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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CTGLF1
Full Name:
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 6
Alias:
ARF GTPase-activating protein; ArfGAP with GTPase domain, ankyrin repeat and PH domain 4; Centaurin, gamma-like family, member 1; CTGLF5; CTLF3; Em:AC012044.1; MRIP2
Type:
Unknown function
Mass (Da):
73130
Number AA:
UniProt ID:
Q5VW22
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0008060
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0032312
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
L
T
C
R
V
H
P
S
V
S
L
E
F
D
Q
Site 2
S23
E
F
D
Q
Q
Q
G
S
V
C
P
S
E
S
E
Site 3
S27
Q
Q
G
S
V
C
P
S
E
S
E
T
Y
E
A
Site 4
S29
G
S
V
C
P
S
E
S
E
T
Y
E
A
G
A
Site 5
T31
V
C
P
S
E
S
E
T
Y
E
A
G
A
R
D
Site 6
Y32
C
P
S
E
S
E
T
Y
E
A
G
A
R
D
R
Site 7
S81
E
A
L
E
F
N
P
S
A
N
P
E
A
S
T
Site 8
S94
S
T
I
F
Q
R
N
S
Q
T
D
V
V
E
I
Site 9
S104
D
V
V
E
I
R
R
S
N
C
T
N
H
V
S
Site 10
T107
E
I
R
R
S
N
C
T
N
H
V
S
A
V
R
Site 11
S116
H
V
S
A
V
R
F
S
Q
Q
Y
S
L
C
S
Site 12
T124
Q
Q
Y
S
L
C
S
T
I
F
L
D
D
S
T
Site 13
T160
T
Q
R
D
A
D
R
T
L
S
I
P
D
E
Q
Site 14
S162
R
D
A
D
R
T
L
S
I
P
D
E
Q
L
H
Site 15
S170
I
P
D
E
Q
L
H
S
F
A
V
S
T
V
H
Site 16
S187
K
K
R
N
G
G
G
S
L
N
N
Y
S
S
S
Site 17
Y191
G
G
G
S
L
N
N
Y
S
S
S
I
P
S
T
Site 18
S192
G
G
S
L
N
N
Y
S
S
S
I
P
S
T
P
Site 19
S193
G
S
L
N
N
Y
S
S
S
I
P
S
T
P
S
Site 20
S194
S
L
N
N
Y
S
S
S
I
P
S
T
P
S
T
Site 21
S197
N
Y
S
S
S
I
P
S
T
P
S
T
S
Q
E
Site 22
T198
Y
S
S
S
I
P
S
T
P
S
T
S
Q
E
D
Site 23
S200
S
S
I
P
S
T
P
S
T
S
Q
E
D
P
Q
Site 24
T201
S
I
P
S
T
P
S
T
S
Q
E
D
P
Q
F
Site 25
S202
I
P
S
T
P
S
T
S
Q
E
D
P
Q
F
S
Site 26
S209
S
Q
E
D
P
Q
F
S
V
P
P
T
A
N
T
Site 27
T213
P
Q
F
S
V
P
P
T
A
N
T
P
T
P
V
Site 28
T216
S
V
P
P
T
A
N
T
P
T
P
V
C
K
R
Site 29
T218
P
P
T
A
N
T
P
T
P
V
C
K
R
S
M
Site 30
S228
C
K
R
S
M
R
W
S
N
L
F
T
S
E
K
Site 31
T232
M
R
W
S
N
L
F
T
S
E
K
G
S
D
P
Site 32
S233
R
W
S
N
L
F
T
S
E
K
G
S
D
P
D
Site 33
S237
L
F
T
S
E
K
G
S
D
P
D
K
E
R
K
Site 34
T252
A
P
E
N
H
A
D
T
I
G
S
G
R
A
I
Site 35
S255
N
H
A
D
T
I
G
S
G
R
A
I
P
I
K
Site 36
T276
R
S
G
K
W
L
K
T
W
K
K
K
Y
V
T
Site 37
Y281
L
K
T
W
K
K
K
Y
V
T
L
C
S
N
G
Site 38
T291
L
C
S
N
G
M
L
T
Y
Y
S
S
L
G
D
Site 39
Y292
C
S
N
G
M
L
T
Y
Y
S
S
L
G
D
Y
Site 40
Y293
S
N
G
M
L
T
Y
Y
S
S
L
G
D
Y
M
Site 41
S295
G
M
L
T
Y
Y
S
S
L
G
D
Y
M
K
N
Site 42
Y299
Y
Y
S
S
L
G
D
Y
M
K
N
I
H
K
K
Site 43
S323
K
V
P
G
K
W
P
S
L
A
T
S
A
C
T
Site 44
S327
K
W
P
S
L
A
T
S
A
C
T
P
I
S
S
Site 45
T330
S
L
A
T
S
A
C
T
P
I
S
S
S
K
S
Site 46
S333
T
S
A
C
T
P
I
S
S
S
K
S
N
G
L
Site 47
S334
S
A
C
T
P
I
S
S
S
K
S
N
G
L
S
Site 48
S335
A
C
T
P
I
S
S
S
K
S
N
G
L
S
K
Site 49
S337
T
P
I
S
S
S
K
S
N
G
L
S
K
D
M
Site 50
S341
S
S
K
S
N
G
L
S
K
D
M
D
T
G
L
Site 51
T346
G
L
S
K
D
M
D
T
G
L
G
D
S
I
C
Site 52
S357
D
S
I
C
F
S
P
S
I
S
S
T
T
S
P
Site 53
T361
F
S
P
S
I
S
S
T
T
S
P
K
L
N
P
Site 54
S363
P
S
I
S
S
T
T
S
P
K
L
N
P
P
P
Site 55
S371
P
K
L
N
P
P
P
S
P
H
A
N
K
K
K
Site 56
Y405
W
H
F
E
A
T
T
Y
E
E
R
D
A
W
V
Site 57
S417
A
W
V
Q
A
I
Q
S
Q
I
L
A
S
L
Q
Site 58
S422
I
Q
S
Q
I
L
A
S
L
Q
S
C
E
S
S
Site 59
S425
Q
I
L
A
S
L
Q
S
C
E
S
S
K
S
K
Site 60
S428
A
S
L
Q
S
C
E
S
S
K
S
K
S
Q
L
Site 61
S429
S
L
Q
S
C
E
S
S
K
S
K
S
Q
L
T
Site 62
S431
Q
S
C
E
S
S
K
S
K
S
Q
L
T
S
Q
Site 63
S433
C
E
S
S
K
S
K
S
Q
L
T
S
Q
S
E
Site 64
S437
K
S
K
S
Q
L
T
S
Q
S
E
A
M
A
L
Site 65
S439
K
S
Q
L
T
S
Q
S
E
A
M
A
L
Q
S
Site 66
S485
E
C
S
G
I
H
R
S
L
G
P
H
L
S
R
Site 67
S491
R
S
L
G
P
H
L
S
R
V
R
S
L
E
L
Site 68
S495
P
H
L
S
R
V
R
S
L
E
L
D
D
W
P
Site 69
S511
E
L
R
K
V
M
S
S
I
V
N
D
L
A
N
Site 70
T529
E
G
S
S
Q
G
Q
T
K
P
S
E
K
S
T
Site 71
S535
Q
T
K
P
S
E
K
S
T
R
E
E
K
E
R
Site 72
T536
T
K
P
S
E
K
S
T
R
E
E
K
E
R
W
Site 73
S546
E
K
E
R
W
I
R
S
K
Y
E
E
K
L
F
Site 74
Y548
E
R
W
I
R
S
K
Y
E
E
K
L
F
L
A
Site 75
T572
G
Q
Q
L
L
R
A
T
A
D
E
D
L
Q
T
Site 76
T595
S
C
E
E
V
N
E
T
C
G
E
G
D
G
C
Site 77
T639
A
H
G
N
T
A
L
T
Y
A
R
Q
A
S
S
Site 78
Y640
H
G
N
T
A
L
T
Y
A
R
Q
A
S
S
Q
Site 79
S645
L
T
Y
A
R
Q
A
S
S
Q
E
C
I
N
V
Site 80
S646
T
Y
A
R
Q
A
S
S
Q
E
C
I
N
V
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation