site 11
S1155
R
D
E
R
D
D
D
S
H
E
D
R
G
I
I
Site 12
S1163
H
E
D
R
G
I
I
S
N
T
R
F
I
A
A
Site 13
S1178
V
I
E
R
H
A
H
S
P
E
R
R
R
R
Y
Site 14
Y1185
S
P
E
R
R
R
R
Y
W
G
R
S
G
T
E
Site 15
S1189
R
R
R
Y
W
G
R
S
G
T
E
S
D
H
G
Site 16
T1191
R
Y
W
G
R
S
G
T
E
S
D
H
G
Y
S
Site 17
S1193
W
G
R
S
G
T
E
S
D
H
G
Y
S
T
M
Site 18
Y1197
G
T
E
S
D
H
G
Y
S
T
M
S
P
Q
E
Site 19
T1199
E
S
D
H
G
Y
S
T
M
S
P
Q
E
D
S
Site 20
S1201
D
H
G
Y
S
T
M
S
P
Q
E
D
S
E
N
Site 21
S1206
T
M
S
P
Q
E
D
S
E
N
P
P
C
N
N
Site 22
S1217
P
C
N
N
D
P
L
S
A
G
V
D
V
G
N
Site 23
T1233
D
E
D
L
D
L
D
T
P
P
Q
T
A
A
L
Site 24
T1237
D
L
D
T
P
P
Q
T
A
A
L
L
S
H
K
Site 25
Y1248
L
S
H
K
F
H
H
Y
R
S
H
H
P
T
L
Site 26
T1266
H
H
L
Q
A
A
V
T
V
H
T
V
D
A
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation